38results about How to "Strong anti-Helicobacter pylori activity" patented technology

The invention relates to the field of organic synthesis and medicinal chemistry, in particular to a derivative of Cleistanine, a preparation method and application of Cleistanine in preparing anti-bacterial medicines. According to the invention, a novel Cleistanine derivative is synthesized, and the invention discloses the preparation method thereof; the pharmacological experiments show that the derivative of Cleistanine has antibacterial effect and value for developing anti-bacterial medicines.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone derivative, a preparation method thereof and an application thereof in the preparation of antibacterial drugs. According to the invention, a novel Cleistanone derivative is synthesized, and a preparation method of the novel Cleistanone derivative is disclosed. Shown by pharmacological experiments, the Cleistanone derivative disclosed by the invention has an antibacterial effect and has a value in the development of the antibacterial drugs.

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to an O-(piperazinyl) ethyl derivative of cleistanone, a preparation method of the O-(piperazinyl) ethyl derivative of cleistanone and use of the O-(piperazinyl) ethyl derivative in preparing an antibacterial drug. In the invention, the novel cleistanone derivative is synthesized and the preparation method of the novel cleistanone derivative is disclosed. A pharmacology experiment shows that the cleistanone derivative has an antibacterial effect and a value for developing the antibacterial drug.

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to a cleistanone derivative, and a preparation method and an application thereof in preparation of antibacterial drugs. The new cleistanone derivative is synthesized, and the preparation method is disclosed. Pharmacological experiments indicate that the cleistanone derivative has an antibacterial effect and has a value of development of the antibacterial drugs.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of antibacterial drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has an antibacterial effect and has a value in the development of the antibacterial drugs.

The invention provides application of polaprezinc in preparing medicine for eradicating helicobacter pylori. Clinical tests prove that polaprezinc has high helicobacter pylori resisting activity and can effectively inhibit the activity of helicobacter pylori, the bactericidal efficacy of polaprezinc and medicine concentration are in positive correlation, and polaprezinc can be used for preparing related medicines for treating gastritis, gastric ulcer, gastric cancer, dodecadactylitis, duodenal ulcer, duodenal cancer and other diseases closely related to helicobacter pylori.

The invention relates to the field of organic synthesis and medicinal chemistry, in particular to a Daphmalenine A derivative, a preparation method and application of the Daphmalenine A derivative in preparation of antibacterial drug. A new Daphmalenine A derivative is synthesized. Pharmacological experiments show that the Daphmalenine A derivative has antibacterial effect and has value in developing the antibacterial drug.

The invention relates to the fields of organic synthesis and pharmaceutical chemistry, in particular to a composition, a preparing method and application thereof to preparation of antibacterial drugs. The invention discloses the composition and the preparing method thereof. Pharmacology experiments show that the composition has an antibacterial effect and has the value of developing the antibacterial drugs.

The invention relates to the field of organic synthesis and medicinal chemistry and in particular relates to a composition, a preparation method and an application of the composition to preparation of antibacterial medicines. The invention discloses the composition and the preparation method thereof. Pharmacological experiments show that the composition has the antibacterial effect and has the value in developing the antibacterial medicines.

The invention provides a traditional Chinese medicine composition. An in-vitro activity experiment shows that the traditional Chinese medicine composition has very strong helicobacter pylori (HP) resisting activity; and the traditional Chinese medicine composition is prepared from 18 parts of twoflower micromeria, 20 parts of all grass of unispike kyllinga, 15 parts of chalky guinine fungus, 12 parts of roots or barks of shortpedicel heteropanax, 18 parts of roots of caudate two-seeded palm and 20 parts of barks of Indian quassiawood. The traditional Chinese medicine composition can be used for treating diseases including acute and chronic gastritis, gastric ulcer and duodenal ulcer and the like, can be applied to medicines for treating the acute and chronic gastritis, the gastric ulcer and the duodenal ulcer, and has remarkable advancement.

