Device for Withdrawing or Administering a Substance and Method of Manufacturing a Device

Abstract

A device includes a plurality of skin penetrating devices for delivering or withdrawing a substance through the skin of a patient. The device has a support formed with a top and bottom end and a plurality of channels extending axially through the support. A plurality of the skin penetrating members is positioned in the channels with a tip extending from the bottom end of the support. A coupling member is attached to the support for coupling with a fluid supply and directing the fluid to the skin penetrating members. The skin penetrating members have a length of about 100 microns to about 2000 microns and are about 30 to 50 gauge.

Description

FIELD OF THE INVENTION[0001]The present invention relates to a device for administering a substance, such as a drug or pharmaceutical agent, or withdrawing a substance transdermally to a patient. More particularly, the invention is directed to a device having an array of penetrating members and a method of manufacturing an array for delivering or removing a substance from a patient.BACKGROUND OF THE INVENTION[0002]Various substances are extracted from or delivered to the body by many known processes. One method that is often used is the subcutaneous delivery using a needle or other cannula. The use of a needle cannula is an effective method of extracting or delivering a substance but is often painful to the patient. The pain typically experienced by the patient has prompted the development of alternative methods for extracting or delivering drugs.[0003]Various devices have been proposed for introducing substances to the body by transdermal delivery methods. Transdermal delivery devi...

AI Technical Summary

Benefits of technology

The technical effect of this patent is to create a device that can sample or give substances through the skin without causing pain to the patient.

Problems solved by technology

The use of a needle cannula is an effective method of extracting or delivering a substance but is often painful to the patient.

Many transdermal delivery devices are not able to administer drugs at a sufficient rate to be used effectively.

Moreover, many drugs can not be delivered transdermally since the drugs are not able to pass through the protective skin layers.

Iontophoresis can be difficult to control the amount and rate of drug delivery.

Under some circumstances, iontophoresis can cause skin damage depending on the extent of ionization, the energy applied to ionize the drug and duration of the treatment.

A disadvantage of the devices is the cost of the manufacturing process and the time required to produce a single item.

Other processes such as wet etching, plasma etching and machining can produce fine details in the finished substrate but are not cost or time effective for commercial use.

The prior manufacturing methods and devices for the transdermal administration of drugs have exhibited limited success.

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