Unlock instant, AI-driven research and patent intelligence for your innovation.

Silver-containing antimicrobial articles and methods of manufacture

A product, silver salt technology, applied in the field of whitening antibacterial products, manufacturing packaged antibacterial products, can solve the problems of exhaustion, not light stability, leaving stains and so on

Inactive Publication Date: 2009-02-18
3M INNOVATIVE PROPERTIES CO
View PDF7 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, they are often not photostable, can stain the skin they come into contact with, and in the case of silver nitrate, can be depleted quickly in aqueous environments

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Silver-containing antimicrobial articles and methods of manufacture
  • Silver-containing antimicrobial articles and methods of manufacture
  • Silver-containing antimicrobial articles and methods of manufacture

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0095] Cotton substrate with high anion content coated with silver sulfate

[0096] Silver sulfate (Colonial Metals Inc., Elkton, MD) and water were mixed so that there were 0.1333 grams (g or gm) of AgSO per 100 grams of aqueous solution. 4 , to prepare a silver sulfate coating solution. Spunlace 100% cotton mesh (50g / m 2 ; 30.48 cm wide, manufactured by Spuntech Industries, Upper Tiberius, Israel, and coated with a slot die. The pump speed was 316 mL / min. The coated web was dried at 356°F (180°C). The oven length is 15.24 meters (m). The speed of the web is 3.048m / min. The dried web was golden yellow. It is rolled up and placed in a heat sealable foil pouch. 4.7 mg total silver per gram of dressing (Method: EPA 6010B using ICP-AES). By the method described above, the release of silver ions was determined to be 4.2 milligrams (mg) Ag + / g Dressing.

[0097] The dressings were die cut and placed in various packaging materials at a water activity of 0.5, and the pac...

example 2

[0102] Silver Sulfate Coated Low Anion Cotton Substrate

[0103] The dressing of Example 2 was prepared in the same manner as Example 1, except that the spunlace 100% cotton web was manufactured by Unitika, Osaka, Japan under the trade name COTTOASE, 280 millimeters (mm) wide; 50 Grams per square meter (gm / m 2 ). This resulted in a dressing with a total of 5.5 mg of silver per gram of dressing (Method: EPA6010B using ICP-AES), 3.6 mg of Ag per gram of dressing as measured by the method in the test protocol + release of silver ions. The dried dressing was yellow in color.

[0104] The dressings were die cut and placed in various packaging materials at a water activity of 0.5, and the packages were heat sealed. The packaged silver dressings were electron beam irradiated at 30 kGy or gamma irradiated at 38 kGy. Samples were stored at room temperature for 1 to 8 weeks prior to evaluation for color change. Table 5 presents the results of these evaluations.

[0105] table...

example 3

[0109] Silver Sulfate Coated Low Anion Cotton Substrate

[0110] The dressing of Example 3 was prepared in the same manner as Example 2, except that the drying temperature was 175°F (79°C). Dry silver sulfate coated cotton was white. The dressing has a total amount of 5.3mg Ag per gram of dressing (Method: EPA 6010B using ICP-AES), and as measured by the method in the test protocol, the dressing has 3.5mg Ag per gram of dressing +release of silver ions. Dressings were die cut and placed in various packaging materials at a water activity of 0.5, then activated carbon canister (ACC) liners were added, the packages were heat sealed, and packages with dressings without liners were also prepared. The packaged silver dressings were electron beam irradiated at 30 kGy or gamma irradiated at 38 kGy. Samples were stored at room temperature for 1 to 8 weeks prior to evaluation for color change. The table shows the effect of the presence of activated charcoal in the packaging on the...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
peel strengthaaaaaaaaaa
Login to View More

Abstract

A silver composition comprising silver sulfate, methods of making antimicrobial articles, particularly packaged antimicrobial articles, methods of whitening antimicrobial articles, and packaged antimicrobial articles.

Description

Background technique [0001] Although wounds heal more effectively in moist environments, bacterial infection poses an increased risk. The use of antibiotics to treat bacterial infections can lead to bacterial resistance. Silver compounds are known to confer antimicrobial effects on surfaces with minimal risk of bacterial resistance emerging. Silver is delivered to a surface in contact with a moist environment, such as a wound, by sustained release of silver ions from the surface. [0002] Silver compositions, such as silver nitrate and silver sulfadiazine, are effective antimicrobial agents used in a variety of applications. However, they are often not photostable, can stain the skin they come in contact with, and in the case of silver nitrate, can be depleted quickly in aqueous environments. The use of silver salts as antimicrobials has included the use of stabilizers to increase photostability, such as in U.S. Patent No. 2,791,518 (Stokes et al.) (using a first solution o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/18B05D5/00
CPCA61L2300/404A61L15/18A61L15/46A01N59/16A61L2/238A61L2300/104A61L2300/606A61L2/08A61K33/38A61P31/00A01N25/34A01N2300/00A61L2/16A61L2/18
Inventor 斯科特·A·伯顿戴维·R·霍尔姆
Owner 3M INNOVATIVE PROPERTIES CO