Complex spectral domain optical coherence tomography method and system

Abstract

The invention provides a tomographic method and a system for coherent optics in complex spectrum frequency domain, comprising a broadband light source, a light source coupling mechanism, a combined interferometer, a fiber-optics imaging probe, a spectrograph, a temperature controller and a computer; the method comprises the following steps of: firstly, measuring three groups of interference spectrum in state of three different phases of reference light; secondly, calculating two groups of differential interference spectrums; thirdly, taking the sum and the remainder of the two groups of differential interference spectrums as a real part and an imaginary part for a complex amplitude so as to reconstruct the interference spectrum of the complex amplitude in a wave number space; finally, making an inverse Fourier transform for the interference spectrum of the complex amplitude and obtaining depth-scanning information of a measured sample along an optical axis, that is chromatogram. Under the condition that a regulating device for the phase of the reference light is not used, the tomographic method and the system eliminate the effect for chromatogram quality caused by a parasitic image and a hetero conjugation image, and can realize the tomography which reflects the real structure of the measured sample with the advantages of simple system structure, wide dynamic scope and deep measurement in full scale.

Description

technical field [0001] The present invention relates to optical coherence tomography (Optical Coherence Tomography, OCT for short), in particular to a complex spectrum frequency domain optical coherence tomography (Complex SpectralDomain OCT) method and system. Background technique [0002] Optical coherence tomography (OCT) is a new type of biomedical imaging technology. With the characteristics of non-invasive, non-invasive, high-resolution and high-sensitivity, it can perform high-resolution tomographic imaging on the microstructure of living tissues, and its depth resolution can reach micron level, which is tenth of the existing medical imaging technology. times, it is helpful for the early detection and timely diagnosis of human diseased tissues. Early OCT is a time-domain optical coherence tomography technology. In order to obtain the axial depth information of the sample, the reference arm must scan the axial depth. It collects data point by point within the range of...

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Problems solved by technology

Therefore, the system has the defects of many technical links, complex structure and

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