Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Novel medical function of cnidium monnieri lactone

A new cnidactone and drug technology, applied in the field of medicine, can solve the problem that the anticardiocerebral ischemic activity of new cnidactone has not been reported.

Inactive Publication Date: 2007-09-19
海南盛科天然药物研究院有限公司
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In recent years, domestic and foreign studies have focused on several representative 3-hydrocarbylphthalides, such as ligustilide, but less research has been done on the pharmacological activity of neocnidolide. Cardiocerebral ischemia activity has not been reported

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0014] Take the dried rhizome of Ligusticum yunnannesis (Sinodiesise yunnannesis Wolff), a Umbelliferae plant, crush it into coarse powder, and perform supercritical extraction with CO2 at an extraction pressure of 25MPa, an extraction temperature of 40°C, and an extraction time of 6 hours. 2 The flow rate is 2L / Kg angelica·h, the extract is filtered, the filtrate is left to stand, and the oil layer is taken to obtain Ligusticum yunnanensis essential oil. The essential oil yield averaged about 1.5%.

[0015] Silica gel column chromatography separates cnidactone, the ratio of essential oil to column chromatography silica gel is 1:10, and petroleum ether (30-60° C.) ether gradient eluent is used to collect cnidactone components, and the solvent is recovered. Instantly.

[0016] Preparation Example 1

[0017] Take the dried rhizome of Ligusticum yunnannesis (Sinodiesise yunnannesis Wolff), a Umbelliferae plant, crush it into coarse powder, extract the volatile oil by steam dist...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Application of novel cnidiumlactone for preparing a drug for treating ischemic heart disease and ischemic cerebrovascular disease.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the medical application of neocnidilide. Background technique [0002] Neocnidilide, also known as neocnidilide, has a chemical name of n-butyltetrahydrophthalide. Neocni lactone is a 3-hydrocarbyl phthalide compound extracted from Ligusticum edulis, Ligusticum chuanxiong and other plants. [0003] In recent years, domestic and foreign studies have focused on several representative 3-hydrocarbylphthalides, such as ligustilide, but less research has been done on the pharmacological activity of neocnidolide. The activity in cardiocerebral ischemia has not been reported yet. [0004] Cardiovascular and cerebrovascular diseases are common and frequently-occurring diseases that endanger human life and health. They are characterized by high morbidity, disability, mortality and recurrence. The number of patients with cardiovascular and cerebrovascular diseases in my country is incre...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/365A61P9/10
Inventor 吴巍邵萌滕厚雷刘军锋翟大伟
Owner 海南盛科天然药物研究院有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com