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165 results about "Cerebral cortex part" patented technology

The cerebral cortex is a most important part of the brain. In humans, it is by far the largest part of the brain. Though this cannot be seen directly, different parts of the cortex have different functions (see diagram).

Time-frequency space electroencephalogram emotion recognition method based on three-dimensional space position embedding

The invention belongs to the field of electroencephalogram signal processing, and provides a time-frequency space electroencephalogram emotion recognition method based on three-dimensional space position embedding, which comprises the following steps of: firstly, constructing a three-dimensional electrode space position matrix based on an international 10-20 system standard, determining a space adjacency relation between electrodes, and calculating a phase locking value to obtain a functional connection matrix; then, deep feature fusion of an electrode spatial position matrix and a functional connection matrix is realized by adopting a hierarchical cross Transform architecture, the spatial position matrix represents spatial distribution features of a cerebral cortex region, and the functional connection matrix quantifies phase synchronization features of cross-brain region neural oscillation and simulates a brain spatial topological structure; and finally, extracting time, frequency and spatial features of the electroencephalogram signals through combination of a graph attention network and bidirectional long-short-term memory with an attention mechanism for emotion recognition. The method can effectively extract space structure information highly related to the emotional state, and significantly improves the accuracy of emotion recognition.
Owner:XIAN UNIV OF POSTS & TELECOMM

Craniocerebral deep electrical stimulation closed-loop regulation and control system and method based on fNIRS dynamic guidance

The invention provides a transcranial deep electrical stimulation closed-loop regulation and control system and method based on fNIRS dynamic guidance. The method comprises the steps that a transcranial alternating current electrical stimulation module applies an electrical signal to a target deep brain region according to preset parameters to carry out electrical stimulation regulation and control; the synchronous triggering module is used for realizing millisecond-level synchronization of a stimulation task and near-infrared brain function data acquisition; the brain function monitoring module analyzes the concentration change of cortex oxyhemoglobin in real time through the multi-channel head cap; the electrical stimulation-response coupling mapping module positions a significant activation channel by adopting statistical test, and establishes an oxyhemoglobin concentration variable and electrical stimulation current amplitude quantitative model; and the dynamic parameter adjusting module optimizes the output current in real time. Personalized closed-loop regulation and control of non-invasive deep brain stimulation can be achieved, cerebral cortex blood oxygen signals are monitored in real time through near-infrared brain function imaging, stimulation parameters are dynamically adjusted, and the accuracy and individualization level of deep brain stimulation are remarkably improved.
Owner:NAT REHABILITATION ASSISTIVE DEVICES RES CENT

Brain region correlation analysis system and method for autistic children

The invention discloses a brain region correlation analysis system and method for autistic children. The system comprises a brain region division module used for dividing the cerebral cortex into a plurality of brain regions; the training data set construction module is used for constructing a training data set, and each training sample comprises a sensor space function connection matrix and a source space function connection matrix corresponding to the sensor space function connection matrix; the signal preprocessing module is used for acquiring a real electroencephalogram signal and calculating a real value of a corresponding sensor space function connection matrix; the deep learning mapping module is used for learning a mapping relation from the sensor space function connection matrix to the source space function connection matrix and outputting a predicted value of the source space function connection matrix; and the brain region correlation analysis module is used for calculating the correlation between the brain regions. The method can be used for accurately analyzing the correlation between the brain areas of the autism children.
Owner:HUAZHONG NORMAL UNIV

Cognitive disorder screening method and device based on VR eye tracker and near-infrared brain imaging

The invention discloses a cognitive impairment screening method and device based on a VR eye tracker and near-infrared brain imaging. The device comprises a virtual reality scene generation module, an eye tracker data acquisition module, a near-infrared brain imaging module, a data evaluation processing module and a cognitive impairment screening module. The eye tracker data acquisition module is used for acquiring an eye movement data information set of a user in a virtual reality scene in real time; the eye movement data information set comprises a fixation point information sequence, a pupil area information sequence and an eye hopping frequency information sequence; the near-infrared brain imaging module is used for acquiring a blood oxygen information set of cerebral cortex when a user completes a cognitive task; the blood oxygen information set of the cerebral cortex comprises a brain blood oxygen information sequence; the data evaluation processing module is used for carrying out evaluation processing on the collected eye movement data information set and the blood oxygen information set of cerebral cortex to obtain cognitive disorder information of the user; the cognitive impairment information comprises information about whether cognitive impairment exists or not and the degree of the cognitive impairment.
Owner:XINJIANG ZHIXIANG ALLIANCE ELECTRONIC TECHNOLOGY CO LTD

