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Compounding traditional Chinese medicine, and its use

A compound and traditional Chinese medicine technology, applied in the fields of food, medicine and beverages, can solve the problems of insufficient curative effect, no reports on the treatment of DN by traditional Chinese medicine, and insufficient targeting of kidney diseases.

Inactive Publication Date: 2007-07-25
QINGFENGGE MEDICINE TECH SHANGHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the two can delay the progress of renal failure, they still have adverse effects such as hyperkalemia and cough, and are not suitable for patients with renal artery stenosis and severe renal impairment (An Maozhu, Sun Jing et al., Angiotensin Converting Enzyme Adverse reactions and prevention of inhibitors, Chinese Journal of New Drugs, 1999, (6): 403)
Usually, Chinese patent medicines for the treatment of DN include Shenyan Kangfu Tablets, Shenfukang Capsules, Liuwei Dihuang Pills, etc. However, these medicines for treating nephropathy are not well targeted and curative enough for the treatment of nephropathy caused by diabetes concurrently, and it is difficult to achieve satisfactory clinical results. Effect
[0075] According to literature search and novelty search, so far, no relevant reports on the treatment of DN with this traditional Chinese medicine compound have been found.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0350] Embodiment 1, the preparation of this Chinese medicine compound drop capsule

[0351] Take 40g of the Chinese medicine compound obtained above, add Zhudan Gao 15, chlorpheniramine maleate 0.3g, houttuyonin sodium 6g, add 40%-60% starch, dextrin, carboxymethyl starch, phosphoric acid Calcium hydrogen and other fillers, 0.5-10% disintegrant sodium carboxymethyl cellulose, hydroxypropyl cellulose are made into granules and dried, and glidant magnesium stearate and micro silica gel are added to make them dry. Then pack into capsules to obtain the product, namely the Chinese medicine compound capsules.

Embodiment 2

[0352] Embodiment 2, the preparation of this Chinese medicine compound capsule

[0353] (1) Prescription

[0354] The traditional Chinese medicine compound 1000.0g

[0355] Microcrystalline Cellulose 1000g

[0356] Sodium carboxymethyl starch 140g

[0357] Anhydrous ethanol amount

[0358] Talc powder 80g

[0359]

[0360] Made a total of 10000 capsules

[0361] (2) Preparation process According to the above prescription, the raw material drug, the Chinese medicine compound and other auxiliary materials in the prescription were respectively passed through a 100-mesh sieve, dried at 60°C, and the prescription amount was weighed. The Chinese medicine compound and microcrystalline cellulose, sodium carboxymethyl starch Mix evenly with equal amount incremental method, make soft material with appropriate amount of ethanol, granulate with 30 mesh sieve, dry at 50-60°C for 2 hours, granulate with 30 mesh sieve, add p...

Embodiment 3

[0362] Embodiment 3, the preparation method 1 of this Chinese medicine compound powder injection

[0363] Take 30g of the traditional Chinese medicine compound, add 30g of dextran, add 500ml of water for injection, stir to dissolve; add water for injection to 2000ml, add 3.0g of activated carbon for needles, stir for 30 minutes; decarbonize and filter; use 0.22μm microporous Membrane filtration; filling into sterile vials, 2ml per bottle, half stoppered; freeze-dried, then stoppered and capped.

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PUM

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Abstract

A Chinese medicine for treating diabetes and nephrosis is prepared from 4 Chinese-medicinal materials including astragalus root, rhubarb, etc.

Description

technical field [0001] The invention relates to the technical fields of medicine, food and beverage, in particular to a Chinese medicine compound and its use, more specifically to a Chinese medicine compound and its use. Background technique [0002] (1) Resource overview [0003] Astragalus (Huangqi, RADIX ASTRAGALI, Mikvetch Root) is the dried root of Astragalus membranaceus (Fisch.) Bge.Var. (Bge.) Hsiao or Astragalus membrane pod Astragalus membranaceus (Fisch.) Bge. It invigorates qi and solidifies the exterior, diuretic to support poison, evacuates pus, suppresses sores and promotes granulation. For qi deficiency and fatigue, lack of appetite, loose stools, subsidence of middle qi, prolonged diarrhea and prolapse of the anus, bloody stool and metrorrhagia, surface deficiency and spontaneous sweating, qi deficiency and edema, carbuncle and gangrene that are difficult to burst, long-term ulceration, blood deficiency and jaundice, internal heat and quenching thirst; chro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/14A61P3/10A61P13/12
Inventor 吕仁和赵进喜郑清明王征
Owner QINGFENGGE MEDICINE TECH SHANGHAI
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