Highly effective extraction method for magnolol and honokiol crude extract

Abstract

The invention discloses a method for extracting magnolol and honokiol crude extract with high efficiency, the method is that: the magnolol is dried up and crushed and sieved into 30 mesh, the magnolol is added to edible alcohol twice at the weight proportion of one grams of magnolol powder to 12 to 20ml edible alcohol, the extract temperature is 80 to 90 DEGC, the extract time is 2.0 to 3.0 hours each time, the concentration of edible alcohol is 50 to 70 percent, the two extraction crude filter liquors are combined and sieved into 200-mesh nylon fabric, a high speed centrifuge is used for centrifuging and clarifying and a clear liquid is taken out; the clear liquid at the temperature of 40 to 45 DEG C is carried out vacuum concentration by a rotary evaporator, the edible alcohol solvent is recovered and is frozen and dried in vacuum so as to obtain the crude extract, the extract rate of magnolol and honokiol is obviously higher than that of the prior art, the amounted manufacturing cost is relatively low. The method is harmless to the human body as well as to the environment by adopting edible alcohol for extraction; therefore, the method is particularly safe.

Description

Technical field:

[0001] The invention relates to a technology for extracting effective components of medicinal plants, in particular to a high-efficiency extraction method for magnolol and honokiol crude extract. Background technique:

[0002] Magnolia officinalis Rehd.et Wils. and M.biloba (Rehd.et Wils.) Cheng, Magnolia officinalis Rehd.et Wils., a deciduous tree of Magnoliaceae, are used as medicine with dry bark, branch bark and root bark. The active ingredients in magnolia bark mainly include magnolol (magnolol), honokiol (honokiol), isomagnolol, trihydroxy magnolol, destrihydroxy magnolol, wherein magnolol, honokiol Mainly, accounting for about 3% to 5% of the original medicinal materials.

[0003] In order to give full play to the pharmacological efficacy of magnolia bark, there are currently many studies on the extraction of magnolol and honokiol, mainly including alkali extraction and acid precipitation method, water extraction method, ethanol extraction method, al...