The invention provides a composition and application thereof to antibacterial medicine and relates to the field of organic synthesis and medical chemistry, in particular to a composition, a preparation method and application of the composition to antibacterial medicine preparation. The invention discloses the composition and the preparation method thereof. Pharmacological experiments show that the composition has the antibacterial function and has value in antibacterial medicine development.

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to an O-(piperazinyl) ethyl derivative of cleistanone, a preparation method of the O-(piperazinyl) ethyl derivative of cleistanone and use of the O-(piperazinyl) ethyl derivative in preparing an antibacterial drug. In the invention, the novel cleistanone derivative is synthesized and the preparation method of the novel cleistanone derivative is disclosed. A pharmacology experiment shows that the cleistanone derivative has an antibacterial effect and a value for developing the antibacterial drug.

The invention relates to the fields of organic synthesis and medicinal chemistry, in particular to a composition, a preparation method and application of the composition in preparation of antibacterial drugs. The invention discloses the composition and the preparation method thereof. A pharmacological experiment shows that the composition has the antibacterial effect, and has the value for developing antibacterial drugs.

The invention relates to the field of organic synthesis and pharmaceutical chemistry, in particular to a composition, a preparing method and application of the composition in antibacterial drugs. The invention discloses a composition and a preparing method thereof. It is indicated through pharmacological experiments that the composition has antibacterial effect and value of developing antibacterial drugs.

The present invention relates to the fields of organic synthesis and medicine chemistry, and in particular relates to a composition 77083001030592, a preparation method and application thereof in preparing antibacterial drugs. The present invention discloses a composition 77083001030592 and a preparation method thereof. Pharmacological experiments show that the composition 77083001030592 has antibacterial effect, and the value in development of antibiotics.

The invention relates to the field of organic synthesis and pharmaceutical chemistry and particularly relates to a Cleistanone O-(morpholinyl)ethyl derivative, a preparation method thereof and application thereof in the preparation of antibacterial drugs. According to the invention, a novel Cleistanone O-(morpholinyl)ethyl derivative is synthesized, and a preparation method of the novel Cleistanone O-(morpholinyl)ethyl derivative is disclosed. Shown by pharmacological experiments, the Cleistanone O-(morpholinyl)ethyl derivative disclosed by the invention has an antibacterial effect and has a value in the development of the antibacterial drugs.

The invention relates to the field of organic synthesis and pharmaceutical chemistry, in particular to compositions, preparing methods and applications of the compositions in preparing antibacterial agents. The invention discloses a composition and a preparing method thereof. Pharmacology experiments indicate that the composition has an antibacterial effect and has a value in the development of antibacterial agents.

The invention relates to the field of organic synthesis and medicinal chemistry and in particular relates to a composition, a preparation method and an application of the composition to preparation of antibacterial medicines. The invention discloses the composition and the preparation method thereof. Pharmacological experiments show that the composition has the antibacterial effect and has the value in developing the antibacterial medicines.

The invention relates to the field of organic synthesis and medicinal chemistry, in particular to a composition, a preparation method of the composition and application of the composition in the preparation of antibacterial drugs. The invention also discloses a composition and a preparation method thereof. Pharmacological experiments show that the composition of the invention is antibacterial and is worthy of being developed into antibacterial drugs.

The invention relates to the field of organic synthesis and medicine chemistry, in particular to a composition, a preparation method and application of the composition to preparing antibacterial medicine. The invention discloses the composition and the preparation method thereof. Pharmacological experiments show that the composition has the antibacterial function and has value in antibacterial medicine development.

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to an O-(imidazolyl) ethyl derivative of cleistanone, as well as a preparation method and application thereof in preparation of an antibacterial drug. The invention synthesizes a novel O-(imidazolyl) ethyl derivative of the cleistanone and discloses the preparation method thereof. Pharmacological experiments show that the O-(imidazolyl) ethyl derivative of the cleistanone has an antibacterial effect and has a value for developing antibacterial drugs.

