Allograft nerve graft, the method for preparing the same and uses thereof

A technology of grafts and nerves, applied in the medical field, can solve problems such as surgical failure, little clinical application value, and different structural nerve basement membranes
CN101095963AInactive Publication Date: 2008-01-02GENERAL HOSPITAL OF PLA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GENERAL HOSPITAL OF PLA
Publication Date
2008-01-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a new kind of nerve allotransplant, the preparation method and its medical application. The invention employs chemical extraction method to remove the schwann cell, axon and myelin sheath that can cause rejection for nerve allotransplant, stores stroma cell and three-dimensional pipeline structure for axon regeneration, and provides intact regenerative frame. The physical and biochemical property of nerve allotransplant are similar to that of normal nerve, and can be used as nerve allotransplant for damaged nerve.
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Description

technical field

[0001] The present invention relates to a nerve graft material, its preparation method and its application, in particular to a kind of allogeneic nerve graft in which the Schwann cells, axons and myelin sheaths that cause rejection are completely removed, but at the same time the basement membrane tube remains intact and the clinical application of the allogeneic nerve graft belong to the field of medicine. Background technique

[0002] The repair of peripheral nerve defects is a clinical problem, and its treatment should focus on solving two problems, one is the bridging repair of nerve defects, and the other is the selective docking of nerve fibers with distant target organs. At present, autologous nerve transplantation is still the standard operation for solving nerve defects in the clinical treatment process. However, due to the limited source of autologous nerves and many complications at the donor site, the medical community has been looking for biomate...

Claims

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