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Irradiation device and method for the treatment of acne and acne scars

a technology which is applied in the field of irradiation device and acne scar treatment, can solve the problems of modesty and poor results of sigurdsson, who employed only low, and achieve the effects of reducing sebum production, reducing obstructing sebaceous concrements, and prolonging effective pulse length

Inactive Publication Date: 2007-03-29
WILKENS JAN HENNRIK +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0019] Unexpectedly, this invention teaches that mean irradiation levels which are one order of magnitude lower than the threshold of 60 mW / cm2 described in WO / 022491 and below the irradiation levels employed by Sigurdsson and Meffert can be very effective if the peak pulse power exceeds the described threshold levels for a short time only. Clinical results show that the efficacy of a pulsed-light acne therapy compared to a cw-treatment with an identical spectrum can be increased by a factor of 10-20. The efficacy of acne therapy described in WO 00 / 02491 possibly relates to the killing of superficial bacteria through the blue part of the spectrum, whereas follicles can only be reached by the aforementioned green and red parts of the spectrum between 520-550 nm resp. 610-670. Pulsed irradiation is much less affected by constant threshold off-set than cw-irradiation, since the fractional contribution of the off-set is much smaller with pulsed irradiation than with cw-radiation. Therefore, the pulsed blue light which reaches the follicle can generate singlet oxygen more efficiently.
[0040] The efficacy of the radiation device can be further increased by enhancement of the oxygen concentration In addition to the measures described in WO 00 / 12491 this can be accomplished through oxygen inhalation via an oxygen mask.

Problems solved by technology

Therefore, irradiation devices with a pure blue spectral emission have to use high power and even then the results often remain modest.
This possibly explains the poor results of Sigurdsson who employed only low radiation power below or within the range of this threshold.

Method used

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  • Irradiation device and method for the treatment of acne and acne scars
  • Irradiation device and method for the treatment of acne and acne scars
  • Irradiation device and method for the treatment of acne and acne scars

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Embodiment Construction

[0058] The irradiation device 1 comprises a broadband irradiation source 2 which is preferably a xenon flashlamp. The irradiation source 2 is mounted in the focus of a parabolic reflector 3 which is open on the side averted from the focus. The exit area at the open end of the parabolic reflector 3 is preferably defined through an adjustable shutter. The adjustable shutter can adjust the area to be irradiated. The irradiation source 2 and the paraboloid reflector 3 are mounted in a housing 5. The housing 5 comprises a handpiece 6 by means of which the irradiation device 1 can be placed on the area to be treated 7. Between the radiation source 2 and the area to be treated 7 there is a luminescent foil 8 arranged which is doped with luminescent particles. The luminescent foil 8 can also be arranged in the proximity of the radiation source 2 or the shutter 4. Preferably, the luminescent foil 8 is arranged in a way that makes it easy to replace. This simplifies the necessary replacement ...

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PUM

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Abstract

An irradiation device (1) and a method for the treatment of acne and acne scars, comprising at least one source of radiation (2), the source of radiation emitting at least one broadband spectrum in the wavelength range of 320-at least 540 nm and the radiation source (2) being pulse-operable and / or movable relatively to the area to be irradiated, the pulse energy being between 0.05-10 J / cm2 and the peak irradiation intensity being between 0.5 W / cm2 and 100 kW / cm2.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application is a divisional of U.S. application Ser. No. 10 / 094,431 filed on Mar. 8, 2002, the complete disclosure of which is herein incorporated by reference, and claims priority to German application no. DE 201 09 899.7.BACKGROUND OF THE INVENTION [0002] 1. Field of the Invention [0003] The invention relates to an irradiation device and a method for the treatment of acne. [0004] 2. Brief Description of the Related Art [0005] It is known to treat acne, which is a skin disease caused by proliferation of bacteria in blocked follicles of areas of the skin that are rich in sebaceous glands together with keratosis, with blue light in the range of 400-440 nm without significant proportions of UVA, with limited success. [0006] Here we refer to the article of V. Sigurdsson et al., “Phototherapy of Acne Vulgaris with visible Light, Dermatologie 1997, 194; iss. 3, 256-260” which includes further literature references. This form of therapy ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B18/18A61N5/06
CPCA61N5/0616H01J61/125A61N2005/0644A61N2005/0642
Inventor WILKENS, JAN HENNRIKSTIRNER, ROLF
Owner WILKENS JAN HENNRIK
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