Application of Cleistanone diethylamine derivative in preparation of drugs for resisting anemia caused by low red blood cell level

A technology of low red blood cells and cleistanone, applied in the field of preparation of cleistanone derivatives, can solve the problems of insufficient hematopoietic raw materials or utilization barriers
CN104147014AActive Publication Date: 2014-11-19湖北团黄贡茶有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
湖北团黄贡茶有限公司
Publication Date
2014-11-19

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Abstract

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and use thereof in the preparation of drugs for resisting anemia caused by low red blood cell level. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Pharmacological experiments indicate that the Cleistanone derivative disclosed by the invention has an effect of resisting anemia caused by low red blood cell level and has a value in the development of the drugs for resisting anemia caused by low red blood cell level.
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Description

technical field

[0001] The present invention relates to the fields of organic synthesis and medicinal chemistry, in particular to a Cleistanone derivative, a preparation method and an application thereof. Background technique

[0002] There are different classifications of anemia based on different clinical features. Such as: acute and chronic anemia according to the progress of anemia; proliferative anemia (such as hemolytic anemia, iron deficiency anemia, megaloblastic anemia, etc.) and hypoplastic anemia (such as aplastic anemia) ).

[0003] Clinically, it is often classified from the pathogenesis and etiology of anemia:

[0004] 1. Anemia with reduced erythropoiesis

[0005] The abnormality of hematopoietic cells, bone marrow hematopoietic microenvironment and hematopoietic raw materials affect erythropoiesis, which can form erythropoietic anemia.

[0006] (1) Anemia caused by abnormal hematopoietic stem and progenitor cells

[0007] 1) Aplastic anemia (AA) AA is a ...

Claims

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