The invention discloses a growth factor-containing cosmetic and a preparation method thereof. The preparation method comprises the following steps: (1) adding water and disodium ethylenediamine tetraacetate into a water phase pot, stirring and mixing evenly, then adding glycerin, 1,3‑Propylene glycol, cetearyl alcohol, plant extracts, and hydroxyethyl cellulose are stirred and mixed evenly; (2) Add glycerol monostearate, sorbitan monopalmitate, and shea butter to the oil phase Stir in the pot and mix evenly; (3) Homogenous. The cosmetics containing growth factors and the preparation method thereof of the present invention are safe and non-irritating, have both nutrition and moisturizing effects, have special functions such as nutrition, anti-aging, stable emulsification, antibacterial and anti-inflammatory, promote wound healing and repair damaged cells, and have high efficiency Moisturizing, long-lasting water-locking effect, can continuously maintain the moisture content of the stratum corneum of the skin, ensure the moisture of the skin, make the skin firm, rich in elasticity and luster, regular use will make the skin more delicate, smooth and full of elasticity.