165 results about "Indoleacetic Acids" patented technology

The invention discloses a saline-alkaline tolerant growth-promoting bacillus velezensis AH216 and application thereof, and belongs to the technical field of microbiology and biologica.Bacillus velezensis AH216 is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC No: M 20241496. The saline-alkaline tolerant growth-promoting bacillus velezensis AH216 has the advantages that the saline-alkaline tolerant growth-promoting bacillus velezensis AH216 can be used for preparing saline-alkaline tolerant growth-promoting bacillus velezensis AH216; the bacillus velezensis AH216 provided by the invention can inhibit the growth of pathogenic bacteria of cotton fusarium wilt, and has the growth promoting functions of dissolving potassium, generating indoleacetic acid, cellulase, protease, siderophore and the like; meanwhile, the bacillus velezensis AH216 can tolerate a highly saline-alkaline environment, can improve agronomic characters such as the plant height, the biomass and the leaf area in the corn seedling stage in common soil and saline-alkaline soil, and can promote the development of a corn root system.

Burkholderia, and a composition, use and usage method thereof. Provided are the Burkholderia, and a composition comprising the strain and / or a metabolite, culture, fermentation broth and / or extract thereof. The Burkholderia or the composition thereof can generate a siderophore, induce plants or seeds thereof to generate systemic resistance to plant pathogens, and reduce the chemotaxis of plant pathogens to plants, so that prevention and treatment of plant diseases and insect pests are achieved. In addition, plant root system development can be promoted, a nitrogen fixation effect is provided, a phosphate solubilization effect is provided, indoleacetic acid is generated, and weeds are removed, thereby promoting plant growth.

The invention discloses a bacillus AH83 capable of resisting saline and alkaline and promoting growth and application thereof, and belongs to the technical field of microbiology and biology, the bacillus AH83 is preserved in the China Center for Type Culture Collection with the preservation number of CCTCC No: M 20241495, and the bacillus AH83 is preserved in the China Center for Type Culture Collection with the preservation number of CCTCC No: M 20241495. The AH83 provided by the invention is a new species of bacillus, can inhibit the growth of pathogenic bacteria of cotton fusarium wilt, and has the growth promoting functions of dissolving potassium, generating indoleacetic acid, cellulase, protease, siderophore and the like; meanwhile, the AH83 can survive in a highly saline-alkaline environment, can promote agronomic characters such as plant height, biomass, leaf area and root development in a corn seedling stage when applied in saline-alkaline soil, can also increase soil nutrients and enzyme activity content, and has a promoting effect on lavender seed germination. The strain is of great significance in improving crop yield and stress resistance and developing novel agricultural microbial agents.

The invention provides a spiropolyspora roseus strain for preventing and treating root knot nematode disease, and the preservation number of the spiropolyspora roseus strain is CGMCC No.41822. The invention also provides a microbial inoculum containing the spiropolyspora pink strain, and the microbial inoculum is prepared by the following steps: inoculating a culture medium with the spiropolyspora pink HLF-14-11, and culturing until spores are produced; spores are eluted to prepare a spore suspension, or a bacterial block is cut to serve as a liquid fermentation inoculant; inoculating the inoculant into a liquid culture medium, and carrying out shake culture; and taking the fermentation liquor to prepare liquid, powder and granules. The spiropolyspora pink strain provided by the invention is separated from root-knot nematode oocysts of diseased tomatoes, can parasitize eggs of root-knot nematodes and inhibit incubation of the eggs, fermentation filtrate of the spiropolyspora pink strain has a relatively strong poisoning effect on second-stage larvae of the root-knot nematodes, and the fatality rate of the second-stage larvae reaches 89.1%. Meanwhile, the strain can produce auxin substances such as indoleacetic acid and the like, and plant growth and root development are promoted.

The invention discloses bacillus subtilis subsp. Natto YJ01 and application of the bacillus subtilis subsp. Natto YJ01. The preservation number of the bacillus subtilis subsp. Natto YJ01 strain is GDMCC No: 64944, and the bacillus subtilis subsp. Natto YJ01 strain can be used for dissolving inorganic phosphorus and synthesizing various active substances such as indoleacetic acid, siderophore, protease, gamma-polyglutamic acid, exopolysaccharide and the like. The YJ01 can promote the germination of lavender seeds and the growth in the germination period, and promote the growth and development of corn and oil sunflower plants. Meanwhile, the YJ01 can tolerate a high saline-alkali environment and can improve the physical structure of saline-alkali soil, and key growth indexes such as biomass, leaf area and root development of the corn and the oil sunflower can be effectively improved by applying the YJ01 to the saline-alkali soil. Therefore, the application of the strain YJ01 not only provides a new method for crop growth promotion and saline-alkali soil improvement, but also has important significance for agricultural sustainable development.

