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Medical composite of antineoplastic

A kind of composition and medicine technology, applied in the field of medicine

Inactive Publication Date: 2007-05-02
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, at present, there are no reports on anti-tumor drugs using the interaction of sargassum, ginseng and astragalus, and compatible prescriptions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0162] Example 1 Preparation of Pseudomonas tumefaciens extract

[0163] Preparation method of Rhizoma nodules extract

[0164] Take the medicinal materials of Rhododendron sinensis, pulverize, add water to decoct twice, each time for 2 hours, add 10 times the amount of water each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.33 (70 ° C), add ethanol for precipitation twice , the alcohol content was 70% for the first time, and the alcohol content was 80% for the second time, refrigerated for 48 hours each time, filtered, the filtrate was recovered with ethanol and concentrated to 10g of crude drug per 1ml, and an appropriate amount of newly prepared egg protein was added. solution, stir, make precipitation, refrigerate for 48 hours, filter, boil the filtrate, coagulate the excess egg protein, filter, add ethanol to the filtrate to make the ethanol content to be 75%, place the precipitation, filter, and recover the ethanol from the...

Embodiment 2

[0183] Example 2 Preparation of ginseng extract with polysaccharide as main active ingredient, namely ginseng polysaccharide

[0184] Preparation process of ginseng polysaccharide:

[0185] Take the raw sun-dried ginseng, chop it, extract with 75% ethanol, reflux for 4 hours, filter, dry the medicinal residues, add water to decoct five times, combine the decoction liquid, add 0.3% activated carbon, stir for 30 minutes, let stand overnight, Filtration, passing the filtrate through a resin column, collecting the effluent, concentrating under reduced pressure, adding ethanol to make the alcohol content reach 95%, refrigerating, filtering, washing the precipitate with acetone, draining the acetone, taking out the precipitate and drying at 60-80 °C, Smash it.

[0186] Ginseng Polysaccharide Identification Experiment

[0187] (1) Take about 0.2g of this product, add 5ml of water to dissolve, add 5 drops of alkaline copper tartrate test solution, heat to produce red precipitate, co...

Embodiment 3

[0195] Example 3 Preparation of ginseng extract with total saponins as the main active ingredient, namely total ginseng saponins

[0196] Preparation technology of total ginsenosides:

[0197] Take ginseng medicinal materials, pulverize them into fine particles, extract twice with ethanol, 3 hours each time, add 10 times the amount of alcohol each time, combine the extracts, refrigerate, filter, recover ethanol from the filtrate and concentrate to thick paste, add water to an appropriate amount ( Make each 1ml equivalent to 1g of the original medicinal material), stir well, refrigerate, filter, add the filtrate to the treated macroporous resin column, first use 2V ~ 3V column volume of water for elution, discard the water wash, and then Elute with 3 times the column volume of 80% ethanol, collect the eluate, recover the ethanol, concentrate under reduced pressure to a thick paste with a relative density of 1.30-1.35, and dry in vacuo.

[0198] Identification of total ginsenos...

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PUM

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Abstract

A composite medicine for preventing and treating tumor is proportionally prepared from glabrous sarcandra herb or its extract, ginseng or its extract, and astragalus root or its extract. Its preparing process is also disclosed.

Description

1. Technical field [0001] The present invention relates to a medicinal composition for anti-tumor diseases, which is prepared from Pseudomonas vulgaris or its extract, ginseng or its extract and Astragalus or its extract, and its preparation method and use, and belongs to the technical field of medicine. 2. Background technology [0002] At present, cancer has become the number one killer of human beings, and the incidence and mortality of cancer have increased significantly in recent decades. Tumors are normal cells that are developing or mature in the human body. Under the long-term action of some adverse factors, a new organism formed by excessive proliferation or abnormal differentiation of a certain cell group will form a local mass. However, it is different from normal tissues and cells. It does not grow according to the metabolic law of normal cells, but becomes unconstrained and controlled, and does not die normally, resulting in abnormal cell morphology, function an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K36/258A61K36/185A61P35/00
Inventor 黄振华
Owner 海安江理工技术转移中心有限公司