Cerebral cortex secreted substance detection method

The invention belongs to the technical field of brain analysis and detection, and particularly discloses a cerebral cortex secreted substance detection method which comprises the following steps: creating a first folder, and storing brain detection data of a detector into the first folder; configuring detection software; creating a second folder, and constructing a first association relationship between the second folder and the first folder; processing the brain detection data through detection software to generate analysis data, and storing the analysis data in a second folder; creating a third folder, and copying the analysis data into the third folder; constructing a second association relationship among the analysis data in the third folder, and marking the analysis data in the third folder through the second association relationship and the first association relationship; outputting the third folder as a detection result; the method has the following advantages that through hierarchical folder management, data backup and parallel processing, data management transparency and processing efficiency are improved, automatic analysis is achieved, data integrity is ensured, and result output is simplified.
Owner:BEIJING HUILONGGUAN HOSPITAL

Hand rehabilitation training glove and system based on electromyographic signal guidance and pressure feedback

The invention provides a hand rehabilitation training glove and system based on electromyographic signal guidance and pressure feedback, and the glove comprises a flexible glove main body which is made of an elastic material, is designed to fit the anatomical structure of a human hand, and is used for collecting bioelectrical signals generated by the remaining hand and forearm muscles of a patient when the patient actively intends to generate power; the embedded signal processing module is used for carrying out amplification, filtering, noise reduction and analog-to-digital conversion processing on the collected original electromyographic signals; and the main control unit is used for calculating time domain and frequency domain characteristic values of the electromyographic signals and identifying the motion intention of the patient based on a preset threshold value or an adaptive algorithm. Weak electromyographic signals are collected and processed in a high-precision mode and immediately converted into local touch pressure feedback corresponding to the functions of the weak electromyographic signals, neural pathway connection between the cerebral cortex and target muscles is enhanced, training interestingness and immersion and compliance of a patient are remarkably improved, and the training effect is improved. And key power is provided for continuous long-term rehabilitation training.
Owner:南昌大学第一附属医院

Adaptive cerebral cortex reconstruction system, method and device based on deep learning and medium

The invention provides a self-adaptive cerebral cortex reconstruction system, method and device based on deep learning and a medium, and the reconstruction system comprises an image preprocessing module which is used for preprocessing input MRI image data to obtain a real curvature image, a real brain tissue segmentation image and a real cerebral cortex; the three-stage grid deformation module is connected with the image preprocessing module; the three-stage grid deformation module comprises three continuous grid deformation modules, and each stage of grid deformation module comprises a deformation model and a physical deformation module; the deformation model is used for predicting a curvature perception static velocity field and a curvature graph; and the physical deformation module calculates differential mapping for each vertex position from the curvature sensing static velocity field so as to generate and obtain a final cerebral cortex surface, so that the accuracy and the efficiency of cerebral cortex reconstruction can be remarkably improved.
Owner:SHANGHAI TECH UNIV

Implantable neural electrode device separated from cerebral cortex through magnetic control telescopic contact

The invention discloses an implantable neural electrode device separated from the cerebral cortex through magnetic control telescopic contact, and belongs to the technical field of brain signal research. Comprising a flexible substrate, a magnetostrictive deformation substrate, a magnetostrictive deformation film, an elastic component and an electrode, a plurality of rectangular grooves which are arranged in order are formed in one side of the flexible substrate; the two magnetostrictive deformation films are attached to the two sides of the magnetostrictive deformation substrate respectively, and the magnetostrictive deformation film on one side is used for fixing the magnetostrictive deformation substrate in the rectangular groove of the flexible substrate; the electrode is fixed on the magnetic deformation substrate and is used for acquiring an electroencephalogram signal; and the elastic assembly is used for pulling the deformed magnetic deformation substrate to recover to a plane state. The device is fixed under the dura mater and can be bent under the drive of a magnetic field, effective contact between the neural electrode and the cerebral cortex is achieved, and compared with a traditional semi-intrusive neural electrode, the detection quality and stability of electroencephalogram signals are improved.
Owner:DALIAN UNIV OF TECH