The invention discloses and relates to a strain capable of resisting saline and alkaline and producing IAA (Indoleacetic Acid). The strain is classified and named as bacillus atrophaeus, and the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) NO.29799. The strain is preserved in China General Microbiological Culture Collection Center on January 29, 2024. The bacillus atrophaeus HHQGTS13-1 can grow under the condition that the salt content is higher than 3%, can generate indoleacetic acid, cellulase, amylase, protease and ligninase, can inhibit various plant pathogenic bacteria, such as banana anthracnose, tomato gray mold, cotton verticillium wilt, rice sheath blight disease, wheat head blight, banana fusarium wilt, capsicum white spot and the like, and can be used for preparing the bacillus atrophaeus HHQGTS13-1. Particularly, the compound plays an important role in preventing and treating wheat scab, banana anthracnose and capsicum white spot. The strain can promote plant growth in a saline-alkali environment, and can be used for improving soil quality, developing special microbial fertilizers, microbial agents and biopesticides for saline-alkali soil, relieving crop salt stress damage and increasing crop yield.

The invention belongs to the technical field of microorganisms and biological control, and particularly relates to paenibacillus polymyxa and application thereof in biocontrol and growth promotion. Specifically, a strain of paenibacillus polymyxa GLZ219 is obtained through screening, and experiments prove that the paenibacillus polymyxa GLZ219 has a relatively high bacteriostasis rate on pathogenic bacteria of tomato neck and root rot; meanwhile, the strain has a good antagonistic effect on nine common plant pathogens such as Rhizoctonia solani and the like, and can be widely applied to green prevention and control of various crop diseases. Besides, the paenibacillus polymyxa GLZ219 has nitrogen fixing and potassium dissolving capabilities, can secrete heteroauxin and siderophores, and can effectively promote the growth of tomato plants, the plant height of tomato seedlings treated by fermentation liquor of the paenibacillus polymyxa GLZ219 is remarkably increased, diseases can be prevented and controlled, the growth vigor of crops can be improved, the yield and quality of the crops can be improved, and the paenibacillus polymyxa GLZ219 has a wide application prospect.

The invention relates to the technical field of ecological agriculture, and discloses a phytase fungicide fertilizer as well as a production method and application thereof. 1-10 parts of a phytase high expression strain; 1-8 parts of a phytase solution; 1.7 to 9 parts of an embedding material; 3-8 parts of pH buffer particles; 10-30 parts of a micro-carbon carrier; 0.02 to 0.10 part of an indoleacetic acid microcapsule; and 30-60 parts of humus powder. The invention further provides a production method of the phytase fungicide fertilizer. The method comprises the following steps: S1, performing liquid fermentation on a phytase high-expression strain; s2, mixing the thalli with an enzyme solution; s3, adding pH buffer particles into the embedded particles; s4, drying the granules in a spray drying manner; and S5, mixing the dried product with humus powder, and granulating. By constructing a microbial inoculum system containing a phytase high-expression strain, efficient activation and conversion of organic phosphorus resources are realized, and the release efficiency of the fertilizer to phosphorus resources is improved.

The invention belongs to the technical field of microorganisms, and particularly relates to a Prlisteria megatherium strain and application thereof. The invention provides a strain of Pristeria megaterium A3, and the preservation number of the Pristeria megaterium A3 is CGMCC (China General Microbiological Culture Collection Center) No. 31931. The prelisteria megatherium A3 can generate indoleacetic acid (IAA), and can directly promote the elongation of a plant root system, so that the opportunity that a plant is in contact with nutrient substances in soil is increased, the content of endogenous IAA in a plant body is increased, the expression of a plant defense gene is induced, and the stress resistance such as disease resistance and drought resistance of the plant body is improved. Meanwhile, the prelisteria megatherium A3 disclosed by the invention has phosphorus solubilizing capacity, and can convert phosphorus which is difficult to utilize into available phosphorus, so that the content of available phosphorus in soil is increased. In addition, the prelisteria megatherium A3 also has potassium dissolving capacity, and can improve the utilization rate of the fertilizer and promote the growth and development of plants and the absorption of the fertilizer.

