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Ophthalmic operating special-purpose colored perfusate

A technology of ophthalmic surgery and perfusion solution, which is applied in the direction of surgical drugs, active ingredients of alkaline/alkaline earth metal chlorides, drug combinations, etc., can solve the problem of no perfusion solution, and achieve the effect of shortening time, reducing surgical injury, and easy operation

Active Publication Date: 2008-02-20
SCHOOL OF OPHTHALMOLOGY & OPTOMETRY WENZHOU MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In summary, the current literature search shows that in order to achieve the purpose of increasing the visibility of intraocular tissues, the existing domestic and foreign literatures are all about the research on dyes in intraocular surgery, but there is no research on perfusion fluid.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025]Example 1: The special colored perfusion solution for ophthalmic surgery includes sodium chloride: 6.6mg / ml, which is 1650mg / 250ml, potassium chloride: 0.36mg / ml, which is 90mg / 250ml, calcium chloride: 0.18mg / ml, which is 45mg / 250ml , magnesium sulfate: 0.3mg / ml or 75mg / 250ml, sodium bicarbonate: 2.1mg / ml or 525mg / 250ml, sodium fluorescein: 1mg / 250ml. Specifications: 250ml, 500ml.

Embodiment 2

[0026] Embodiment 2: The special colored perfusion solution for ophthalmic surgery includes sodium chloride: 6.6mg / ml, which is 1650mg / 250ml, potassium chloride: 0.36mg / ml, which is 90mg / 250ml, calcium chloride: 0.18mg / ml, which is 45mg / 250ml , magnesium sulfate: 0.3mg / ml or 75mg / 250ml, sodium bicarbonate: 2.1mg / ml or 525mg / 250ml, sodium fluorescein: 10mg / 250ml. Specifications: 250ml, 500ml Example 3: The special colored perfusion solution for ophthalmic surgery includes sodium chloride: 6.6mg / ml or 1650mg / 250ml, potassium chloride: 0.36mg / ml or 90mg / 250ml, calcium chloride: 0.18mg / ml ml is 45mg / 250ml, magnesium sulfate: 0.3mg / ml is 75mg / 250ml, sodium bicarbonate: 2.1mg / ml is 525mg / 250ml, sodium fluorescein: 2.5mg / 250ml. Specifications: 250ml, 500ml.

Embodiment 4

[0027] Embodiment 4: The special colored perfusion solution for ophthalmic surgery includes sodium chloride: 6.6mg / ml, which is 1650mg / 250ml, potassium chloride: 0.36mg / ml, which is 90mg / 250ml, calcium chloride: 0.18mg / ml, which is 45mg / 250ml , magnesium sulfate: 0.3mg / ml or 75mg / 250ml, sodium bicarbonate: 2.1mg / ml or 525mg / 250ml, sodium fluorescein: 0.25mg / 250ml. Specifications: 250ml, 500ml.

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PUM

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Abstract

The present invention relates to a colored perfusion liquid exclusively for ophthalmic surgery. The colored perfusion liquid exclusively for ophthalmic surgery of the present invention includes conventional ophthalmic balanced salt solution and is characterized in that the present invention further contains 0.001 to 0.1mg / ml fluorescein sodium. The present invention firstly proposes the intraocular colored perfusion liquid and a concept of colored surgery, the present invention has the advantages that: the present invention can be filled in the anterior chamber, vitreous body, lens capsular bag and other lacunas, and can form the contrast with the intraocular transparent and semi-permeable membrane tissues, such as, cornea, lens capsule membrane, lens, vitreous body, retina and so on, therefore, the operator can identify such structures easily and the tissues which are difficult to identify become visible, therefore, the surgery becomes easy, the operation is accurate, the time is shorten, the retina, lens capsule membrane and other main structures are protected, the surgical complications are reduced, and better surgical effects are achieved accordingly. In addition, the present invention changes and overcomes the problems that the past localized staining method is time-consuming and needs to rinse, the surgical process is complicated, the operation is fairly troublesome, and the method can not carry out the differential display of the around tissues, that is the scope is too small etc.

Description

technical field [0001] The invention relates to a special colored perfusate for ophthalmic surgery. Background technique [0002] With the development of modern microsurgical instruments, microscopic instruments are widely used in ophthalmic surgery, and the intraocular surgery technology has become more and more perfect and mature. Cataract extraction has been widely carried out in hospitals at all levels, and vitreoretinal surgery has also begun to be gradually carried out in large and medium-sized hospitals, and the number has increased year by year, saving many blind or near-blind eyes. In ophthalmic surgery, the perfusate is in direct contact with the corneal endothelium, lens capsule, retina and other tissues in the eye, so there are strict requirements for the perfusate used in surgery, including the composition and pH of the perfusate, so as to minimize its impact on ocular tissues. injuries, especially those with long operating times. Ophthalmic balanced salt solu...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61P41/00
Inventor 宋宗明赵振全瞿佳王勤美
Owner SCHOOL OF OPHTHALMOLOGY & OPTOMETRY WENZHOU MEDICAL COLLEGE
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