Method for extracting polysaccharide from angelica and application thereof
A technology of angelica and polysaccharides, applied in the field of medical medicine, can solve the problems of preventing or treating osteoarthritis without using polysaccharides, and achieve the effects of long duration of drug effect, easy implementation, and high yield
Active Publication Date: 2010-11-24
广州南峰生物科技有限公司
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Problems solved by technology
At present, there is no relevant report on the use of Angelica sinensis alone in the treatment of osteoarthritis, and there is no report on the use of polysaccharides extracted from Angelica sinensis to prevent or treat osteoarthritis
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The invention discloses a method for extracting polysaccharide from chiretta and an application. The method comprises breaking dry chiretta via a breaker into powder, arranging into an extraction pot, adding ligarine to reflux and defat, adding distilled water into defatted residues to extract, carrying out alcohol precipitation and centrifugation to obtain deposits, removing protein, carrying out acid hydrolysis and gel chromatography separation, freezing and drying to obtain active chiretta polysaccharide. The invention further discloses an application of the active chiretta polysaccharide in the ostarthritis prevention or treatment drug preparation. The invention has definite effective components, definite curative effect, non toxic side effect and easy process.
Description
A kind of method and application of extracting polysaccharide from angelica technical field The invention relates to the technical field of medical medicine, and more specifically relates to a method for extracting active polysaccharides from Angelica sinensis, and also relates to the use of the active polysaccharides extracted from Angelica sinensis in anti-osteoarthritis drugs. Background technique Articular cartilage tissue is mainly composed of chondrocytes and extracellular matrix (ECM), and the main components of ECM are type II collagen, proteoglycan aggregates and water. The degradation and repair of normal articular cartilage matrix are in a continuous dynamic equilibrium state, which is maintained by the secretion of cartilage matrix components by chondrocytes. Although the mechanism of progressive destruction and loss of articular cartilage in primary osteoarthritis is unclear, it has been recognized that osteoarthritis is characterized by metabolic disturbance ...
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IPC IPC(8): C08B37/00A61K31/715A61P19/02
Inventor 汪晖陈廖斌商亮谭扬李小军
Owner 广州南峰生物科技有限公司