The invention belongs to the technical field of microorganisms, and particularly relates to stenotrophomonas maltophilia yg3 and application thereof. The invention discloses stenotrophomonas maltophilia yg3, and the preservation number of the stenotrophomonas maltophilia yg3 is CGMCC (China General Microbiological Culture Collection Center) No.34131. The stenotrophomonas maltophilia yg3 disclosed by the invention has the capability of efficiently synthesizing indoleacetic acid (IAA), and the IAA yield of 98.10 mg / L can be realized without optimization in an NB culture medium containing 5mM L-tryptophan, which is obviously higher than that of other wild strains. Moreover, the stenotrophomonas maltophilia yg3 has a remarkable growth promoting effect on plants (such as hot peppers), pot experiments show that the stenotrophomonas maltophilia yg3 can remarkably increase the number of effective leaves, the plant height and the biomass of the hot peppers, and the stenotrophomonas maltophilia yg3 can be applied to the field of microorganisms. Particularly, the method has important application value in the fields of microbial plant growth promoters and green synthesis of IAA (indoleacetic acid).

The invention relates to the technical field of biology, in particular to application of brassinolide in increasing the yield of lettuce latex. According to the invention, brassinolide is adopted as an active component and acts on lettuce plants, so that the yield of lettuce latex can be remarkably increased, and meanwhile, the contents of sucrose and isopentenyl pyrophosphate in lettuce are further remarkably increased. Compared with indoleacetic acid, the brassinolide provided by the invention is more suitable for improving the gum production performance of the plant lettuce, and the brassinolide and the indoleacetic acid are high in adaptability, so that a more excellent technical effect is obtained. In the use process, the use method of brassinolide is simple, the use amount is small, the function of remarkably improving the yield of lettuce latex, sucrose and isopentenyl pyrophosphate can be achieved by adopting brassinolide with low concentration, the cost is low, the effect is good, no new toxic or side effect is caused to the environment, and the brassinolide is suitable for application and popularization.

The invention relates to the technical field of microorganisms and particularly discloses paenibacillus mucilaginosus as well as a microbial agent and application thereof. The preservation number of the paenibacillus mucilaginosus N-002 is CGMCC (China General Microbiological Culture Collection Center) No.32752, and the preservation number of the paenibacillus mucilaginosus N-002 is CGMCC No.32752. The paenibacillus mucilaginosus N-002 provided by the invention can produce a urease inhibitor and indoleacetic acid at high yield and has no denitrification effect, the urease inhibitor produced by the paenibacillus mucilaginosus N-002 can reduce the urease activity of soil, significantly reduce the ammonia emission and nitrous oxide emission of the soil, especially after a nitrogen fertilizer is applied, is beneficial to soil nitrogen element maintenance, improves the fertilizer efficiency of the nitrogen fertilizer, and has a good application prospect. Meanwhile, the influence of emission of ammonia and nitrous oxide on the environment is reduced; the strain has no denitrification effect, and can increase the proportion of non-denitrifying bacteria in soil and reduce the denitrification effect of the soil after being applied to the soil, so that the emission of nitrous oxide in the soil is reduced, and environmental protection is facilitated.

The invention belongs to the technical field of agricultural microorganisms, and particularly relates to rice endophytic sphingosine vector SY02 and application thereof. The preservation number of the rice endophytic sphingobium yanoikuyae SY02 provided by the invention is CCTCC (China Center For Type Culture Collection) NO: M2026182, and the sphingobium yanoikuyae SY02 has the functions of producing indoleacetic acid, promoting plant growth and seed germination, promoting adventitious bud proliferation of tissue culture seedlings and relieving browning. The sphingosine vector bacterium and the microbial agent prepared through strain fermentation have the advantages of being green, safe, efficient, long-acting and the like, and have good application prospects in the aspects of promoting plant growth and seedling breeding.

The invention discloses bacillus amyloliquefaciens and application of the bacillus amyloliquefaciens in promoting growth of plants in salinized land. The strain is preserved in Guangdong Microbial Culture Collection Center on June 24, 2025, and the preservation number is GDMCC NO: 67014. The bacillus amyloliquefaciens R1 obtained by screening is a high-yield IAA (Indoleacetic Acid), is a bacterial strain capable of remarkably promoting the growth of plants in the salinized land, and has good development potential and application value for promoting the growth of the plants in the salinized land. The problem that in the prior art, microbial strains with the rhizosphere growth-promoting and saline-alkaline-tolerant functions are lacked is solved.

