36results about How to "Good anti-hepatic fibrosis effect" patented technology

The invention involves the use of the total flavonoids of the fields to prepare for the treatment of drugs for the treatment of liver fibrosis.Total yellow total flavonoids are an active ingredient extracted from Hypericum Japonicum Thunb.).The present invention further provides a pharmaceutical composition for the treatment of liver fibrosis. The drug composition includes an effective treatment dose as an active ingredients as a field -based yellow flavonoids, and a pharmaceutical acceptable carrier.The present invention shows that through animal experiments, the total flavonoids of the fields have a good anti -liver fibrosis, and have no poisonous side effects. They can be used to prepare drugs for the treatment of liver fibrosis and are used for clinical liver fibrosis.

The invention relates to a method for separating and extracting C15H18O5 from Cichorium glandulosum Boiss.et Hout and use of C15H18O5 the English name of which is 11B, 13-Dihydrolacurin. The method is characterized by comprising the following steps: soaking the root of Cichorium glandulosum Boiss.et Hout by ethanol; collecting the percolate by a percolation method; obtaining a thick extract by a reduced pressure distillation device; passing the extract through a silicagel column, an octadecylsilyl column and a Sephadex LH-20 column; eluting; and drying the eluant by the reduced pressure distillation device to obtain dry powder which is the monomer C15H18O5, the English name of which is 11B, 13-Dihydrolacurin. The compound has the effect of preventing anti-hepatic fibrosis, namely, the compound inhibits activating and proliferating effect of hepatic stellate cells, so that the C15H18O5 with the English name of 11B, 13-Dihydrolacurin can be used as a lead compound for preventing anti-hepatic fibrosis.