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Therapeutic infusion containing fructose

A therapeutic and fructose technology, applied in the field of therapeutic infusion, can solve problems such as undiscovered technical literature and the like

Active Publication Date: 2009-12-30
ANHUI FENGYUAN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Extensive searches have been carried out for the above problems, but no relevant technical literature has been found

Method used

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  • Therapeutic infusion containing fructose
  • Therapeutic infusion containing fructose
  • Therapeutic infusion containing fructose

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: prepare levofloxacin lactate fructose injection (specification: 100ml: 0.1g levofloxacin lactate and 5g fructose)

[0030] Formula and ratio:

[0031] Levofloxacin Lactate 125.6g

[0032] Fructose 5000g

[0033] Appropriate amount of water for injection

[0034]

[0035] Full volume 100L

[0036] Preparation:

[0037] 1. Weigh and dissolve levofloxacin lactate and fructose in 20L of water for injection preheated to 70°C to 90°C according to the prescription, and dissolve completely.

[0038] 2. Add about 6g of activated carbon (the amount added is 0.03% of the concentrated solution). Insulate and stir at 70°C to 90°C for 15 minutes.

[0039] 3. Remove the carbon by suction filtration, and rinse the activated carbon by suction filtration with some water for injection.

[0040] 4. Add water for injection to the full amount.

[0041] 5. Intermediate inspection.

[0042] 6. Fine filtration until the clarity is qualified

...

Embodiment 2

[0046] Embodiment 2: prepare tinidazole fructose injection (specification: 100ml: 0.4g tinidazole and 5g fructose)

[0047] Formula and ratio:

[0048] Tinidazole 400g

[0049] Fructose 5000g

[0050] Dilute hydrochloric acid / sodium hydroxide appropriate amount

[0051] Appropriate amount of water for injection

[0052]

[0053] Full volume 100L

[0054] Preparation:

[0055] 1. Dissolve tinidazole and fructose in 20L of water for injection preheated to 70°C to 90°C according to the prescription amount, and dissolve completely.

[0056] 2. Add about 6g of activated carbon (the amount added is 0.03% of the concentrated solution). Insulate and stir at 70°C to 90°C for 15 minutes.

[0057] 3. Remove the carbon by suction filtration, and rinse the activated carbon by suction filtration with some water for injection.

[0058] 4. Use 0.1mol / L hydrochloric acid solution or 0.1mol / L sodium hydroxide solution to adjust the pH of the feed solution to ...

Embodiment 3

[0065] Embodiment 3: prepare piracetam fructose injection (specification: 100ml: 8g tinidazole and 5g fructose)

[0066] Formula and ratio:

[0067] Piracetam 8000g

[0068] Fructose 5000g

[0069] Appropriate amount of water for injection

[0070]

[0071] Full volume 100L

[0072] Preparation:

[0073] 1. Dissolve piracetam and fructose in 20L of water for injection preheated to 70°C to 90°C according to the prescription amount, and dissolve completely.

[0074] 2. Add about 6g of activated carbon (the amount added is 0.03% of the concentrated solution). Insulate and stir at 70°C to 90°C for 15 minutes.

[0075] 3. Remove the carbon by suction filtration, and rinse the activated carbon by suction filtration with some water for injection.

[0076] 4. Add water for injection to the full amount.

[0077] 5. Intermediate inspection.

[0078] 6. Fine filtration until the clarity is qualified

[0079] 7. Filling, film release, stoppering and cap...

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Abstract

The invention relates to a therapeutic infusion containing diphosphatase, wherein the transfusion comprises the following components (by weight portions): medicament for treatment 0.01-20, fructose 5-10. The medicament includes medicines for the treatment of infection, cardiovascular diseases, diabetes, digestive diseases and hepatic diseases.

Description

Technical field: [0001] The invention relates to a therapeutic transfusion in the technical field of medicine, in particular to a class of therapeutic transfusion containing fructose. Background technique: [0002] Therapeutic infusion has become a pharmaceutical preparation widely used clinically because of its advantages of good absorption, quick onset, and convenient administration, and has made great contributions to relieving the pain of the majority of patients. The current clinical therapeutic infusions are mainly large-capacity injections made of sodium chloride and glucose additives, such as fluconazole glucose injections used clinically, which are mainly used for postoperative anti-deep infection; puerarin sodium chloride injections Diammonium Glycyrrhizinate Glucose Injection is mainly used for hepatoprotective treatment of patients with liver disease. However, there are often some special cases in clinical practice, such as some patients have poor tolerance to g...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/26A61K31/5383A61K31/496A61P31/04
Inventor 汪洪湖丁汉锦李士桥
Owner ANHUI FENGYUAN PHARM CO LTD