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93 results about "Cleistanone" patented technology
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Aryl naphthalene's lignans are extracted by pet. ether from Cleistanthus collinus. The bark, leaves, heartwood, fruits and other parts of this plant are rich in lignans cleistanone along with ...
Application of O-(piperidinyl) ethyl derivative of Cleistanone in preparing drugs for resisting liver fibrosis
ActiveCN104095859AStrong anti-fibroblast proliferative activityStrong proliferative activityOrganic active ingredientsDigestive systemCleistanoneLiver fibrosis
The invention relates to the field of organic synthesis and medicinal chemistry and particularly to an O-(piperidinyl) ethyl derivative of Cleistanone, a preparation method for the O-(piperidinyl) ethyl derivative of the Cleistanone and the application of the O-(piperidinyl) ethyl derivative of the Cleistanone in preparing drugs for resisting liver fibrosis. The invention synthesizes a novel O-(piperidinyl) ethyl derivative of the Cleistanone and discloses the preparation method thereof. Pharmacological experiment results show that the O-(piperidinyl) ethyl derivative of the Cleistanone has the function of resisting liver fibrosis and has the value of developing drugs for resisting liver fibrosis.
Owner:徐州乐源牧业有限公司
Application of diethylamine derivatives of cleistanone cleistanone in the preparation of anti-hepatic fibrosis drugs
ActiveCN104095857BGood anti-hepatic fibrosis effectStrong proliferative activityOrganic active ingredientsDigestive systemCleistanoneHepatic fibrosis
The invention relates to the fields of organic synthesis and medicinal chemistry, and in particular to a Cleistanone derivative, a preparation method and its application in the preparation of anti-hepatic fibrosis drugs. The present invention synthesizes a new Cleistanone derivative and discloses its preparation method. Pharmacological experiments show that the Cleistanone derivatives of the present invention have an anti-hepatic fibrosis effect, and have the value of developing anti-hepatic fibrosis drugs.
Owner:NANJING UNIV
Application of O-(piperidyl)ethyl derivative of Cleistanone in preparation of anti-low erythrocyte anemia drugs
The invention relates to the field of organic synthesis and medicinal chemistry, and in particular relates to an O-(piperidyl)ethyl derivative of Cleistanone, a preparation method thereof and application in preparation of anti-low erythrocyte anemia drugs. The invention synthesizes a new O-(piperidyl)ethyl derivative of Cleistanone and discloses its preparation method. Pharmacological experiments show that the O-(piperidyl)ethyl derivative of Cleistanone provided by the invention has an anti-low erythrocyte anemia effect, and has the value of developing anti-low erythrocyte anemia drugs.
Owner:谭家湾遗址公园运营管理(桐乡乌镇)有限公司
Application of cleistanone diethylamine derivative in preparing drug for resisting acute gout
InactiveCN104107179AReduce apoptosisHigh activityOrganic active ingredientsSkeletal disorderCleistanoneAcute gout
The invention relates to the field of organic synthesis and pharmaceutical chemistry, and specifically relates to a cleistanone derivative, a preparation method and an application of the cleistanone derivative in preparing a drug for resisting acute gout. The invention synthesizes a novel cleistanone derivative, and discloses a preparation method thereof. Pharmacology experiments show that the cleistanone derivative provided by the invention has the effects of resisting the acute gout and has the value of developing the drug for resisting the acute gout.
Owner:王英
Application of O-(tetrahydropyrrolyl)ethyl derivative of cleistanone to preparation of medicines for preventing and treating liver injuries
The invention relates to the fields of organic synthesis and medicinal chemistry and in particular relates to an O-(tetrahydropyrrolyl)ethyl derivative of cleistanone, a preparation method and an application of the O-(tetrahydropyrrolyl)ethyl derivative to preparation of medicines for preventing and treating liver injuries. The invention synthesizes the new O-(tetrahydropyrrolyl)ethyl derivative of cleistanone and discloses the preparation method of the O-(tetrahydropyrrolyl)ethyl derivative. Pharmacology experiments show that the O-(tetrahydropyrrolyl)ethyl derivative of cleistanone has the functions of preventing and treating liver injuries and has the value of developing the medicines for preventing and treating liver injuries.
