Qingkailing Preparation for great transfusion and its preparation process
A large infusion and preparation technology, applied in anti-inflammatory agents, pharmaceutical formulations, drug delivery, etc., can solve the problems of increased workload of medical staff, difficulty in product quality control, adverse reactions, etc., to prevent cross-contamination, ensure medication safety, The effect of improving the quality of medication
Inactive Publication Date: 2010-12-01
TSINGHUA UNIV
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Problems solved by technology
However, Qingkailing injection also has the following deficiencies in clinical application: 1. The pharmaceutical composition of Qingkailing injection contains chlorogenic acid, which is unstable under visible light, and the photosensitive surface of the small injection is highly dispersed due to the high degree of dispersion of the medicine in the small injection. increase, thus making Qingkailing injection perishable and poor in stability
2. The clarity of small injections of traditional Chinese medicine is prone to problems, and the product quality is difficult to control
3. Since Qingkailing preparations often need to be used in large doses in clinical practice, taking Qingkailing small injections to extract glucose or sodium chloride to obtain Qingkailing large infusions, the intermediate links are likely to cause cross-infection, and the safety of medication is difficult protection, but also increase the workload of medical staff
In addition, due to the complex chemical composition and preparation process of Qingkailing injection, there are often reports of adverse reactions in clinical application.
Method used
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Abstract
The Qingkailing preparation for great transfusion is prepared with cholic acid 1.2-2.0 weight portions, hyodeoxycholic acid 1.4-2.4 weight portions, buffalo horn 9-16 weight portions, baicalin 1.8-3.2 weight portions, nacre 18-32 weight portions, prepared cape jasmine extract liquid 9-16 weight portions, prepared isatis root extract liquid 75-125 weight portions, and prepared honeysuckle extract liquid 23-38 weight portions. The present invention also discloses the preparation process of the Qingkailing preparation for great transfusion. The Qingkailing preparation for great transfusion has high clarity, high stability, high safety and other advantages.
Description
A kind of Qingkailingda infusion preparation and preparation method thereof technical field The invention relates to a traditional Chinese medicine preparation, in particular to a Qingkailingda transfusion preparation and a preparation method thereof. Background technique The series of Qingkailing preparations developed from the ancient prescription Angong Niuhuang Pills by dismantling the formula and reducing the flavor, currently have Qingkailing injection, Qingkailing powder injection, Qingkailing oral liquid, Qingkailing granules, etc. Dosage forms, Qingkailing injection in small injections is the most commonly used clinically. Qingkailing Injection has the effects of clearing away heat and detoxification, calming the nerves, and treating acute and chronic hepatitis, severe cold, high fever and other diseases. In 1995, it was listed as an essential drug by the Ministry of Health of the People's Republic of China, and was designated as one of the twenty first-aid clini...
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/744A61K9/08A61P1/16A61P29/00A61K35/32A61K31/7048A61K31/575A61K35/56A61K35/618
Inventor 罗国安王义明刘清飞梁琼麟汪红英
Owner TSINGHUA UNIV
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