Local medicine preparation containing antiinfective medicine composition and its preparing method

A composition and anti-infection technology, which can be used in drug combinations, medical preparations containing active ingredients, and medical preparations without active ingredients, etc. Not strong enough, etc., to achieve the effect of fast action, strong efficacy and convenient use

Inactive Publication Date: 2007-06-27
上海慈瑞医药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chlorogenic acid medicines mainly contain Chinese patent medicines such as honeysuckle and eucommia. Although these marketed medicines hav...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Take 1g of houttuyfonate sodium and 0.1g of chlorogenic acid, combine and pulverize, add 11ml of water for injection to dissolve, add 0.9g of sodium chloride, stir to dissolve, add water for injection to 100ml, sterilize, pack separately, and obtain eye drops liquid.

Embodiment 2

[0017] Take 1g of houttuyfonate sodium and 1.5g of chlorogenic acid, combine and pulverize, add 50ml of water for injection to dissolve, add 0.5g of sodium chloride, stir to dissolve, add water for injection to 100ml, sterilize, pack separately, and get eye drops liquid.

Embodiment 3

[0019] Take 1g of houttuyfonate sodium and 3g of chlorogenic acid, combine and pulverize, add 60ml of water for injection to dissolve, add 1.5g of sodium chloride, stir to dissolve, add water for injection to 100ml, sterilize, subpackage, and obtain eye drops .

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PUM

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Abstract

The present invention relates to local use medicine preparation containing antiinfective medicine composition, and features that the antiinfective medicine composition includes houttuynin or houttuynin sodium and chlorgenic acid in the weight ratio of 1/3 to 10 and is prepared into eye drop or eye gel. The present invention has the advantages of high antibacterial effect, high curative effect, local use, fast acting and use convenience.

Description

technical field [0001] The invention relates to a local medicinal preparation containing an anti-infection pharmaceutical composition and a preparation method thereof, which can be made into eye drops or ophthalmic gel, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Houttuyfotin, Molecular Formula C 12 h 22 o 2 , molecular weight 198.30, also known as decanoyl acetaldehyde, English name Houttuynin, has a variety of pharmacological activities, especially antibacterial and anti-inflammatory effects are the most reported. At present, the sodium sulfite adduct of houttuybene is commonly used clinically, called houttuybein sodium, molecular formula C 12 h 23 NaO 5 S, molecular weight 302.36, also known as sodium decanoyl acetaldehyde bisulfite, the English name is Sodium Houttuyfonate, Houttuyfonate sodium also has antibacterial and anti-inflammatory effects, and its physical and chemical properties are more stable. Houttuy...

Claims

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Application Information

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IPC IPC(8): A61K31/216A61K9/08A61K9/00A61K47/34A61P31/02A61P27/02A61K31/185A61K47/10
Inventor 金幸王琰付静静陈林祥朱益锋
Owner 上海慈瑞医药科技股份有限公司
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