Owner:NANJING UNIV
Application of Cleistanone dimethylamine derivative in preparation of antibacterial drugs
InactiveCN104083377AImprove antibacterial propertiesStrong anti-fungal activity in humansAntibacterial agentsOrganic active ingredientsCleistanoneAntibacterial drug
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and an application thereof in the preparation of antibacterial drugs. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Shown by pharmacological experiments, the Cleistanone derivative disclosed by the invention has an antibacterial effect and has a value in the development of the antibacterial drugs.
Owner:冬青(天津)生物科技有限公司
O-(piperidinyl) ethyl derivative of Cleistanone as well as preparation method and application thereof
InactiveCN104098644AGood anti-heart failure effectOrganic active ingredientsSteroidsCleistanoneChemistry
The invention relates to the field of organic synthesis and medicinal chemistry, particularly to an O-(piperidinyl) ethyl derivative of Cleistanone as well as a preparation method for the O-(piperidinyl) ethyl derivative of the Cleistanone and the application of the O-(piperidinyl) ethyl derivative of the Cleistanone in preparing drugs for resisting heart failure. The invention synthesizes a novel O-(piperidinyl) ethyl derivative of the Cleistanone and discloses the preparation method thereof. Pharmacological experiment results show that the O-(piperidinyl) ethyl derivative of the Cleistanone has the function of resisting heart failure and has the value of developing drugs for resisting heart failure.
Owner:NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
Application of O-(piperidinyl) ethyl derivative of Cleistanone in preparing drugs for resisting chronic obstructive pulmonary diseases
The invention relates to the field of organic synthesis and medicinal chemistry and particularly to an O-(piperidinyl) ethyl derivative of Cleistanone, a preparation method for the O-(piperidinyl) ethyl derivative of the Cleistanone and the application of the O-(piperidinyl) ethyl derivative of the Cleistanone in preparing drugs for resisting chronic obstructive pulmonary diseases. The invention synthesizes a novel O-(piperidinyl) ethyl derivative of the Cleistanone and discloses the preparation method thereof. Pharmacological experiment results show that the O-(piperidinyl) ethyl derivative of the Cleistanone has the function of resisting chronic obstructive pulmonary diseases and has the value of developing drugs for resisting chronic obstructive pulmonary diseases.
Owner:由日升
Application of O-(piperidyl)ethyl derivative of cleistanone to preparation of medicines for resisting acute renal failure (ARF)
The invention relates to the fields of organic synthesis and medicinal chemistry and in particular relates to an O-(piperidyl)ethyl derivative of cleistanone, a preparation method and application of the O-(piperidyl)ethyl derivative to preparation of medicines for resisting acute renal failure (ARF). The invention synthesizes a new O-(piperidyl)ethyl derivative of cleistanone and discloses the preparation method of the O-(piperidyl)ethyl derivative. Pharmacology experiments show that the O-(piperidyl)ethyl derivative of cleistanone has the function of resisting ARF and has the value of developing the medicines for resisting ARF.
Owner:SHANDONG UNIV QILU HOSPITAL
Application of O-(tetrahydropyrrole) ethyl derivative of cleistanone in preparation of medicines for preventing or treating pancreatic fibrosis
ActiveCN104147019AGood anti-fibrosis effect of pancreasOrganic active ingredientsDigestive systemCleistanoneMedicinal chemistry
The invention relates to the fields of organic synthesis and medicinal chemistry and in particular relates to an O-(tetrahydropyrrole) ethyl derivatives of cleistanone, a preparation method of the O-(tetrahydropyrrole) ethyl derivative of cleistanone as well as application of the O-(tetrahydropyrrole) ethyl derivative of cleistanone in preparation of medicines for preventing or treating pancreatic fibrosis. A novel O-(tetrahydropyrrole) ethyl derivative of the cleistanone is synthesized, and the invention also discloses a preparation method of the O-(tetrahydropyrrole) ethyl derivative. The pharmacology experiment proves that the O-(tetrahydropyrrole) ethyl derivative of the cleistanone has an effect of preventing or treating the pancreatic fibrosis and has the value of developing the medicine for preventing or treating the pancreatic fibrosis.
