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Osmotic delivery device having a two-way valve and dynamically self-adjusting flow channel

A fluid supply and dynamic technology, applied in the direction of flow control without auxiliary power, mechanical equipment, osmotic transportation, etc., can solve problems such as increasing equipment cost, and achieve the effect of preventing reverse diffusion and preventing fluid communication.

Inactive Publication Date: 2007-06-20
INTARCIA THERAPEUTICS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods increase the cost of the equipment due to the additional machining required on the part

Method used

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  • Osmotic delivery device having a two-way valve and dynamically self-adjusting flow channel
  • Osmotic delivery device having a two-way valve and dynamically self-adjusting flow channel
  • Osmotic delivery device having a two-way valve and dynamically self-adjusting flow channel

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Embodiment Construction

[0032] The present invention relates to a pressure-actuated two-way valve and self-regulating flow passage for controlling fluid flow in an infusion osmotically driven useful agent supply system. Components of the two-way valve and self-regulating flow passage designed to substantially prevent the passage of pore fluid therethrough when the pressure within the useful reagent container is below a predetermined down pressure, and when the pressure within the useful reagent container is above a predetermined upper pressure Prevent useful reagents from passing therebetween. This is achieved by narrowing the fluid flow passage when the pressure in the useful reagent container is below a predetermined lower pressure or above a predetermined upper pressure. At extra special high pressures, the valve can be designed to close completely at the end of the bore, or it can provide a minimum leakage path so that the maximum fluid flow is never exceeded. At zero or very low pressure, the v...

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Abstract

An implantable, osmotically-driven delivery system having a dynamic, two-way valve and self-adjusting, variable geometry fluid flow channel. As pressure within the agent delivery system goes up, the fluid channel narrows, thereby restricting flow. At exceptionally high pressures, the valve can be designed to close altogether at the orifice or delivery end, or it can provide a minimal leak path so that a maximum fluid flow is never exceeded. At zero or very low pressures, the valve will close completely at the beneficial agent reservoir end, isolating the beneficial agent formulation from external fluid infiltration and thereby eliminating diffusion of external fluid into the beneficial agent formulation.

Description

[0001] The present application is titled "Osmotic Supply Device with One-Two-Way Valve and Dynamic Self-Adjusting Flow Channel", the filing date is June 25, 2004, the application number is 02826225.5, the international filing date is November 21, 2002, Divisional application with international application number PCT / US02 / 37465. technical field [0002] The present invention relates to osmotically controlled infusion delivery devices, and more particularly to a delivery device having a two-way microvalve and dynamically self-regulating flow path to control backdiffusion and fluid delivery in an osmotically driven delivery system rate. Background technique [0003] Controlled delivery of useful agents, such as drugs, has been accomplished in a variety of ways in the medical and veterinary arts, including infusion delivery devices such as infusion osmotic delivery devices. Osmotic delivery systems deliver a useful agent very reliably over an extended period of time, called the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M31/00A61M5/145A61M39/26G05D7/01F16K17/30A61K9/00A61M37/00
CPCA61K9/0004G05D7/0133F16K17/30A61M39/26
Inventor J·G·斯科特
Owner INTARCIA THERAPEUTICS INC