Compound compound paracetamol and zincgluconate dispersible tablet and method of preparing the same

Abstract

The invention provides a compound paracetamol and zinc gluconate dispersion tablet which can be crumbled and a preparation method thereof. A single separating granulation method is adopted on the traditional Chinese medicine of compound indigowood root extract powder, thereby avoiding the infections on the whole tablet moulding capability and the disintegration rate because the traditional Chinese medicine ingredient absorbs moisture during the preparation process. The problems that the crumbling and the dissolving out of active ingredient of a common tablet are slow to lead to the result that western medicine ingredient in the medical prescription improves influenza symptom to take effect slowly, and the action is too assuasive. Surface active agent can be further added in cementing substance to accelerate the crumbling; the dosage of the cementing substance is reduced at the same time, thereby further increasing the disintegrative characteristic of the tablet. In addition, the tablet is dispersed more evenly after being crumbled in the water by adding with the surface active agent, thus forming uniform suspension solution, and the medicine dosage for a patient is more accurate. Correctives with bitter taste masking effect can also be further added in the medical prescription to give the prepared dispersion tablet a nice taste, so that the medicine taking compliance of the patient is increased.

Description

technical field [0001] The invention relates to medicines, in particular to a compound dispersible tablet whose active ingredients are acetaminophen, zinc gluconate, dioxpromazine hydrochloride and banlangen extract powder and a preparation method thereof. Background technique [0002] Compound Paracetamol Glucose Zinc Tablets (trade name: Kangbid) is a compound anti-cold preparation composed of acetaminophen, zinc gluconate, dioxpromazine hydrochloride, and banlangen extract powder. Among them, paracetamol can inhibit the synthesis of prostaglandins, and has antipyretic and analgesic effects; dioxpromazine hydrochloride has antitussive, expectorant, antiasthmatic, and antihistamine effects, and the antitussive effect is relatively strong, and its strength is about the same as Because it is equivalent, it has a certain effect of eliminating phlegm and preventing and treating histamine-induced asthma; zinc gluconate can participate in the synthesis and activation of various e...

AI Technical Summary

Problems solved by technology

However, due to the excessive consumption of compound zinc glucosinolate ordinary tablets, the patient will take four tablets at a time, three times a day, that is, the patient will take as many as 12 tablets according to the conventional dosage, causing patients, especially the elderly and children, to suffer a lot. It is difficult to take the medicine according to the doctor's advice, which affects its curative effect and greatly limits the wide application of the medicine. In addition, ordinary tablets have the problem of too slow onset and too mild effect due to the slow disintegration and dissolution. Disintegration and dissolution limit the effect of western medicine ingredients in the prescription to improve cold symptoms