Whole-brain sleep regulation and control method and device based on ultrasonic-infrasound coupled sound waves

The invention relates to the field of ultrasonic sleep aiding, and provides an ultrasonic-infrasound coupled sound wave whole-brain sleep regulation and control method and device. The whole-brain sleep regulation and control method based on the ultrasound-infrasound coupling sound waves comprises the steps that electroencephalogram signals of a user are collected through electroencephalogram collection equipment; physiological parameters of the user are obtained through physiological state monitoring equipment; a control device is adopted to control and adjust the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, intensity and other parameters of two columns of ultrasonic waves generated by a sound wave emission device according to the electroencephalogram signals and the physiological parameters; a sound wave emitting device is adopted to generate and emit two columns of ultrasonic waves which are close in frequency and face to face, the two columns of ultrasonic waves are fed into the brain face to face, and the two columns of ultrasonic signals inhibit the cerebral cortex activity when passing through the cerebral cortex; meanwhile, interference occurs in the deep brain target nuclear region, low-frequency infrasound beat frequency waves are formed, electroencephalogram slow wave rhythm resonance is induced, sleep-related neural activities of the deep brain target nuclear region are synchronized, and coordinated regulation and control of the whole brain region are achieved.
Owner:SHANDONG UNIV

Phototherapy intelligent regulation and control device and control method thereof, electronic equipment and storage medium

The embodiment of the invention provides a phototherapy intelligent regulation and control device, a control method thereof, electronic equipment and a storage medium, and belongs to the technical field of medical instruments. The phototherapy intelligent regulation and control device comprises a photon cap, a phototherapy module, a monitoring module and a processing module, the phototherapy module and the monitoring module are fixed on a clamping seat of the photon cap, and the processing module is connected with the phototherapy module and the monitoring module; wherein the phototherapy module is used for emitting first near-infrared light, and non-invasive therapy can be achieved in a non-invasive mode; the monitoring module is used for detecting the blood oxygen level of the cerebral cortex and sending the detected oxyhemoglobin concentration to the processing module for analysis, and can monitor and feed back data in real time, so that the treatment process is transparent; the processing module is used for regulating and controlling the treatment parameters of the first near-infrared light emitted by the phototherapy module according to the change speed of the oxyhemoglobin concentration, the treatment parameters can be automatically regulated and controlled according to the detected data, and the intelligent degree of treatment is improved.
Owner:HAINAN UNIV +1

Control system for optimizing sleep quality in cab and control method thereof

The invention provides a control system for optimizing sleep quality in a driving cabin and a control method thereof, and relates to the technical field of driving cabin environment adjusting systems.The control system comprises a sleep-aiding switch key used for starting a switch signal in a one-key mode; the controller assembly is used for sending a control instruction; the brain wave detection assembly is used for collecting weak electric signals of the cerebral cortex and analyzing different brain wave characteristic signals; the seat posture adjusting assembly is used for storing and adjusting the seat state; the artificial natural breathing assembly is used for detecting and controlling the oxygen concentration; the water molecule atomization assembly is used for controlling the atomization amount of water molecules according to the humidity data; the noise interference elimination assembly is used for blocking noise transmission; and the three-in-one control assembly is used for adjusting music, an air conditioner and light. The technical problems that only indexes in a single cab are changed, the sleep state of a driver cannot be detected, and the environment suitable for sleep cannot be automatically adjusted are solved. The technical effect of intelligently improving the sleep quality of the personnel in the driving cabin is achieved.
Owner:SKY WELL (HUAINAN) NEW ENERGY AUTOMOBILE CO LTD +1