Owner:JASAN BIO MEDICINE JIAXING CO LTD
O-(piperazinyl) ethyl derivative of cleistanone, preparation method of O-(piperazinyl) ethyl derivative of cleistanone and use of O-(piperazinyl) ethyl derivative of cleistanone
ActiveCN104447938AImprove antibacterial propertiesStrong anti-Helicobacter pylori activityAntibacterial agentsOrganic active ingredientsCleistanoneAntibacterial drug
The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to an O-(piperazinyl) ethyl derivative of cleistanone, a preparation method of the O-(piperazinyl) ethyl derivative of cleistanone and use of the O-(piperazinyl) ethyl derivative in preparing an antibacterial drug. In the invention, the novel cleistanone derivative is synthesized and the preparation method of the novel cleistanone derivative is disclosed. A pharmacology experiment shows that the cleistanone derivative has an antibacterial effect and a value for developing the antibacterial drug.
Owner:NANJING UNIV
Application of O-(piperazinyl) ethyl derivative of cleistanone to preparation of medicine for resisting erythrocyte hypoplastic anemia
The invention relates to the fields of organic synthesis and pharmaceutical chemistry, in particular to O-(piperazinyl) ethyl derivative of cleistanone, and a preparation method and the application of the O-(piperazinyl) ethyl derivative to the preparation of medicine for resisting erythrocyte hypoplastic anemia. The invention compounds new O-(piperazinyl) ethyl derivative, and discloses a preparation method thereof. Pharmacology experiments show that the O-(piperazinyl) ethyl derivative has the effect of resisting erythrocyte hypoplastic anemia, and has the value of developing medicine for resisting erythrocyte hypoplastic anemia.
Owner:冬青南京生物科技有限公司
Application of 0-(1H-tetrazole)ethyl derivative of Cleistanone to preparation of anti-heart-failure medicine
InactiveCN104814968AGood anti-heart failure effectOrganic active ingredientsSteroidsCleistanone1H-tetrazole
The invention relates to the field of organic synthesis and medicinal chemistry, in particular to a Cleistanone derivative, a preparation method and application of the Cleistanone derivative to preparation of an anti-heart-failure medicine. A novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Pharmacology experiments show that the Cleistanone derivative has an anti-heart-failure function and has the value of developing an anti-heart-failure medicine.
Owner:NANJING GUANGKANGXIE BIOLOGICAL MEDICAL TECH
Application of Cleistanone diethylamine derivative in preparation of drugs for resisting anemia caused by low red blood cell level
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and use thereof in the preparation of drugs for resisting anemia caused by low red blood cell level. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Pharmacological experiments indicate that the Cleistanone derivative disclosed by the invention has an effect of resisting anemia caused by low red blood cell level and has a value in the development of the drugs for resisting anemia caused by low red blood cell level.
Owner:湖北团黄贡茶有限公司
Application of cleistanone O-(1H-tetrazole)ethyl derivative in preparation of antibacterial drugs
InactiveCN104840470AImprove antibacterial propertiesStrong anti-fungal activity in humansAntibacterial agentsOrganic active ingredientsCleistanone1H-tetrazole
The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to a cleistanone derivative, and a preparation method and an application thereof in preparation of antibacterial drugs. The new cleistanone derivative is synthesized, and the preparation method is disclosed. Pharmacological experiments indicate that the cleistanone derivative has an antibacterial effect and has a value of development of the antibacterial drugs.
Owner:NANJING GUANGKANGXIE BIOLOGICAL MEDICAL TECH
Cleistanone O-(morpholinyl)ethyl derivative and preparation method and application thereof
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of anti-rhinitis drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has an anti-rhinitis effect and has a value in the development of the anti-rhinitis drugs.
Owner:NANJING UNIV
Application of O-(piperazinyl) ethyl derivative of cleistanone to preparation of medicine for resisting acute gout
InactiveCN104288160AReduce apoptosisHigh activityOrganic active ingredientsSkeletal disorderCleistanoneAcute gout
The invention relates to the fields of organic synthesis and pharmaceutical chemistry, in particular to O-(piperazinyl) ethyl derivative of cleistanone, and a preparation method and the application of the O-(piperazinyl) ethyl derivative to the preparation of medicine for resisting acute gout. The invention compounds new O-(piperazinyl) ethyl derivative, and discloses a preparation method thereof. Pharmacology experiments show that the O-(piperazinyl) ethyl derivative has the effect of resisting acute gout, and has the value of developing medicine for resisting acute gout.
