A composition for cartilage therapeutics and using method thereof

A technology for treating composition and cartilage tissue, which is applied in drug combination, bone disease, tissue regeneration, etc., and can solve the problems of time-consuming suturing of periosteum and joint defect area, leakage of chondrocyte therapeutic agent, etc.
CN1897964AInactive Publication Date: 2007-01-17CELLONTECH
0 Cites 6 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CELLONTECH
Publication Date
2007-01-17
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

A cartilage therapeutic composition is developed for clinical transplantation into articulatio genu (knee joints) or ankle joints. It has clinical significance for symptomatic cartilage defects of the femoral condyle (medial, lateral, or trochlear) and bone cartilage defects of the talus (anklebone) in human or animal hosts, The cartilage therapeutic composition comprises a mixture of components of chondrocytes isolated and expanded or differentiated from a host such as a human or animal, and thrombin and a fibrinogen matrix containing fibrinogen. An application of the cartilage therapeutic composition is that a mixture of thrombin, chondrocyte components and a fibrinogen matrix is injected into a cartilage defect region followed by solidification therein. It provides rapid healing and effective regeneration of cartilage without surgical operation. It has the merits of safety and simplicity by allowing the use of an arthroscope for transplantation.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a cartilage treatment composition and its use method. The cartilage treatment composition can be clinically implanted into the knee joint or ankle joint, especially implanted into the femoral joint (middle, lateral or trochlear portion) of a human or animal host Clinically obvious cartilage defect areas with symptoms and cartilage defect areas of the ankle (ankle bone). Background technique

[0002] Generally speaking, cartilage tissue constitutes the joints of vertebrates, and once damaged, it cannot be regenerated to its original state in vivo.

[0003] When the cartilage tissue in a joint is damaged, normal daily activities can be limited due to severe pain. Initial damage to articular cartilage tissue can progress to a chronic condition called fatal degenerative arthritis, which interferes with normal life.

[0004] Meanwhile, to treat articular cartilage damage, there is recently a treatment method that softens t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More