Novel uses of day lily and day lily total flavones

A technology of day lily and total flavonoids, which is applied in the field of new uses and preparations of day lily and total flavonoids of day lily, and can solve problems such as unreported applied research

Active Publication Date: 2008-12-24
倪健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are few studies on the extraction of tota

Method used

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  • Novel uses of day lily and day lily total flavones
  • Novel uses of day lily and day lily total flavones
  • Novel uses of day lily and day lily total flavones

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0151] Embodiment 1: Capsules

[0152] Cut 9900g of dried day lily into 2-3 cm long sections, soak in 95% ethanol overnight. Heating and extracting with 95% ethanol for 3 times, timing from boiling, the time is 40min, 30min, 30min respectively, filtering, combining the filtrates, recovering ethanol, and obtaining extract A. The residue was heated and extracted twice with 60% ethanol for 40 minutes each time, filtered, the filtrates were combined, and the ethanol was recovered to obtain the extract B. Dilute the extract A with distilled water, filter, pass through the treated AB-8 macroporous resin column, wash with distilled water until the effluent is transparent, elute with 60% ethanol for 3 times the column volume, recover ethanol, and obtain sample 1. Treat extract B in the same way to get sample 2. Sample 1 is 64.3101g, and Sample 2 is 60.9338g. The cream yield is greater than 1.265%. Take the dried extract, add lactose (or starch, or dextrin) at a ratio of 1:0-5, mix ...

Embodiment 2

[0156] Embodiment 2: Preparation and inspection of total flavonoids in day lily

[0157] Cut 9900g of dried day lily into 2-3 cm long sections, soak in 95% ethanol overnight. Heat extraction with 95% ethanol for 3 times, start timing from boiling, the time is 40min, 30min, 30min respectively, filter, combine filtrates, recover ethanol, and obtain extract A. The residue was heated and extracted twice with 60% ethanol for 40 minutes each time, filtered, the filtrates were combined, and the ethanol was recovered to obtain the extract B. Extraction A was diluted with distilled water, filtered, passed through the treated AB-8 macroporous resin column, washed with distilled water until the effluent was transparent, eluted with 60% ethanol for 3 times the column volume, recovered ethanol, and sample 1 was obtained. Treat extract B in the same way to get sample 2. Sample 1 is 64.3101g, and Sample 2 is 60.9338g. The cream yield is greater than 1.265%, and samples 1 and 2 are mixed t...

Embodiment 3

[0163] Embodiment 3: Granules

[0164] Cut 9900g of dried day lily into 2-3 cm long sections, soak in 95% ethanol overnight. Heat extraction with 95% ethanol for 3 times, start timing from boiling, the time is 40min, 30min, 30min respectively, filter, combine filtrates, recover ethanol, and obtain extract A. The residue was heated and extracted twice with 60% ethanol for 40 minutes each time, filtered, the filtrates were combined, and the ethanol was recovered to obtain the extract B. Extraction A was diluted with distilled water, filtered, passed through the treated AB-8 macroporous resin column, washed with distilled water until the effluent was transparent, eluted with 60% ethanol for 3 times the column volume, recovered ethanol, and sample 1 was obtained. Treat extract B in the same way to get sample 2. Sample 1 is 64.3101g, and Sample 2 is 60.9338g. The paste yield is greater than 1.265%. Samples 1 and 2 are mixed, and dextrin is added to make granules through a conven...

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PUM

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Abstract

The invention discloses an application of daylily and total flavonoids thereof in preparing antidepressant drug, in particular discloses an application of daylily and the total flavonoids thereof in preparing medicines for increasing 5-hydroxytryptamine, noradrenalin, dopamine and 5-dydroxy group indoleacetic acid in cerebral cortex. The application of daylily and the total flavonoids thereof in preparing antagonism reserpine medicine is also disclosed. The applications are testified by pharmacological experiment.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine and its effective parts, in particular to a new application of day lily and total flavonoids of day lily and a preparation method thereof. Background technique [0002] Day lily is also known as "day lily", "daily lily", commonly known as forget care grass. It is a plant of the genus Hemerocallis in the family Liliaceae and has rich nutritional ingredients. Its main chemical components are protein, fat, carbohydrates, as well as various vitamins, alkaloids, glycosides, flavonoids, carotene, volatile oil, tannin, and inorganic minerals calcium and phosphorus. According to the "Dictionary of Traditional Chinese Medicine", daylily contains 0.7% alkaloids, 1.8% glycosides, 0.75% flavonoids, and 0.36% β-carotene. Li Shizhen of the Ming Dynasty said in "Compendium of Materia Medica" that it has the effects of calming the nerves and refreshing the brain, increasing wisdom and widen...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P25/24A61K125/00
Inventor 邹忆怀倪健朱陵群
Owner 倪健
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