Electrode assembly and device for implantable brain-computer interface

The utility model discloses an electrode assembly of an implantable brain-computer interface. The electrode assembly comprises a flexible electrode and a switching device, the detection part of the flexible electrode is in contact with the biological cerebral cortex, an electric signal of the biological brain is obtained through the detection part, and then the electric signal is transmitted to the switching device through the transmission part of the electrode and the first interface; and then the data is transmitted to the external equipment through the second interface of the switching device. In other words, the flexible electrode and the detection part, the transmission path and the first interface included in the flexible electrode are more suitable for being in contact with the biological cerebral cortex and obtaining the electric signals under the condition that brain tissue is not damaged, and the switching device and the second interface included in the switching device are more suitable for transmitting the electric signals and ensuring the signal quality. Through mutual cooperation of the first interface of the flexible electrode and the second interface of the switching device, it is guaranteed that the biological brain tissue is not damaged, electric signals are obtained under the condition that rejection reaction is avoided, and transmission can be carried out under the conditions of high efficiency and signal quality guaranteeing.
Owner:BEIJING XINZHIDA NEUROLOGICAL TECHNOLOGY CO LTD +1

Cerebral cortex stimulation central nervous regulation system and method based on pulse magnetic coil

The invention discloses a cerebral cortex stimulation central nervous regulation system and method based on a pulse magnetic coil, and the system comprises a pulse magnetic stimulation module, a neural signal collection module, a central control module and a man-machine interaction module, and is additionally provided with a three-dimensional positioning module and a multi-level safety monitoring module. The pulse magnetic stimulation module generates a focused pulse magnetic field, the neural signal acquisition module acquires multi-brain-region electric signals, and the central control module dynamically regulates stimulation parameters after analyzing the signals to form closed-loop regulation; the three-dimensional positioning module ensures accurate positioning of the coil, the safety monitoring module monitors parameters in real time and triggers emergency protection, and the man-machine interaction module realizes convenient operation and data management. According to the method, adjustment is completed through initialization, signal acquisition and analysis, precise stimulation, positioning adjustment and safety monitoring. The scheme is non-invasive, accurate, safe and suitable for nerve research and disease treatment, the regulation effect and use safety are improved, and development of the nerve regulation technology is promoted.
Owner:GUANGZHOU YINGZAI LIFE HEALTH BIOTECHNOLOGY CO LTD

Epilepsy lesion positioning method and system based on magnetoencephalogram and medium

The invention discloses a magnetoencephalogram-based epilepsy lesion positioning method and system and a medium, and relates to the technical field of artificial intelligence, and the method comprises the steps: carrying out the preprocessing of a structure image of a patient, carrying out the registration with the magnetoencephalogram of the patient, carrying out the grid division of a cerebral cortex region based on the preprocessed structure image and a registration result, and obtaining a forward model of the patient; performing preprocessing and spine wave detection on the magnetoencephalogram to obtain a spine wave time point sequence; based on the forward model and the ratchet wave time point sequence, using a magnetic dipole algorithm to calculate a source coordinate and a source direction of a ratchet wave time point, and classifying the ratchet wave time point sequence according to the source coordinate and the source direction to obtain a clustering result; calculating the source coordinate and the source direction of the class center of each class in the clustering result by using a magnetic dipole algorithm; generating a clinical report of the patient; according to the positioning method, the problems of large epilepsy diagnosis difference and error proneness caused by level difference of different doctors are solved, and the epilepsy focus position can be quickly determined.
Owner:ARTIFICIAL INTELLIGENCE RES INST OF HEFEI COMPREHENSIVE NAT SCI CENT (ANHUI ARTIFICIAL INTELLIGENCE LAB)

