Test paper bar for testing colloidal gold of protective antibody of rabies virus

A rabies virus and detection test strip technology is applied in the field of rabies virus protective antibody detection test strips.

Inactive Publication Date: 2007-05-16
BEIJING ZHUANGDI HAOHE BIOMEDICINE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It overcomes the disadvantages of complex, cumbersome, long-time operations, the need for instruments, professionals, laboratories with certain conditions, and the fact that it can only detect the full antibody of rabies virus but cannot detect the protective antibody of the existing technology.

Method used

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  • Test paper bar for testing colloidal gold of protective antibody of rabies virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: rabies virus protective antibody colloidal gold detection test strip (see Figure 1)

[0028] The reaction support is 6.5cm×0.4cm PCV plate; the absorbent pad is 2cm×0.4cm oil filter paper; 1.8cm×0.4cm nitrocellulose membrane is coated with anti-rabies virus polyclonal antibody; rabies virus glycoprotein; ×0.4cm colloidal gold-labeled rabies virus glass fiber membrane; the gold-labeled antigen protective film is a 2.7cm×0.4cm polyester film; that is, a rabies virus protective antibody detection test strip is formed.

Embodiment 2

[0029] Embodiment 2: rabies virus protective antibody colloidal gold detection test strip (see Figure 1)

[0030] The reaction support is 6.5cm×0.4cm PCV plate; the absorbent pad is 2cm×0.4cm oil filter paper; 1.8cm×0.4cm nitrocellulose membrane is coated with anti-rabies virus polyclonal antibody; rabies virus glycoprotein; ×0.4cm colloidal gold-labeled rabies virus glass fiber membrane; the gold-labeled antigen protective membrane is 2.7cm×0.4cm filter paper fiber; that is, a rabies virus protective antibody detection test strip is formed.

Embodiment 3

[0031] Embodiment 3: rabies virus protective antibody colloidal gold detection test strip (see Figure 1)

[0032] The reaction support is 6.5cm×0.4cm PCV plate; the absorbent pad is 2cm×0.4cm oil filter paper; 1.8cm×0.4cm nitrocellulose membrane is coated with anti-rabies virus polyclonal antibody; rabies virus glycoprotein; ×0.4cm colloidal gold-labeled rabies virus glass fiber membrane; the gold-labeled antigen protective membrane is 2.7cm×0.4cm glass fiber; that is, a rabies virus protective antibody detection test strip is formed.

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PUM

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Abstract

This invention provides one glue gold test bar to test rabies virus protective antibody, which covers rabies virus protein and rabies multiple clone antibodies on the NC film and combines glue gold rabies virus antigen and applies film analysis double antigen clamper method and tests specimen rabies virus protective antibody.

Description

technical field [0001] The invention belongs to the field of biological detection, and in particular relates to a rabies virus protective antibody detection test strip and an application thereof. Background technique [0002] Rabies is a zoonotic infectious disease caused by rabies virus. The disease is extremely dangerous. Once the onset occurs, 100% of people will die. So far, there is no effective treatment for this disease, only injection of rabies vaccine and anti-rabies serum or immunoglobulin for prevention. An important indicator of whether the injection of rabies vaccine can achieve protective effect is to detect the rabies virus antibody in the serum. Only when a sufficient amount of protective antibody is produced can the immunization be considered successful. [0003] Commonly used methods for detecting rabies virus antibodies include: rapid fluorescence focus inhibition test, radioimmunoassay, neutralization test, hemagglutination inhibition test and complement...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/569G01N33/558G01N33/544
Inventor 刘明
Owner BEIJING ZHUANGDI HAOHE BIOMEDICINE SCI & TECH
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