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Full-integration ultraviolet micro-fluidic chip analyzer

A technology of microfluidic chips and analyzers, which is applied to the analysis of materials, material analysis through optical means, instruments, etc., can solve the problems of inability to realize multi-channel array detection, analysis throughput limitation, and short separation channel size, etc., to achieve Powerful functions, scalability, and user-friendly effects

Inactive Publication Date: 2009-04-01
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI +1
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  • Description
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Problems solved by technology

At present, commercialized UV microfluidic chip analyzers are rare, mainly the MCE-2010 UV microchip electrophoresis system from Shimadzu Corporation of Japan. Due to the use of full-channel linear imaging detection technology, the chip separation channel size Generally short, which directly affects the separation efficiency and degree of separation, and the manufacturing cost of the matching chip is very high, it cannot realize multi-channel array detection, and the analysis throughput is limited

Method used

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  • Full-integration ultraviolet micro-fluidic chip analyzer
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  • Full-integration ultraviolet micro-fluidic chip analyzer

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Embodiment

[0026] 1. Fully integrated UV microfluidic chip instrument structure

[0027] Such as figure 1 The hardware of the fully integrated ultraviolet microfluidic chip instrument shown includes a plug-in chip electrode plate (1) an ultraviolet detection optical system (2), a CD tray type chip mobile adjustment platform (3), a signal acquisition board (4), a high-voltage power supply and control panel (5);

[0028] The ultraviolet detection optical path system (2) includes a deuterium lamp 1, a slit 2, an optical filter 3, a concave mirror 4, a plane grating 5, a beam splitter 6, a chip channel 7, a sample photodiode 8, a reference photodiode 9, Cylindrical mirror 10, rectangular light hole 11;

[0029] The main power supply, chip platform movement control and detection channel optical alignment buttons are located in front of the casing panel, the ultraviolet detection wavelength setting panel, CD tray type chip movement adjustment platform window are located in front of the casin...

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Abstract

The invention provides a full-integrated ultraviolet micro-flow control chip analyzer which can achieve quick and automatic optical alignment and array multi-passage detection; the ultraviolet micro-control chip analyzer is composed of hardware and a control software module. The invention provides a completely novel automatic optical alignment method which directly utilizes the optical principle and uses the software to automatically control the automatic alignment of the chip detection passage and the optical passage; the analyzer firstly achieves the array multi-passage detection of the ultraviolet micro-flow control chip; the operation of the user is simple; and simultaneously, the analyzer provides powerful function expansibility.

Description

technical field [0001] The invention relates to microfluidic analysis platform technology, and in particular provides a fully integrated ultraviolet microfluidic chip analyzer that realizes fast automatic optical alignment and array multi-channel detection. Background technique [0002] The microfluidic chip laboratory, also known as the chip laboratory (Lab-on-A-Chip) or the microfluidic chip (Microfluidic), refers to the sample preparation, reaction, separation and detection involved in the fields of chemistry and biology. , Cell culture, sorting, lysis and other basic operation units are integrated or basically integrated on a chip of several square centimeters (or even smaller), and a network of microchannels is formed to run through the entire system with controllable fluids to replace conventional chemistry or A technique for various functions in biological laboratories. The basic feature and biggest advantage of microfluidic lab-on-a-chip is the flexible combination ...

Claims

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Application Information

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IPC IPC(8): G01N21/17G01N21/01
Inventor 林炳承马波倪春起王昕秦建华
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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