Integrated flexible corticobrain electrode and preparation method thereof

The invention relates to an integrated flexible corticobrain electrode and a preparation method thereof.The flexible corticobrain electrode is composed of a flexible substrate layer, a wire layer and an insulating layer which are sequentially arranged in a stacked mode, the wire layer comprises an electrode contact array, a bonding pad contact array and a wire set, and the wire set spirally surrounds the electrode contact array; the bonding pad contact array is located on the outer side of the wire group; the electrode contact array and the flexible substrate layer and the insulating layer which correspond to each other up and down jointly form a signal acquisition electrode, the wire group and the flexible substrate layer and the insulating layer which correspond to each other up and down jointly form a connecting wire, and the bonding pad contact array and the flexible substrate layer and the insulating layer which correspond to each other up and down jointly form a bonding pad. The integrated flexible cortical brain electrode has the advantages of being small in size, high in flexibility and large in flux, in the using process, the signal collecting electrode can be better attached to a cerebral cortex collecting site, the problems of brain tissue damage and connection failure cannot occur, and the integrated flexible cortical brain electrode is friendly to experimental surgery operation.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Whole cerebral cortex nerve photoelectric information processing method and device under memory mechanism

The invention provides a whole cerebral cortex nerve photoelectric information processing method and device under a memory mechanism. The method comprises the following steps: collecting whole cerebral cortex calcium imaging signals and hippocampus sharp ripple signals generated by an experimental animal aiming at each group of visual stimulation sequences; under the same time step, phase-locked correlation analysis is carried out on the whole cerebral cortex calcium imaging signal and the hippocampal sharp ripple signal to obtain a neural activity association relationship, and the neural activity association relationship comprises a corresponding relationship between different visual stimuli and different signal combinations. The neural photoelectric information incidence relation between the whole cerebral cortex and the deep brain nuclei under the memory mechanism can be analyzed in the visual cognition prediction process, namely visual prediction is carried out by analyzing the whole cerebral cortex activity and the hippocampus sharp ripple discharge, and a basis is provided for constructing a visual prediction model based on the neural activity incidence relation; the attention mechanism about the neural activity association relationship is added for constructing the visual prediction model, so that the visual prediction accuracy of the visual prediction model can be improved.
Owner:TSINGHUA UNIVERSITY

Use of leonurine or its salt in the preparation of a drug for preventing and treating radiation brain injury

The application discloses a new use of Leonurine or a pharmaceutically acceptable salt thereof in the preparation of a medicament for treating radiation-induced brain injury, specifically, providing a safe and effective therapeutic drug for iron death, neuroinflammation, neuron damage and lipid metabolism disorder accompanying the radiation-induced brain injury, solving the technical problem of lack of specific treatment means in the prior art, and having a wide clinical application prospect. Experiments adopt a C57BL / c mouse 30 Gy whole brain X-ray radiation model, and results show that Leonurine can significantly improve the body weight decrease and survival rate of the model mice, reduce the serum IL-6 and IFN-alpha levels, inhibit the activation of microglial cells in the cerebral cortex and hippocampus, protect and repair damaged neurons, and improve the ultrastructure of mitochondria and synapses; meanwhile, the expression of GPX4 and SLC7A11 proteins in the brain tissue is up-regulated, the GSH content is increased to inhibit iron death, and the levels of GPE, GPS and GPC related to lipid metabolism are restored.
Owner:MACAU UNIV OF SCI & TECH +1

Brain-computer interface system

PendingCN122075003Aeliminate relative motionsolve the lossSensorsDiagnostic recording/measuringCerebral meningesRight superficial temporal artery
The invention relates to a brain-computer interface system which comprises a flexible electrode array, a receiving device, a flexible connecting wire and external equipment, wherein the flexible electrode array is implanted into a meninx middle artery in a minimally invasive manner through a superficial temporal artery puncture and a vascular intervention procedure; the receiving device is embedded under the skin of a head and is provided with a signal transmitter; the external equipment is provided with a signal receiver. A flexible electrode array is implanted in an anterior branch or posterior branch of a main branch of a middle meninx artery through a superficial temporal artery intravascular minimally invasive technology, the number of electrodes and the array are arranged according to needs, and a receiving device buried in the subcutaneous part of the head is electrically connected with the flexible electrode array implanted in the middle meninx artery. Craniotomy is not needed, operative complications are avoided, minimally invasive implantation reaches the surface of the cerebral cortex, operation of a doctor is easier, the operation time is shortened, and the comfort level of a patient is improved.
Owner:HANGZHOU MATRIX MEDICAL TECH CO LTD

