59results about How to "Effective anti-inflammatory effect" patented technology

The invention belongs to the technical field of atherosclerotic targeted drugs, and discloses a medicine for resisting atherosclerotic inflammation and an anti-inflammatory effect detection method, and the medicine for resisting atherosclerotic inflammation is artesunate. The method for detecting the anti-inflammatory effect of the medicine for resisting atherosclerotic inflammation comprises thefollowing steps: performing an in-vitro experiment of using ox-LDL to induce VSMC phenotype to be converted into inflammatory phenotype cells; performing an in vivo experiment of using ox-LDL to induce VSMC phenotype to be converted into inflammatory phenotype cells. According to the invention, a molecular biology method is adopted, and the artesunate and target protein NLRP3 binding target is comprehensively investigated through a cell model and an animal model for inhibiting ox-LDL from inducing phenotypic transformation of VSMCs inflammatory cells by artesunate; and the anti-inflammatory effect and the molecular mechanism of artesunate in AS vascular inflammatory injury are illustrated by inhibiting the anti-inflammatory effect and the molecular mechanism of ox-LDL induced VSMCs inflammatory cell phenotypic transformation.

The present invention relates to an application of indole-2, 3-dione for preparing for an anti-inflammation drug. The indole-2, 3-dione is natural product or synthetic product with low toxicity, little side effect and good anti-inflammation and diminishing inflammation effects.

The present invention is related to the inventive compositions comprising the extract of mixed herbs with Lonicera japonica THUNB and Anemarrhena asphodeloides BUNGE showing potent anti-inflammatory activity, therefore, it can be used as the effective and safe therapeutics or health food for treating and preventing arthritic disease.

The invention relates to the field of organic synthesis and medicinal chemistry and in particular relates to a composition, a preparation method and an application of the composition to preparation of anti-inflammatory medicines. The invention discloses the composition and the preparation method thereof. Pharmacological experiments show that the composition has the anti-inflammatory effect and has the value in developing the anti-inflammatory medicines.

The invention relates to an intravenous injection lipid emulsion having anti-inflammatory and anti-thrombosis functions as well as a preparation method and an application thereof. The lipid emulsion consists of anti-inflammatory lipid, lipid having an anti-platelet aggregation function, an emulsifier, polyhydric alcohol and other pharmaceutical accessories, wherein the anti-inflammatory lipid is lipid which can form timnodonic acid or butyric acid through metabolism in vivo; and the lipid having an anti-platelet aggregation function is lipid which can form docosapentaenoic acid through metabolism in vivo. On one hand, the lipid emulsion disclosed by the invention can effectively relieve inflammatory reaction in patients, and can significantly reduce platelet aggregation and reduce the risk of high-risk thrombosis on the other hand. In addition, by virtue of reasonable lipid composition, the lipid emulsion can improve metabolism rate of fatty acid lipid and accelerate energy supply.

The invention relates to the fields of organic synthesis and medicinal chemistry, in particular to a composition, a preparation method and application of the composition in preparation of anti-inflammatory drugs. The invention discloses the composition and the preparation method thereof. A pharmacological experiment shows that the composition has the anti-inflammatory effect, and has the value for developing anti-inflammatory drugs.

The invention belongs to the technical field of organic synthesis and medicinal chemistry, and in particular relates to a biotin-labeled naringin, a preparation method and an application thereof. The biotin-labeled naringin probe prepared by the present invention has the structural formula shown in formula (1), and the compound has a stable structure, simple synthesis and anti-inflammatory activity. Pharmacological experiments show that the biotin-labeled naringin probe of the present invention has better anti-inflammatory effect than independent naringin, and has the value of developing anti-inflammatory drugs; on the other hand, the biotin-labeled naringin It can be used as a molecular probe to explore the drug target of naringin, which is of great significance for exploring the mechanism of action of naringin in the inflammatory process.

The invention discloses a plant residue composition with anti-inflammatory effect and application thereof. The plant residue composition disclosed by the invention is composed of the following components by mass percent: 0.6-3.4% of safflower extraction residue, 0.5-4.1% of hawthorn extraction residue and 0.3-2.7% of panax notoginseng extraction residue. The plant residue composition has the effects of balancing oil secretion, inhibiting bacteria, diminishing inflammation and relieving itching when being applied to body wash.

The invention discloses an application of keratinocyte growth factor-2 in the preparation of medicine for treating chronic cervicitis. The keratinocyte growth factor-2 is used as an active ingredient to prepare vaginal suppositories, vaginal effervescent tablets, vaginal gels and other vaginal administration dosage forms. The obtained medicine has good anti-inflammation effect on chronic cervicitis, promotes the repair of cervical epithelium, and has the advantages of simple operation, good effect and no toxic or side effect.