The invention belongs to the technical field of plant seedling raising, and relates to a method for breaking dormancy of iris ensata thunb seeds and accelerating germination, which comprises the following steps: (1) soaking disinfected iris ensata thunb seeds in hydrogen peroxide with the concentration of 3-7wt% for 15-30min; and (2) at 25-30 DEG C, soaking with a mixed solution of gibberellin 3 and indoleacetic acid, and accelerating germination. Hard seed coats are broken through H2O2 soaking treatment, seed coat obstacles and physiological dormancy of the iris ensata thunb seeds are broken through combination of a GA3 + IAA seed soaking mode and fine sand covering germination acceleration, hormones needed by seed germination are supplemented, germination inhibitors existing in the seeds are inhibited, dormancy of the iris ensata thunb seeds is comprehensively relieved, the germination rate of the iris ensata thunb seeds is remarkably increased, and the germination rate of the iris ensata thunb seeds is increased. The germination rate is increased to 80% or above, the germination time can be further shortened, and technical support is provided for large-scale production and application of iris ensata thunb.

The invention provides recombinant escherichia coli, a construction method of the recombinant escherichia coli and application of the recombinant escherichia coli in production of indoleacetic acid, and belongs to the technical field of synthetic biology and microbial metabolism engineering. The recombinant Escherichia coli is obtained by taking Escherichia coli as a chassis cell, introducing an IAA pathway into the chassis cell and knocking out a tnaA gene and an mtr gene; the recombinant escherichia coli can be fermented by taking glucose or cellulose as a substrate to generate IAA; the yield of the synthesized IAA is improved by further optimizing the fermentation time, the fermentation temperature and the composition of a buffer solution, and the synthesized IAA can effectively promote plant growth and has good practicability.

The invention relates to the technical field of agriculture, and discloses an ecological environment-friendly microbial degradation mulching film which comprises the following components in percentage by mass: 50-65% of polylactic acid; 15% to 25% of lignocellulose; 5%-10% of glycerin; 0.5%-2% of nano titanium dioxide; 0.1% to 0.5% of silver nanoparticles; 0.5%-2% of a tea tree oil extract; 15% to 20% of carboxymethyl cellulose; 13%-15% of a plant growth regulator; 5%-10% of an auxiliary agent; the auxiliary agent comprises one or more of an antioxidant, a plasticizer and a light stabilizer, and the plant growth regulator comprises one or more of a seaweed extract, indoleacetic acid or oleanolic acid. By adding nano titanium dioxide and silver nanoparticles into the mulching film, excellent ultraviolet resistance and antibacterial performance of the mulching film are achieved, and the problem that aging of a traditional mulching film is accelerated due to ultraviolet irradiation is solved.

The invention provides a strain of Ralstonia sp. YNK-FB0054 as well as a microbial agent and application thereof, and belongs to the technical field of biology, the strain is Ralstonia wenshanensis, and the preservation number of the strain is CCTCC NO: M 2025293. The strain provided by the invention has the functions of dissolving zinc, fixing nitrogen, decomposing organic phosphorus, dissolving inorganic phosphorus, producing iron carriers and producing indoleacetic acid. The strain and the fungicide taking the strain as the effective active component can promote the germination of plant seeds and the growth of plants, and have high application value.

The invention relates to the field of biomedicine, and mainly relates to application of indoleacetic acid in preparation of products for preventing or treating hypertension. The invention firstly provides application of indoleacetic acid or pharmaceutically acceptable salts thereof in preparation of products for preventing and / or treating hypertension. The invention also provides a product comprising an effective dose of indoleacetic acid or a pharmaceutically acceptable salt thereof. It is found that indoleacetic acid or pharmaceutically acceptable salts thereof can be effectively used for preventing or treating hypertension, and a new way is opened up for treatment of hypertension.

The invention discloses a method for improving the grafting survival rate of castanopsis hystrix, and belongs to the technical field of seedling breeding. The method comprises the following technical steps: (1) stock selection; (2) stock treatment; (3) scion selection; (4) scion treatment; (5) grafting; and (6) fertilization management after grafting. According to the method, the agent A containing the water-soluble compound fertilizer, the indoleacetic acid and the chlorin iron is used for treating the stocks, the agent B containing the indoleacetic acid, the chlorin iron and the manganese sulfate is used for treating scions, scion growth can be promoted, stress resistance can be improved, the healing speed of grafting unions can be increased, the grafting survival rate can be increased, and the budding speed can be increased; the problems of low grafting survival rate and slow budding in the castanopsis hystrix grafting process are solved, and unified management of nursery stocks in the later period and construction of a castanopsis hystrix clonal seed orchard are facilitated.

