Systems and methods for augmenting intervertebral discs

Abstract

Systems, devices and methods are provided for augmenting intervertebral discs. The systems include implantable annulus repair and augmentation devices as well as implantable prosthetic materials for replacing a portion of or augmenting the annulus and / or the nucleus pulposus. The systems further include instruments for implanting the subject devices and materials in a minimally invasive manner. The methods are directed to the minimally invasive implantation of one or more of the subject annulus repair devices and the prosthetic materials concurrently.

Description

FIELD OF THE INVENTION [0001] The present invention is directed towards the minimally invasive repair of intervertebral discs. BACKGROUND OF THE INVENTION [0002] The spinal column is formed from a number of bony vertebral bodies separated by intervertebral discs which primarily serve as a mechanical cushion between the vertebral bones, permitting controlled motions (flexion, extension, lateral bending and axial rotation) within vertebral segments. The normal, natural intervertebral disc is comprised of three components: the nucleus pulposus (“nucleus”), the annulus fibrosis (“annulus”), and two opposing vertebral end plates. [0003] The two vertebral end plates are each composed of thin cartilage overlying a thin layer of hard, cortical bone which attaches to the spongy, richly vascular, cancellous bone of the vertebral body. [0004] The nucleus is constituted of a gel-like substance having a high (about 80-85%) water content, with the remainder made up mostly of proteoglycan, type II...

AI Technical Summary

Benefits of technology

[0014] The present invention provides systems for repairing the intervertebral disc. The systems include implantable disc augmentation devices as well as implantable prosthetic materials for filling a void within the disc. The subject augmentation devices optionally provide a scaffolding which augments the disc and which also enables passage of the prosthetic material from a location outside the disc to within the void space, where the void occupies at least a portion of the annulus and/or the nucleus. The systems further include instruments for imp

Problems solved by technology

Such fissures may progress to larger tears which allow the gelatinous material of the nucleus to migrate into the outer aspects of the annulus which may cause a localized bulge or herniation.

In the event of annulus rupture, the nuclear material may escape, causing chemical irritation and inflammation of the nerve roots.

Posterior protrusions of intervertebral discs are particularly problematic since the nerve roots are posteriorly positioned relative to the intervertebral discs.

Impingement or irritation of the nerve roots not only results in pain in the region of the back adjacent the disc, but may also cause radicular pain such as sciatica.

Nerve compression and inflammation may also lead to numbness, weakness, and in late stages, paralysis and muscle atrophy, and / or bladder and bowel incontinence.

Discectomy procedures have an inherent risk since the portion of the disc to be removed is immediately adjacent the nerve root and any damage to the nerve root is clearly undesirable.

Further, the long-term success of discectomy procedures is not always certain due to the loss of nucleus polposus which can lead to a loss in disc height.

Loss of disc height increases loading on the facet joints which can result in deterioration of the joint and lead to osteoarthritis and ultimately to foraminal stenosis, pinching the nerve root.

Loss of disc height also increases the load on the annulus as well.

As the annulus fibrosis has been shown to have limited healing capacity subsequent to discectomy.

A compromised annulus may lead to accelerated disc degeneration which may require spinal interbody fusion or total disc replacement.

As with naturally-occurring defects in the annulus, the resulting surgical annulus defect may lead to post-implant complications.

Currently accepted suturing techniques are of minimal value in light of the forces normally exerted on the annulus, including an inability to adequately resist explant of the nuclear implant.

While an improvement over conventional suturing, these annulus implants and repair techniques are limited in their ability to provide the extent of circumferential and radial competency to the annulus for long-term success.

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