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Oral disintegration tablet for supplementing qi and recovering pulse and its preparing method
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A technology for oral disintegrating tablets and nourishing qi and fumai, which can be applied to pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc.
Inactive Publication Date: 2007-01-24
张晴龙
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Problems solved by technology
[0003] In the data search, no reports about Yiqi Fumai Orally Disintegrating Tablets were found
Method used
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Effect test
Embodiment 1
[0073] (1) 10kg of red ginseng, 40kg of Ophiopogon japonicus and 20kg of Schisandra chinensis are obtained according to the method in Yiqi Fumai Capsule, Volume 18 of the "New Drug Standards", and pulverized to obtain 3.0kg of the main drug;
[0080] (3) The main ingredient is mixed with pharmaceutical excipients, granulated, dried, granulated, compressed, tested and packaged to obtain the orally disintegrating tablet of the present invention.
Embodiment 2
[0082] (1) 10kg of red ginseng, 40kg of Ophiopogon japonicus and 20kg of schisandra chinensis are crushed to obtain 2.5kg of the main drug.
[0089] (3) The main ingredient is mixed with pharmaceutical excipients, granulated, dried, granulated, compressed, tested and packaged to obtain the orally disintegrating tablet of the present invention.
Embodiment 3
[0091] (1) After extracting 10kg of red ginseng, 40kg of Ophiopogon japonicus, and 20kg of Schisandra chinensis with 80% ethanol, the extract was concentrated under reduced pressure to recover ethanol, diluted with water to a solution: medicinal material ratio of 1:1, and centrifuged at a speed of 3000 rpm After 10 minutes, the treated D101 macroporous adsorption resin on the centrifuge was washed with water until it was colorless, and then eluted with 50% ethanol, the ethanol eluate was collected, the ethanol was recovered under reduced pressure, concentrated, dried, and pulverized, and the winner was obtained. Medicine 2.1kg.
[0098] (3) The main ingredient is mixed with pharmaceutical excipients, granulated, dried, granulated, compressed, tested and packaged to...
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Abstract
The present invention belongs to the field of medicine preparing technology, and is especially one kind of qi-supplementing and pulse-recovering orally disintegrating tablet and its preparation process. The qi-supplementing and pulse-recovering orally disintegrating tablet consists of main medicine component 2-3 weight portions, disintegrant 1-2 weight portions, filler 5-7 weight portions, lubricant 0.5-0.6 weight portions, and corrective 0.1-0.2 weight portions. Dissolution experiment shows that the orally disintegrating tablet has fast disintegrating and quick leaching out of the effective components. The pharmacological experiment shows that the orally disintegrating tablet has better pharmacological effect than available oral liquid.
Description
technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a Yiqi Fumai orally disintegrating tablet and a preparation method thereof. technical background [0002] The Yiqifumai preparation composed of red ginseng, Ophiopogon japonicus and Schisandra chinensis originated from the famous ancient prescription Shengmaisan in "The Origin of Medicine" in the Jin Dynasty. Clinically, it is mainly used to treat palpitations, shortness of breath, cold extremities, sweating, severe pulse and myocardial infarction, cardiogenic shock, septic shock, etc. with the above syndromes due to deficiency of both qi and yin. Volume 4 of "New Drug Standards" contains Yiqi Fumai Oral Liquid, Volume 18 contains Yiqi Fumai Capsules, and Volume 31 contains Yiqi Fumai Granules. The patent application document with the application number CN200410021920.8 discloses Yiqi Fumai preparation and its preparation method, which discloses ...
Claims
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Application Information
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