Skin externally-applied liquid state and solid state kreotoxin (liushengtai) composite nano emulsion and preparation thereof
A hexapeptide and nanoemulsion technology, applied in skin care preparations, cosmetic preparations, pharmaceutical formulations, etc., can solve the problems of slow, uncoordinated, and short-term anti-wrinkle reaction, achieve optimal skin anti-aging, and eliminate skin wrinkles. , the effect of scientific strengthening
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[0152] 1. Main raw materials:
[0153] ①Main preparation raw materials of blank nanoemulsion: isopropyl myristate (IPM), caprylic capric acid polyethylene glycol glyceride (Labrasol), polyglycerol fatty acid ester (Plurol Oleique CC497), pure distilled water, absolute ethanol, etc.; ②Main functional ingredients: botulinum toxin (hexapeptide); ③Auxiliary functional ingredients: vitamin E, egg yolk lecithin, ginsenoside, rhodiola, superoxide dismutase (SOD), reduced glutathione ( GSH), fetal bovine serum, hyaluronic acid, ceramide Part III: Preparation of solid botulinum toxin (hexapeptide) composite nanoemulsion for skin external application; ④ Freeze-drying excipient protective agent: mannitol, glycine.
[0154] 2. Main preparation equipment
[0155] One hundred thousandth electronic balance, one ten thousandth electronic balance, one thousandth pharmaceutical balance, liquid fast mixer, timing and constant temperature magnetic stirrer, quartz tube glass double distilled wate...
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