Inflow enhancement effect-based cerebral cortex puncturing small blood vessel magnetic resonance imaging method and device

PendingCN120976338AImage enhancementImage analysisBlood Vessel TissueVascular magnetic resonance imaging
The invention discloses a cerebral cortex penetrator small blood vessel magnetic resonance imaging method based on an inflow enhancement effect. The method comprises the following steps: modeling a penetrator small blood vessel to generate a blood vessel TOF (Time of Flight) image; calculating the blood vessel-grey matter contrast ratio of the blood vessel TOF image under different FAs and different TRs, and optimizing the FAs and the TRs according to the blood vessel-tissue contrast ratio; obtaining a structural image of the in-vivo brain tissue, performing cortex reconstruction, and calculating an angle of a surface normal of each cortex vertex relative to the B0 field to obtain a cortex angle graph; adjusting a single-layer blood vessel scanning plane angle according to the cortex angle diagram; and according to the optimized FA and TR and the single-layer blood vessel scanning plane angle determined in the step S4, carrying out magnetic resonance imaging on the cerebral cortex perforation small blood vessel. The invention further discloses a cerebral cortex puncturing small blood vessel magnetic resonance imaging device based on the inflow enhancement effect. According to the method and the device, magnetic resonance imaging of the cerebral cortex perforation small blood vessel can be realized under the non-invasive and contrast-agent-free conditions.
Owner:HANGZHOU SEVENTH PEOPLES HOSPITAL

Animal multi-dimensional state recognition system and method based on full-cortical neural activity

The invention provides an animal multi-dimensional state recognition system and method based on full-cortical neural activity, and the system comprises a stimulation generation module which is used for forming target stimulation under the condition that a stimulation generation instruction is received; the full cortical neuron imaging module is used for collecting full cortical nerve response change data generated by the experimental animal under the condition that the experimental animal receives target stimulation; the electroencephalogram signal acquisition module is used for acquiring an electrophysiological signal generated by an experimental animal under the condition that the experimental animal receives target stimulation; the response behavior detection module is used for collecting a physiological response motion state formed by the experimental animal under the condition that the experimental animal receives the target stimulation; and the synchronous recording and analyzing module is used for synchronously analyzing the whole cerebral cortex nerve response change data, the electrophysiological signal and the physiological response motion state to obtain causal association between the nerve activity and the response behavior of the experimental animal under target stimulation. Multi-dimensional state data corresponding to animal response behaviors are synchronously collected, and a foundation is laid for brain function research and analysis.
Owner:TSINGHUA UNIVERSITY

A method and system for automatic electroencephalogram analysis

The present invention relates to the field of medical data analysis technology, and in particular to an automatic electroencephalogram analysis method and system. An automatic electroencephalogram analysis method comprises: taking original electroencephalogram signal data; sending the electroencephalogram signal data into an electroencephalogram signal noise reduction model for processing to output noise-reduced electroencephalogram signal data. The present invention performs noise reduction processing on the original electroencephalogram signal data through the electroencephalogram signal noise reduction model, which can reduce the influence of various noise sources in the original electroencephalogram signal data, thereby improving the quality of the expression of the electrical activity of the patient's cerebral cortex, and facilitating the subsequent use of the electroencephalogram signal data; and in the electroencephalogram signal noise reduction model, the features similar to the influence of noise patterns in the original electroencephalogram signal data are aggregated by dynamic routing, providing a reference for subsequent noise reduction operations, and can effectively adapt to dynamically changing noise to obtain a better noise reduction effect.
Owner:南昌大学第一附属医院

Flash stimulator

ActiveCN310090100SRadiologySurgery
1. Name of the product in this design: Flash Stimulator. 2. Purpose of this design: To serve as an auxiliary diagnostic device in the field of neurology that induces abnormal electrical discharges in the cerebral cortex through light-sensing input from the visual system. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D rendering 1.
Owner:SHENZHEN YINGCHI TECH CO LTD

Portable frequency-adjustable transcranial magnetic stimulation system and stimulation method thereof