Owner:广州往圣生物科技有限公司
Application of Cleistanone dimethylamine derivative in preparation of anti-rhinitis drugs
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and use thereof in the preparation of anti-rhinitis drugs. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Shown by pharmacological experiments, the Cleistanone derivative disclosed by the invention has an anti-rhinitis effect and has a value in the development of the anti-rhinitis drugs.
Owner:南通香境生物医药科技有限公司
Application of O-(tetrahydropyrrole) ethyl derivative of cleistanthus sumatranus ketone in preparation of medicine for treating or preventing renal fibrosis
InactiveCN104188978AGood anti-renal fibrosis effectOrganic active ingredientsUrinary disorderCleistanoneKetone
The invention relates to the fields of organic synthesis and medicinal chemistry, and particularly relates to an O-(tetrahydropyrrole) ethyl derivative of cleistanthus sumatranus ketone Cleistanone, a preparation method and an application of the O-(tetrahydropyrrole) ethyl derivative in preparation of a medicine for preventing or treating renal fibrosis. The invention synthesizes a novel O-(tetrahydropyrrole) ethyl derivative of the cleistanthus sumatranus ketone Cleistanone, and discloses a preparation method of the O-(tetrahydropyrrole) ethyl derivative. A pharmacology experiment shows that the O-(tetrahydropyrrole) ethyl derivative of the cleistanthus sumatranus ketone Cleistanone has the effect of preventing or treating the renal fibrosis, and has the value of developing the medicine for preventing or treating the renal fibrosis.
Owner:于钦密
Application of Cleistanone O-(morpholinyl)ethyl derivative in preparation of heart failure resisting drugs
ActiveCN104188983AGood anti-heart failure effectOrganic active ingredientsCardiovascular disorderCleistanoneHeart failure
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of heart failure resisting drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has a heart failure resisting effect and has a value in the development of the heart failure resisting drugs.
Owner:北京宽厚医药科技有限公司
Cleistanone O-(imidazolyl) ethyl derivative, and preparation method and application thereof
The invention relates to the fields of organic synthesis and pharmaceutical chemistry, in particular to a Cleistanone O-(imidazolyl) ethyl derivative, and a preparation method and application thereof in the preparation of anti-rhinitis drugs. The invention synthesizes a new Cleistanone O-(imidazolyl) ethyl derivative and discloses a preparation method thereof. Pharmacological experiments prove that the Cleistanone O-(imidazolyl) ethyl derivative has the effect of resisting to rhinitis and has the value of anti-rhinitis drug development.
Owner:NANJING UNIV
Application of Cleistanone O-(morpholinyl)ethyl derivative in preparation of anti-hypoxia drugs
ActiveCN104188982AGood anti-hypoxia effectOrganic active ingredientsAntinoxious agentsCleistanoneStereochemistry
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of anti-hypoxia drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has an anti-hypoxia effect and has a value in the development of the anti-hypoxia drugs.
Owner:徐州三禾饲料有限公司
Application of Cleistanone O-(piperazinyl)ethyl derivative in preparation of hepatic fibrosis resisting drugs
ActiveCN104434928AGood anti-hepatic fibrosis effectStrong proliferative activityOrganic active ingredientsDigestive systemCleistanoneMedicine
The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(piperazinyl)ethyl derivative, a preparation method thereof and use thereof in the preparation of hepatic fibrosis resisting drugs. According to the invention, a novel Cleistanone O-(piperazinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(piperazinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(piperazinyl)ethyl derivative disclosed by the invention has a hepatic fibrosis resisting effect and has a value in the development of the hepatic fibrosis resisting drugs.
Owner:嘉善县魏塘资产管理有限公司
Application of O-(pyrrolidin)ethyl derivatives of Cleistanone to preparation of anti-osteoporosis drug
The invention relates to the fields of organic synthesis and pharmaceutical chemistry and particularly relates to O-(pyrrolidin)ethyl derivatives of Cleistanone, a preparation method of the O-(pyrrolidin)ethyl derivatives of Cleistanone and an application of the O-(pyrrolidin)ethyl derivatives of Cleistanone to preparation of an anti-osteoporosis drug. The invention discloses novel O-(pyrrolidin)ethyl derivatives of Cleistanone and a preparation method of the novel O-(pyrrolidin)ethyl derivatives of Cleistanone. Pharmacological experiments prove that the O-(pyrrolidin)ethyl derivatives of Cleistanone have an anti-osteoporosis effect and has a value of developing the anti-osteoporosis drug.