The invention discloses a bacillus velezensis strain and application thereof. The invention discloses bacillus velezensis WLH (bacillus velezensis), and the preservation number of the bacillus velezensis WLH is CCTCC (China Center for Type Culture Collection) NO: M 20251238. The bacillus velezensis WLH is screened from rhizosphere of cucumber, the WLH is a biocontrol bacterium, can inhibit growth of pathogenic bacteria of cucumber root rot and fusarium wilt by degrading phenolic acid in soil and promote growth of cucumber plants, and the strain can relieve autotoxicity caused by the phenolic acid, inhibit the cucumber root rot and fusarium wilt and promote growth of cucumber plants. The promotion of crop growth comprises the capability of producing indoleacetic acid (IAA) and the capability of solubilizing phosphate, the promotion of germination of cucumber seeds under the stress of mixed phenolic acid and pathogenic bacteria, and the promotion of growth of cucumber seedlings under the stress of mixed phenolic acid and pathogenic bacteria. Soil continuous cropping obstacles generated in cucumber planting are effectively relieved, and a new basis is provided for microbial control of continuous cropping obstacles.

The invention belongs to the field of development and application of microorganisms, and relates to serratia rubra for preventing and treating potato scab and application of the serratia rubra. In order to overcome the defects in the prior art, the invention provides serratia rubra A14 for preventing and treating potato scab and application of the serratia rubra A14, the serratia rubra A14 provided by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.36010. The serratia rubra A14 can be used for preventing and treating potato scab. The strain has remarkable bacteriostatic activity on streptomyces scabies, and has the capabilities of dissolving phosphorus and producing indoleacetic acid (IAA), protease and siderophore. The strain has good biological safety, and the strain is prepared into a microbial agent for green prevention and control of potato scab and has good application prospects.

The invention provides a Bruegeria bivalve CB24031-XJ12 strain and an application thereof, and belongs to the technical field of microorganisms. The Bruegera conchae CB24031-XJ12 disclosed by the invention is preserved in the Guangdong Microbial Culture Collection Center, the preservation number is GDMCC No: 66493, the preservation date is June 10, 2025, and the preservation address is the 5th floor, No. 59 building, No. 100 Courtyard, Xianlie Middle Road, Guangzhou. According to the present invention, the Brugergera bivaleriei CB24031-XJ12 has the 3-indoleacetic acid (IAA) production capacity, and the co-culture of the Brugergera bivaleriei CB24031-XJ12 and the sea grape can significantly promote the growth and the upright branch germination of the sea grape and improve the oxidation resistance of the sea grape, such that the Brugergera bivaleriei CB24031-XJ12 has important significance in the improvement of the yield and the quality of the sea grape.

The invention discloses a ginger endophytic bacterium CQG8 for promoting plant growth and a preparation method and application thereof, the ginger endophytic bacterium CQG8 is classified and named as Pseudomonas putida, is preserved in Guangdong Microbial Culture Collection Center, the address is 59 building, No.100 courtyard, Xianlie Middle Road, Guangzhou City, the preservation date is May 14, 2025, and the preservation number is GDMCC NO: 66334. The ginger endophytic bacterial strain has the activity of producing indoleacetic acid, dissolving phosphorus, dissolving potassium, fixing nitrogen and producing siderophores, and can be used for promoting the growth of ginger and the germination of corn seeds.

The invention provides a strain of underground neosphingobacterium AR5-1 and application thereof in growth promotion and drought resistance, and the strain is named as Novosphingobacterium subraneum in taxonomy, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) NO.35273. The invention also provides a method for preparing the underground neosphingobacterium AR5-1. The invention further provides an application of the underground neosphingobacterium AR5-1 in growth promotion and drought resistance. The underground neosphingosine bacterium is separated from tobacco rhizosphere drought stress soil, and through molecular identification (the similarity of 16S rRNA is 100%) and functional verification, the underground neosphingosine bacterium has the capacity of producing indoleacetic acid (the concentration of IAA is 0.142 + / -0.005 mg / mL) and fixing nitrogen. A bacterial suspension (OD600 = 0.3) prepared from the bacillus subtilis is applied to plant rhizosphere, so that the growth of crops such as tobacco and the like can be remarkably promoted (the biomass is increased by more than or equal to 20%), the drought resistance is enhanced (the drought rehydration recovery rate is increased by 35%), and the bacillus subtilis has the advantages of environmental friendliness and reduction of chemical fertilizer dependence, and is suitable for sustainable agricultural development.

