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Imaging method, device and system

a technology of imaging method and device, applied in the field of medical imaging, can solve the problems of wear debris, difficult diagnosis of osteolytic lesions, and inability to carry out less invasive procedures

Inactive Publication Date: 2007-06-07
WARSAW ORTHOPEDIC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0005] The invention provides a method and kit for substantially noninvasively diagnosing an osteolytic lesion and a method and kit for distinguishing the location or extent of an osteolytic lesion for substantially noninvasively debridement of the lesion. Ac

Problems solved by technology

Osteolysis is a common complication in total hip arthroplasty and the most common cause of component failure.
The most common source of wear debris is adhesive-abrasive wear between a femoral head and polyethylene liner.
While washing and debridement procedures are preferred approaches to lesion management, these less invasive procedures are not always available.
First, osteolytic lesions are not easily diagnosed because they can be hidden well within tissue near an implant.
Currently there are few strategies for reliably noninvasively locating and identifying lesions for debridement.

Method used

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  • Imaging method, device and system
  • Imaging method, device and system
  • Imaging method, device and system

Examples

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Embodiment Construction

[0015] The invention relates to a method that injects a contrast agent, preferably water miscible, into a contained normal anatomic cavity of the body in the vicinity of an implant. In a preferred embodiment, a contrast agent is injected into synovial fluid at a joint. Synovial fluid is a clear, thixotropic lubricating fluid secreted by membranes in joint cavities, tendon sheaths, and bursae. The injected fluid carries a contrast agent that renders a lesion radio-opaque or identifiable to available non-invasive imaging technology. The injected material can distribute evenly within the cavity space by way of diffusion. The distribution can be enhanced by external ultrasound application, or mechanical motion of the cavity space. For example, after injection into a knee, a patient can be asked to walk a number of paces to help distribute the injected material.

[0016] In the case of a knee or hip replacement, lesions can form behind or around the implanted medical device. These lesions ...

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Abstract

A method, device and system or kit treat a lesion by injecting a contrast agent into a body area to distinguish an osteolytic lesion for imaging; and delivering an effective amount of a debridement fluid to debride the distinguished lesion.

Description

BACKGROUND OF THE INVENTION [0001] The invention relates generally to medical imaging and particularly to highlighting an osteolytic lesion and debridement of an imaged highlighted lesion. In an aspect, the invention relates to a method, device and kit for distinguishing and imaging a lesion for debridement. [0002] Osteolysis is a common complication in total hip arthroplasty and the most common cause of component failure. Osteolysis is a response to wear debris. It can develop around a hip or knee implant as a result of generation of wear debris, access of the particles to the implant-bone interface and the biologic response of the implant host to the particles. Osteolysis is mediated primary by macrophages. Fibroblasts and endothelial cells also play a role. These cells are activated by the wear debris, primarily polyethylene, but also metal and polymethylmethacrylate particles. The biologic reaction to these particles is a nonspecific foreign-body reaction. Particles in the submi...

Claims

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Application Information

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IPC IPC(8): A61B6/00
CPCA61B6/4441A61B6/481A61B6/487A61B17/32037A61B19/52A61B2019/5238A61B2019/5433A61F2/34A61F2/3859A61F2/389A61F2002/30673A61F2002/30785A61F2002/30787A61F2002/30878A61F2002/3401A61F2002/488A61M5/007A61B17/1604A61B19/026A61F2/0095A61F2/30756A61F2002/2839A61F2002/30158A61F2002/30759A61B90/36A61B2090/376A61B50/30A61B2090/3933A61F2/488
Inventor SHIMKO, DANIEL A.
Owner WARSAW ORTHOPEDIC INC