Owner:路春芝
Application of cleistanone O-(benzimidazolyl) ethyl derivative in preparation of drugs for treating acute gout
InactiveCN104825470AReduce apoptosisHigh activityOrganic active ingredientsAntipyreticCleistanoneMedicine
The invention relates to the fields of organic synthesis and pharmaceutical chemistry, and specifically relates to a cleistanone derivative, a preparation method thereof, and an application of the cleistanone derivative in the preparation of drugs for treating acute gout. A novel cleistanone derivative is synthesized, and a preparation method thereof is disclosed. The pharmacological experiments show that the cleistanone derivative has an effect on resisting acute gout and can be used to develop drugs for treating acute gout.
Owner:NANJING GUANGKANGXIE BIOLOGICAL MEDICAL TECH
Application of cleistanone O-(benzimidazolyl) ethyl derivative in preparation of anti-inflammatory drugs
InactiveCN104825467AEffective anti-inflammatory effectEnhanced inhibitory effectOrganic active ingredientsAntipyreticCleistanoneStereochemistry
The invention relates to the fields of organic synthesis and pharmaceutical chemistry, and specifically relates to a cleistanone O-(benzimidazolyl) ethyl derivative, a preparation method thereof, and an application of the cleistanone O-(benzimidazolyl) ethyl derivative in the preparation of anti-inflammatory drugs. A novel cleistanone O-(benzimidazolyl) ethyl derivative is synthesized, and a preparation method thereof is disclosed. The pharmacological experiments show that the cleistanone O-(benzimidazolyl) ethyl derivative has an anti-inflammatory effect and can be used to develop anti-inflammatory drugs.
Owner:NANJING GUANGKANGXIE BIOLOGICAL MEDICAL TECH
Applications of cleistanone O-(benzimidazolyl) ethyl derivative in preparation of drugs for preventing or treating pancreatic fibrosis
InactiveCN104825466AGood anti-fibrosis effect of pancreasOrganic active ingredientsDigestive systemMedicineCleistanone
The invention relates to the fields of organic synthesis and pharmaceutical chemistry, and specifically relates to a cleistanone O-(benzimidazolyl) ethyl derivative, a preparation method thereof, and applications of the cleistanone O-(benzimidazolyl) ethyl derivative in the preparation of drugs for preventing or treating pancreatic fibrosis. A novel cleistanone O-(benzimidazolyl) ethyl derivative is synthesized, and a preparation method thereof is disclosed. Pharmacology experiment results show that the provided cleistanone O-(benzimidazolyl) ethyl derivative has an effect on preventing or treating pancreatic fibrosis, and thus the cleistanone O-(benzimidazolyl) ethyl derivative is advantageously used to produce drugs for preventing or treating pancreatic fibrosis.
Owner:NANJING GUANGKANGXIE BIOLOGICAL MEDICAL TECH
Application of diethylamine derivative of Cleistanone in preparation of medicine resistant to acute renal failure
The invention relates to the fields of organic synthesis and medicinal chemistry and particularly to a derivative of Cleistanone, the preparation method for the derivative of the Cleistanone and the usage of the derivative of Cleistanone in preparing medicine resistant to acute renal failure. According to the invention, a novel derivative of the Cleistanone is synthesized and the preparation method for the novel derivative of the Cleistanone is disclosed. Pharmacological experiments indicate that the derivative of the Cleistanone provided by the invention has the function of resisting the acute renal failure and has the value of developing medicine resistant to the acute renal failure.
Owner:SHANDONG UNIV QILU HOSPITAL
Application of O-(1H-tetrazolyl) ethyl derivative of cleistanone in preparation of medicines for treating or preventing renal fibrosis
The invention relates to the fields of organic synthesis and pharmaceutical chemistry and specifically relates to an O-(1H-tetrazolyl) ethyl derivative of cleistanone, a preparation method and application thereof in preparation of medicines for treating or preventing renal fibrosis. The invention synthesizes a new O-(1H-tetrazolyl) ethyl derivative of cleistanone and discloses the preparation method thereof. Pharmacological experiments show that the O-(1H-tetrazolyl) ethyl derivative of cleistanone has an effect for preventing or treating the renal fibrosis and has the value of developing the medicines for preventing or treating the renal fibrosis.
Owner:NANJING UNIV
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