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Medicament for preventing and treating bacterial disease of domestic silkworm and preparation process thereof

A bacterial disease and drug technology, applied in the field of disease prevention drugs for silkworms, can solve the problems of unsatisfactory special drugs, poor water solubility of erythromycin, unstable quality, etc., achieve good control effects and application prospects, and suppress viral diseases. The effect that occurs

Inactive Publication Date: 2007-05-23
RIZHAO SANDE TECH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs have a certain curative effect on the prevention and treatment of silkworm bacteriosis, they are not ideal as special drugs for the prevention and treatment of silkworm bacteriosis.
For example, chloramphenicol is banned due to its long residual time in the organism, erythromycin is difficult to promote in production due to its poor water solubility and unstable quality, and the control effect of sand stars is relatively poor, and it is difficult to kill silkworms. purpose of bacteria

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Prepare 100ml of drug. With Florfenicol 1.5g and 95% ethanol 100ml. First put 70ml of 95% ethanol into the liquid mixing tank; then slowly add 1.5g of florfenicol powder into the liquid mixing tank, stir and dissolve, then put the remaining 30ml of 95% ethanol into the liquid mixing tank, continue Stir for 10 minutes, mix well, and filter the medicinal solution into the storage tank with a 0.8um titanium rod filter; finally fill and seal to make 50 medicines, each 2ml, each containing 30mg of florfenicol.

[0024] Instructions:

[0025] 1. Prevention of adding food: add 500ml of water to each bottle, once before the third and fourth instar silkworms, and before the dormant silkworms; once every other day after the fifth instar silkworms.

[0026] 2. Add food for treatment: Add 500ml of water to every two tubes, once every 8 hours, after three consecutive feedings, add food once a day.

[0027] The ratio of medicinal liquid to mulberry leaves is 1:10, that is, spray 5...

Embodiment 2

[0029] Prepare 100ml of drug. With Florfenicol 1g and 97% ethanol 100ml. First put 65ml of 97% ethanol into the mixing tank; then slowly add 1g of florfenicol powder into the mixing tank, stir to dissolve, then put the remaining 35ml of 97% ethanol into the mixing tank, continue stirring After 8 minutes, mix well and filter the medicinal solution into the storage tank with a 0.8um titanium rod filter; finally fill and seal to make 50 medicines, each 2ml, each containing 20mg of florfenicol.

[0030] Instructions:

[0031] 1. Prevention of adding food: add 350ml of water to each bottle, one time before silkworms at the third and fourth instars, and before silkworms dormant; once every other day after silkworms at the fifth instar.

[0032] 2. Add food for treatment: Add 350ml of water for every two tubes, once every 8 hours, after three consecutive feedings, add food once a day.

[0033] The ratio of medicinal liquid to mulberry leaves is 1:10, that is, spray 350ml of medici...

Embodiment 3

[0035] Prepare 100ml of drug. With Florfenicol 2g and 98% ethanol 100ml. First put 80ml of 98% ethanol into the mixing tank; then slowly add 2g of florfenicol powder into the mixing tank, stir to dissolve, then put the remaining 20ml of 98% ethanol into the mixing tank, continue stirring After 7 minutes, mix well and filter the medicinal solution into the storage tank with a 0.8um titanium rod filter; finally fill and seal to make 50 medicines, each 2ml, each containing 40mg of florfenicol.

[0036] Instructions:

[0037] 1. Prevention of adding food: Add 650ml of water to each bottle, one time before the third and fourth instar silkworms, and one before the dormant silkworms; once every other day from the fifth instar silkworms.

[0038] 2. Add food for treatment: Add 650ml of water for every two tubes, once every 8 hours, after three consecutive feedings, add food once a day.

[0039] The ratio of medicinal liquid to mulberry leaves is 1:10, that is, spray 650ml of medici...

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PUM

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Abstract

The invention relates to a drug used to prevent cultivated silkworm bacterial, wherein said drug is formed by fluorobenzene and 99-95% alcohol at 0.5-5:100 ration. And the production comprises that: using 60-80% of 99-95% alcohol into liquid pot; adding fluorobenzene powder into liquid pot; mixing, dissolving, and adding left alcohol into liquid pot, mixing for 5-10min; mixing and using 0.8um titanium rod filter to filter the drug into liquid storage pot; packing, and sealing. The inventive drug can completely treat silkworm bacterial, and restrain bacterial.

Description

Technical field [0001] The invention relates to the technical field of disease-preventing drugs for silkworms, in particular to a drug for feeding silkworms. [0002] The invention also relates to a preparation method of a medicine for preventing and treating bacterial diseases of silkworms. Background technique [0003] In recent years, due to changes in sericulture methods, adjustments in the structure of sericulture, changes in climate, changes in mulberry tree varieties and fertilizer management methods, and many other factors, silkworm diseases have broken out in a large area, with an average incidence of about 5%. , Accounting for more than 20% of silkworm morbidity. Among them, bacterial disease is one of the main diseases that endanger silkworm production, especially in summer and autumn with high incidence, wide range and large loss. The current main drugs for the prevention and treatment of silkworm bacteriosis are chloramphenicol, erythromycin and floxacin. Alt...

Claims

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Application Information

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IPC IPC(8): A61K31/165A61P31/04A61K31/045
Inventor 刘贤军刘发余王维民张文东赵汉相
Owner RIZHAO SANDE TECH PHARMA
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