Nicergoline oral cavity disintegration tablet and its preparation method

Abstract

An oral disintegrating tablet of nicergoline contains nicergoline and auxiliaries including sorbitol, methylacryl copolymer resin (Eudragit L30D), citric acid, sodium dicarbonate, magnesium stearate, SiO2 and lemon perfume.

Description

technical field

[0001] The invention relates to a dosage form of medicine, in particular to a nicergoline oral disintegrating agent and a preparation method thereof. technical background

[0002] Oral disintegrating agents are very necessary for those who have difficulty swallowing, especially the elderly, children and the environment where water is inconvenient. Play a role. Orally rapidly disintegrating tablets are high-porosity oral preparations prepared by the British Weyth Company (Weyth) using freeze-drying technology in the late 1970s, and developed rapidly in the 1990s. Nicergoline has α-receptor blocking effect and vasodilator effect, which can strengthen the energy metabolism of brain cells, increase the utilization of oxygen and glucose; promote the conversion of neurotransmitter dopamine to increase nerve conduction, and strengthen the synthesis of brain proteins , good brain function. It is mainly used to improve cerebral arterioscler...