This invention belongs to the field of microbial technology, specifically relating to a strain of Acetobacter peroxide 672 and its applications. The Acetobacter peroxide 672 strain of this invention can enhance the antagonistic activity of Pichia pastoris against Rhizoctonia solani and also antagonizes Colloidal anthracnose, providing a multi-faceted solution for the biological control of crop diseases. Furthermore, the strain possesses the ability to produce indoleacetic acid, which can significantly promote the growth and development of grain crops such as wheat and corn, promote root expansion, enhance nutrient and water absorption, and thus effectively increase biomass. In addition, the strain can tolerate and degrade chemical pesticide components such as imidacloprid and carbendazim, alleviating soil pesticide residue pollution, and can effectively alleviate the inhibitory effects of low pH stress on crops, enhancing their stress resistance. Therefore, the Acetobacter peroxide 672 strain of this invention has significant application value in the biological control of crop diseases, crop growth promotion, soil pesticide residue remediation, and enhancing crop stress resistance.

This invention discloses a method for preparing recycled planting soil from river dredging soil. First, 0.5-1% wt quicklime and 20-30 g / cubic meter of chloropicrin are mixed into low-moisture dredging soil cake, then covered with a film and left to stand at room temperature for 3-4 days to allow the ash to settle. Next, 1-2% wt wood ash, 1-3‰ wt indoleacetic acid, and 3-6% wt magnesium peroxide are mixed into the sterilized dredging soil. Finally, a soil layer structure is laid, thereby creating a planting environment that promotes plant root growth. This invention's preparation method is simple, resource-efficient, and environmentally friendly. It effectively solves the problems of low plant survival rates and slow growth when dredging soil is directly used for planting, and alleviates many problems associated with storing dredging soil.

The invention discloses a method for increasing the content of genistin and genistein in flemingia philippinensis by using potassium. Culturing the flemingia philippinensis tissue culture seedlings in a propagation culture medium, and subculturing to obtain flemingia philippinensis stem segments with leaves; taking stems of the flemingia philippinensis, and culturing the stems in a rooting culture medium to obtain the flemingia philippinensis with the content of genistin and genistein increased; wherein the propagation culture medium is prepared from MS (Murashige and Skoog), 6-benzyladenine, indoleacetic acid and kinetin; the rooting culture medium comprises KNO3, MS (Murashige and Skoog) and naphthylacetic acid, and the MS does not contain KNO3. According to the method for increasing the content of genistin and genistein in the flemingia philippinensis by using potassium, accumulation of active ingredients of genistin and genistein at the root of the flemingia philippinensis is adjusted by adding exogenous potassium ions, so that the utilization rate of the flemingia philippinensis is increased, and the problem of resource shortage of the flemingia philippinensis is relieved.

The invention discloses an application of indoleacetic acid in preparation of a medicine for preventing or treating neuropathic toxicity caused by chemotherapeutics. Experimental results show that the indoleacetic acid (IAA) can significantly relieve pain sensitivity of mice caused by neuropathic toxicity (OIPN) caused by oxaliplatin (OXA), improve morphological damage of dorsal root ganglion (DRG) of the mice and reduce the inflammation level in colon of the mice; however, these benefits are significantly blocked when antagonists are used for the aromatic hydrocarbon receptor (AhR). This indicates that the therapeutic effect of IAA may depend on the activation of the aromatic hydrocarbon receptor (AhR) pathway. The invention provides a new method for treating neuropathic toxicity caused by chemotherapeutics, and expands the application of indoleacetic acid at the same time.

This invention belongs to the field of microbial technology, and more specifically, relates to a high-yielding and stress-resistant growth-promoting bacterium, *Bacillus pyrogenes* YPR-35, and its applications. This strain possesses high production capacity of indoleacetic acid (IAA) and siderophores, as well as potassium-solubilizing and phosphorus-solubilizing abilities. It can be used in the production of IAA and in plant growth processes, significantly promoting crop growth and shortening cultivation time. This invention also provides a bio-agent containing this strain. Pot experiments and field trials have verified that this bio-agent can promote potato plant growth and significantly increase the yield of marketable potatoes, achieving the effect of high yield and increased income. Furthermore, this bacterium exhibits excellent stress resistance, including tolerance to heavy metal stress, acid and alkali stress, and salt stress, demonstrating wide adaptability. Therefore, this invention provides a new strain resource for the microbial fertilizer industry, showing strong application value in rhizosphere growth promotion.