Intraocular shunt placement in the suprachoroidal space

Abstract

Glaucoma can be treated by implanting an intraocular shunt into the eye. Such procedures can employ various deployment devices, shunts, and implantation techniques. A method for treating glaucoma can include positioning an intraocular shunt in eye tissue such that the shunt conducts fluid from the anterior chamber to the suprachoroidal space and delivers a pharmaceutical or biological agent to the eye.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. patent application Ser. No. 14 / 313,970, filed Jun. 24, 2014; U.S. patent application Ser. No. 14 / 313,970 is a continuation-in-part of U.S. patent application Ser. No. 12 / 946,572, filed on Nov. 15, 2010, now U.S. Pat. No. 8,852,256; U.S. patent application Ser. No. 14 / 313,970 is also a continuation-in-part of U.S. patent application Ser. No. 12 / 946,222, filed on Nov. 15, 2010, now abandoned; U.S. patent application Ser. No. 14 / 313,970 is also a continuation-in-part of U.S. patent application Ser. No. 12 / 946,240, filed on Nov. 15, 2010, now U.S. Pat. No. 8,828,070; U.S. patent application Ser. No. 14 / 313,970 is also a continuation-in-part of U.S. patent application Ser. No. 12 / 946,251, filed on Nov. 15, 2010, now U.S. Pat. No. 9,095,411; U.S. patent application Ser. No. 14 / 313,970 is also a continuation-in-part of U.S. patent application Ser. No. 12 / 946,263, filed on Nov. 15, 2010, now U.S. Pat. No...

AI Technical Summary

Benefits of technology

[0064]The present inventions provide devices and methods for self-guided implantation of soft gel tissue compliant intraocular shunts in the suprachoroidal space. Shunt placement in the suprachoroidal space avoids contact with the conjunctiva, thus safeguarding the integrity of the conjunctiva. Implanting shunts made of soft, tissue compliant material avoid the creation of a cyclodialysis cleft and reduces or eliminates the risk of hypotony and related side effects.

[0065]Some embodiments of the device accomplish self-guided shunt deployment in the suprachoroidal space by having a flexible hollow shaft with a bend that biases the shunt to follow the scleral spur as it is deployed from the shaft. The hollow shaft is pre-bent to match the angle or arc of the sclera.

Problems solved by technology

Build-up of aqueous humor and resulting intraocular pressure may result in irreversible damage to the optic nerve and the retina, which may lead to irreversible retinal damage and blindness.

A common cause of open angle glaucoma is blockage in the trabecular meshwork, the fluid flow pathways that normally drain aqueous humor from the anterior chamber of the eye.

A problem with treating closed angle glaucoma with surgical intervention is that the closed anterior chamber angle prevents an operator from advancing the deployment device into the anterior chamber angle, and thus the device cannot be properly positioned to deploy an intraocular shunt.

Once inse

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