The invention discloses a multi-functional computer fault diagnosis instrument. The multi-functional computer fault diagnosis instrument comprises a central processing unit, an LED display unit, a VGA interface unit, a RJ 45 interface unit, an audio power amplifier module, a BNC interface unit, a USB&PS/2 interface unit, an LED flashlight unit, a voltage comparator unit, a PCI gold finger interface, a keyboard, a lithium battery power supply unit, an electric leakage detection gold finger, a DC input interface, a power module, a wireless & infrared receiver, an audio input interface, an audio output interface, a loudspeaker, AUDIO row needle interfaces and 2P row needle interfaces. The multi-functional computer fault diagnosis instrument can not only detect a computer host fault, but also can detect whether a computer display, a sound, an earphone, the keyboard and a reticle are good or not, detect whether a computer microphone, a computer sound card, a monitoring camera and the wireless & infrared remote controller output signals or not and detect whether a computer case shell has electrical leakage or not, and the computer maintenance work becomes more relaxing and rapid.