The invention discloses a portable frequency-adjustable transcranial magnetic stimulation system and a stimulation method thereof. The system comprises an application program, a central control system and an intervention module, wherein the application program, the central control system and the intervention module are arranged in portable insomnia therapeutic equipment; the application program and the intervention module are both connected with the central control system. According to the invention, accurate matching with human body natural slow wave rhythm (Delta wave 1-4Hz and Theta wave 4-8Hz) is realized by releasing 1-8Hz Gamma low-frequency magnetic pulse waves capable of inhibiting excessive activity through control, slow wave synchronism is enhanced through frequency-phase resonance of magnetic field-neural oscillation, sleep is improved, and an instantaneous alternating magnetic field is generated to penetrate through skull to act on cerebral cortex, so that sleep quality is improved. Compared with a traditional medicine therapy, an invasive therapy and a non-invasive therapy, the side effect is smaller, the risk is lower, sleep can be further improved by playing soothing music, and the sleep neural circuit can be conveniently regulated and controlled at home to conveniently improve insomnia.
Owner:XIAMEN DNAKE INTELLIGENT TECH CO LTD

Method, device, electronic device and storage medium for generating cerebral cortical morphological network

The present application relates to a method, device, electronic device and storage medium for generating a cerebral cortical morphological network, wherein the method comprises: obtaining a cerebral cortical reconstructed image of a target object; segmenting the cerebral cortical reconstructed image to obtain multiple target areas of the cerebral cortex and a vertex set of each target area; connecting the vertices in the vertex set of each target area to obtain a sub-network corresponding to each target area; determining the state of the target leaf node based on whether the target leaf node is adjacent to other leaf nodes; if the state of the target leaf node is a to-be-connected state, determining a connecting leaf node corresponding to the target leaf node; connecting the leaf nodes in the to-be-connected state in each sub-network to the corresponding connecting leaf nodes to generate a cerebral cortical morphological network of the target object. Through the present application, the problem of low efficiency in generating a cerebral cortical morphological network is solved, and the efficiency of generating a cerebral cortical morphological network is improved.
Owner:ZHEJIANG LAB

Aromatherapy application type automatic red and blue light electro-microneedle instrument

The utility model provides an aromatherapy application type automatic red and blue electro-microneedle instrument, which relates to the technical field of micro-needle instruments and comprises an electro-microneedle instrument body, a telescopic mechanism is arranged at the top of the inner side of the electro-microneedle instrument body, and a chassis is arranged at the bottom of the telescopic mechanism. According to the electric microneedle instrument, under the cooperation of the telescopic mechanism, regeneration and repair of stimulated skin can be facilitated through the focal dot matrix injury effect, then radio-frequency current is transmitted to the microneedles through the control of the electric microneedle instrument body, the skin absorption energy can be improved, pores can be shrunk, and through the arrangement of the red and blue light lamp beads, the skin can be effectively absorbed. Red and blue light irradiation can accelerate bacterial death through released singlet oxygen so as to achieve the effects of sterilization and inflammation diminishing, then a semi-closed liquid storage container is arranged, essential oil is stored in the semi-closed liquid storage container, small molecules in the essential oil permeate into skin, blood and particle molecules in an air fumigation mode so as to stimulate the cerebral cortex, and therefore the effects of sterilization and inflammation diminishing are achieved. The effect of relieving pain is achieved.
Owner:張心瑜

Fixing device for conscious imaging of rodents

The utility model discloses a fixing device for conscious imaging of rodents, which belongs to the technical field of microscopic imaging and comprises a head fixing frame, and the head fixing frame comprises an auxiliary supporting component, a displacement mechanism and a head fixing device. The auxiliary supporting assembly is composed of a plurality of fixing rods and fixing pieces, and a head fixing device is arranged on the auxiliary supporting assembly and located over the rotating disc. One end of the auxiliary supporting assembly is provided with a displacement mechanism, and the upper end of the displacement mechanism is provided with an optical panel. The position of the head fixing device can be precisely adjusted, so that the head fixing device is located at a position suitable for microscope observation; the head of a rodent in a natural activity state can be fixed, and four limbs of the rodent are allowed to freely move under stress, so that huge body movement caused by conditions of stress, movement and the like can be eliminated when the rodent is fixed under the device after being trained; the physiological activities of the head, the face, the cerebral cortex and the like of the animal can be subjected to high-time and spatial-resolution image recording in a waking state and a sleeping state.
Owner:FUDAN UNIVERSITY

