Colloid pectin bismuth dry suspensoid and its preparing process

A technology of colloidal bismuth pectin and dry suspension, which is applied in the field of bismuth agent, can solve the problems of large side effects, weak effect of Helicobacter pylori, poor curative effect, etc., and achieves the effects of strong adhesion, good colloid characteristics and alleviation of symptoms

Inactive Publication Date: 2007-02-28
黄本东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although antacids are cheap, their curative effect is poor and their side effects are large, so they are rarely used clinically at present; although H2 receptor antagonist proton pump inhibitors have a good inhibitory effect on the secretion of gastric acid a

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0027] According to the preparation method disclosed in the description, the present invention has prepared 20 formulations as shown in Table 1. The specific excipients and dosage are shown in Table 1. The results of detecting its sedimentation volume ratio according to the method of Chinese Pharmacopoeia (20000 edition) are shown in Table 1.

[0028] Some samples (prepared according to Example 20) were investigated for influencing factors, and the results are shown in Table 2.

[0029] The results show that the colloidal bismuth pectin dry suspension provided by the invention meets the regulations of the Chinese Pharmacopoeia (2000 edition) on dry suspensions.

[0030] Raw materials

[0031]

[0032]

[0033]

[0034]

[0035] The present invention is not limited to the above-mentioned best implementation mode, and any other product identical or similar to the present invention obtained by anyone under the inspiration ...

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Abstract

The invention discloses a dried suspension of colloid pectin bismuth which comprises the following constituents (by weight ratio): colloid pectin bismuth (calculated by bismuth) 50-300 parts, filling agent 600-2500 parts, flavoring agent 50-300 parts, flocculating agent 5-60 parts. The colloid has hemostatic action for hemorrhage of digestive tract.

Description

technical field [0001] The invention relates to a bismuth agent, in particular to a colloidal bismuth pectin bismuth agent. Background technique [0002] Colloidal pectin bismuth bismuth is a gastric mucosal protective agent, which forms a stable gel in the gastric acid environment, covers the mucosal surface, isolates the erosive surface and ulcer focus from gastric acid and pepsin, and protects the damaged mucosa Promote the repair and healing of ulcer tissue; stimulate the production of endogenous prostaglandins and epidermal growth factors, accelerate the healing of ulcers and the disappearance of inflammation, and have a certain hemostatic effect. [0003] Dun Wen and Zhou Erfeng studied the effect of colloidal bismuth pectin on experimental gastric and duodenal ulcers in rats. On the rat model of gastroduodenal ulcer, the effect of bismuth pectin against experimental duodenal ulcer was observed, and compared with Dele, the results: (1) The effect of bismuth pectin on ...

Claims

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Application Information

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IPC IPC(8): A61K9/10A61K31/732A61P1/04
Inventor 黄本东
Owner 黄本东
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