The invention discloses application of a composition of O-(dichloroethylamino)ethyl and O-(di(2-methylthioethyl)amino)ethyl derivatives of Artalbic acid in antibacterial drugs, relates to the field of organic synthesis and medicinal chemistry and particularly relates to a composition of O-(dichloroethylamino)ethyl and O-(di(2-methylthioethyl)amino)ethyl derivatives of Artalbic acid, a preparation method and application thereof in preparation of antibacterial drugs. The invention discloses a composition of O-(dichloroethylamino)ethyl and O-(di(2-methylthioethyl)amino)ethyl derivatives of Artalbic acid and a preparation method thereof. Pharmacological experiments indicate that the composition of O-(dichloroethylamino)ethyl and O-(di(2-methylthioethyl)amino)ethyl derivatives of Artalbic acid has an antibacterial effect and a value of developing antibacterial drugs.

The invention relates to the field of organic synthesis and medicinal chemistry, in particular to a composition, a preparation method and an application of the composition in preparing antibacterial drugs, and discloses a composition and a preparation method thereof. Pharmacological experiments indicate that the composition has the antibacterial function, and has the value of developing the antibacterial drugs.

The invention relates to the fields of organic synthesis and medicinal chemistry, in particular to a composition, a preparation method and application of the composition in preparing antibacterial agents. The invention discloses a composition and a preparation method thereof. Pharmacological experiments prove that the composition has antibacterial effect and has the value in developing the antibacterial agents.

The invention relates to the field of organic synthesis and medicinal chemistry and in particular relates to a composition, a preparation method and an application of the composition to preparation of antibacterial medicines. The invention discloses the composition and the preparation method thereof. Pharmacological experiments show that the composition has the antibacterial effect and has the value in developing the antibacterial medicines.

The invention relates to the field of organic synthesis and medicine chemistry, in particular to a composition, a preparation method and application of the composition to preparation of antibacterial medicine. The invention discloses the composition and the preparation method of the composition. Pharmacological experiments show that the composition has the antibacterial effect, and has antibacterial medicine development values.

The invention relates to the field of organic synthesis and pharmaceutical chemistry, in particular to compositions, preparing methods and applications of the compositions in preparing antibacterial agents. The invention discloses a composition and a preparing method thereof. Pharmacology experiments indicate that the composition has an antibacterial effect and has a value in the development of antibacterial agents.

The invention discloses a method for preparing egg yolk lecithin by adopting a two-step subcritical extraction technology, and belongs to the technical field of subcritical fluid extraction. According to the method, frozen egg yolk gel is used as a raw material, egg yolk powder is obtained through dilution, homogenization, centrifugation and spray drying, then the two-step subcritical extraction technology is adopted for preparing the egg yolk lecithin, solvent residues are avoided, the yield of lecithin in the obtained product is as high as 92.7%, the purity is as high as 95.8%, and the egg yolk lecithin can be directly used for medicines, food and health care products. According to the method, the extraction temperature and pressure are mild, protection of high-value components such as DHA, carotenoid and folic acid in a by-product egg oil is facilitated, and the application potential in medicine and food industries is huge; and meanwhile, another obtained by-product natural antibody egg yolk immune globulin has high helicobacter pylori resisting activity, and can effectively treat diseases such as gastric ulcer. Therefore, egg yolk resources can be fully utilized, and the comprehensive utilization value of the egg yolk is improved.

The invention discloses an application of a composition of Salviskinone A benzimidazolyl and di(2-methylmercapto ethyl)amido derivatives in antibacterial drugs, relates to the fields of organic synthesis and medicinal chemistry, and particularly relates to the composition of the Salviskinone A benzimidazolyl and di(2-methylmercapto ethyl)amido derivatives, and a preparation method and the application thereof in preparation of the antibacterial drugs. Provided are the composition of the Salviskinone A benzimidazolyl and di(2-methylmercapto ethyl)amido derivatives and the preparation method thereof. Pharmacological experiments indicate that the composition has an antibacterial effect and has the value for development of the antibacterial drugs.