Text pulse coding method and system based on spatial frequency characteristics

The invention discloses a digital word pulse coding method (DWSFE) and a digital word pulse coding system fusing space and frequency characteristics, which are used for text information processing of a pulse neural network (SNN). The method comprises the following steps: constructing two vocabulary vector space modeling methods, namely interval semantic division vector coding (SSPE) and continuous semantic division vector coding (CSPE), based on a cerebral cortex semantic partitioning principle in neuroscience; converting the semantic vector into a pulse sequence with frequency characteristics through variable intensity Poisson coding (VIPE); and designing an unsupervised clustering SNN architecture containing a lateral suppression mechanism. According to the method, efficient pulse coding of text information is achieved, 100% classification accuracy is achieved under 400-dimensional word vectors, and compared with a traditional word embedding method, the application performance of SNN is greatly improved. The invention provides a low-power-consumption text processing system suitable for a neuromorphic computing device.
Owner:SOUTHEAST UNIV

Gradient tuning type exciting coil structure and system for biological electromagnetic stimulation

The invention discloses a gradient tuning type excitation coil structure and system for biological electromagnetic stimulation, and relates to the technical field of biological electromagnetic stimulation. The coil structure comprises a plurality of layers of 8-shaped stimulation coils which are horizontally placed above a biological electromagnetic stimulation target area, the inner diameter of each layer of 8-shaped stimulation coil is gradually increased layer by layer from bottom to top, and two coil units in each layer of 8-shaped stimulation coil are bilaterally symmetrical. The multi-layer 8-shaped stimulation coil is used for accessing excitation current through the discharge circuit so as to play a biological electromagnetic stimulation role on a target area, so that the focusing performance of the target area can be remarkably improved on the premise of not losing much induced electric field intensity through gradually increasing the inner diameters of the coils from bottom to top layer by layer, and the focusing performance of the target area is improved. Parts of hidden dangers caused by too large focusing area are eliminated, high electric field intensity is generated at the cerebral cortex, effectiveness of brain stimulation is guaranteed, and practical application and popularization are facilitated.
Owner:CHENGDU UNIVERSITY OF TECHNOLOGY

A magnetically controlled telescoping contact decortical implantable neuroelectrode device

The application discloses a kind of implanted nerve electrode devices of magnetic control telescopic contact and separation cerebral cortex, belong to brain signal research technical field.It includes: flexible substrate, magnetostrictive deformation substrate, magnetostrictive film, elastic component and electrode;The flexible substrate side is provided with several rectangular grooves arranged in order;Two pieces of the magnetostrictive film are pasted to the two sides of the magnetostrictive deformation substrate, and the magnetostrictive film on one side is used to fix the magnetostrictive deformation substrate in the rectangular groove of the flexible substrate;The electrode is fixed on the magnetostrictive deformation substrate, for collecting electroencephalogram;The elastic component is used to pull the deformed magnetostrictive deformation substrate to restore flat state.The device is fixed under dura mater, and can be bent under the drive of magnetic field, realizes the effective contact of nerve electrode and cerebral cortex, compared with traditional semi-invasive nerve electrode, improves the detection quality and stability of electroencephalogram.
Owner:DALIAN UNIV OF TECH

Therapy and prevention of prion protein complex infections in non-human animals

There are disclosed therapies and preventions of prion protein complex infections. The transcription of the amyloid precursor protein gene and PrP gene and the RNA transcript are the rate-limiting steps and are most susceptible for blockage and control of the process of amyloid protein formation and PrPsc formation. Thus, therapies and prevention regimes for prion protein complex infections interrupt this process at the level of DNA transcription to RNA, RNA transport to the mitochondrion for protein synthesis and deposition in the cerebral cortex neurons.
Owner:ATIBA JOSHUA O +1