Application of chlorogenic acid in preparing medicine with treating woman organ tumor function

A technology of chlorogenic acid and medicine, which is applied in the application field of chlorogenic acid in the preparation of medicines with the effect of treating female organ tumors, which can solve the problems of patients' intolerance, impact on quality of life, and high toxicity

Inactive Publication Date: 2008-03-26
SICHUAN JIUZHANG BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The commonly used chemotherapeutic drugs are highly toxic, and patients are usually unable to tolerate them, which often seriously affects the quality of life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 0.9% sodium chloride intravenous injection of embodiment 1 chlorogenic acid

[0016] Prescription one:

[0017] Chlorogenic acid with a purity greater than 95% 1g

[0018] Citric acid 1.0g

[0019] Sodium citrate 0.5g

[0020] Sodium chloride 18g

[0021] Water for injection 2000ml

[0022]

[0023] A total of 1,000 injections of 2 ml were made according to the routine operation of injections, each containing 1 mg of chlorogenic acid.

[0024] Prescription two:

[0025] Chlorogenic acid with a purity greater than 95% 3000g

[0026] Sodium chloride 4500g

[0027] Water for injection 500,000ml

[0028]

[0029] 1000 bottles of injections of 500 ml were made according to the routine operation of injections, and each bottle contained 3 grams of chlorogenic acid.

[0030] Prescription three:

[0031] Chlorogenic acid with a purity greater than 95% 3000g

[0032] Cyclophosphamide ...

Embodiment 2

[0040] Embodiment 2 contains the sterile powder injection of sodium chloride

[0041] Prescription one:

[0042] Chlorogenic acid sterile powder with a purity greater than 95% 1g

[0043] Sodium chloride sterile powder 18g

[0044] Mannitol 48g

[0045]

[0046] A total of 1000 2ml powder injections were made according to the routine operation of sterile powder injection, each containing 1 mg of chlorogenic acid.

[0047] Prescription two:

[0048] Chlorogenic acid sterile powder with a purity greater than 95% 3000g

[0049] Sodium chloride sterile powder 45g

[0050] Mannitol 120g

[0051]

[0052] A total of 1000 5ml powder injections were made according to the routine operation of sterile powder injection, each containing 3 grams of chlorogenic acid.

[0053] Prescription 3 and Prescription 4: The components of each prescription in Example 1 were freeze-dried by freeze-drying equi...

Embodiment 3

[0054] Example 3 Chlorogenic Acid 5% Glucose Injection for Intravenous Injection

[0055] Prescription one:

[0056] Chlorogenic acid (purity greater than 95%) 2g

[0057] Citric acid 1.0g

[0058] Sodium citrate 0.5g

[0059] Glucose 100g

[0060] Water for injection 2000ml

[0061]

[0062] A total of 1000 2ml injections were made according to the routine operation of injections, each containing 2 mg of chlorogenic acid.

[0063] Prescription two:

[0064] Chlorogenic acid (purity greater than 95%) 1500g

[0065] Glucose 1000g

[0066] Water for injection 20,000ml

[0067]

[0068] A total of 1000 injections of 20 ml were made according to the routine operation of injections, each containing 1.5 grams of chlorogenic acid.

[0069] Prescription three:

[0070] Chlorogenic acid (purity greater than 95%) 3000g

[0071] Glucose 100g

[0072] Water for injection 1000,000ml

[0073] ...

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PUM

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Abstract

The present invention relates to an application of chlorogenic acid in preparation of medicine for curing female cancers, such as mammary cancer, oophoroma and carcinoma of uterus. Said medicine is made up by using chlorogenic acid as basic effective component and pharmaceutically-acceptable auxiliary component through a certain preparation process.

Description

technical field [0001] The invention relates to a medicinal use of chlorogenic acid, in particular to the application of chlorogenic acid in the preparation of medicines capable of treating female organ tumors. Background technique [0002] Among various tumors originating from female reproductive organs, cervical cancer is the most common cancer in women, and its incidence ranks first among female cancers. Cervical cancer can occur in women of all ages, but it is most common in women between the ages of 25 and 45. The death rate ranks fourth among female cancers, accounting for 4% of all cancer deaths. In the Chinese patent application with the application number of 200610021591.6, the applicant once introduced a drug with the effect of preventing and treating cervical cancer prepared with chlorogenic acid as the main active drug ingredient. [0003] In addition to cervical cancer, breast cancer is also the main malignant tumor that endangers women's health, ranking secon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/216A61P35/00
Inventor 张洁徐小平张舒包旭贺英菊易大朝姚帅
Owner SICHUAN JIUZHANG BIO TECH CO LTD
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