Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of whole herb extract of Tribulus terrestris rich in furostanol saponin and its preparation method

A technology for furostanol saponins and extracts, which is applied in the field of whole herbal extract of Tribulus terrestris and its preparation, can solve the problems of low furostanol saponin content and the like, and achieve the effect of obvious clinical curative effect.

Active Publication Date: 2011-12-14
陕西步长高新制药有限公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a kind of Tribulus terrestris whole herb extract rich in furostanol saponin and preparation method thereof, to overcome the problem of low content of furostanol saponin in the extract existing in the prior art

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1, a kind of whole herb extract of Tribulus terrestris is prepared by the following method, and said method comprises the following steps successively:

[0024] 1. Take the whole Tribulus terrestris, cut it into short sections (0.5-1cm), add water with a pH value of 5.0 for the first decoction, add 8 times the amount of water, carry out reflux extraction, and filter for 2 hours each time; For water with a pH value of 6.0, add 6 times the amount of water for reflux extraction, 1 hour each time, and filter; add water with a pH value of 8.0 for the third decoction, add 6 times the amount of water, and perform reflux extraction for 1 hour each time , filtered, and the filtrates were combined.

[0025] 2. Concentrate the combined filtrate at 55°C (-0.085Mpa) under reduced pressure to a relative density of 1.05 to 1.15, add ethanol to make the alcohol content 65%, let it stand for 18 hours, filter, and then filter the filtrate at 50°C (-0.085Mpa) ) concentrated un...

Embodiment 2

[0028] Embodiment 2, a kind of whole herb extract of Tribulus terrestris is prepared by the following method, and said method comprises the following steps successively:

[0029] 1. Take the whole Tribulus terrestris, cut it into short sections (0.5-1cm), add water with a pH value of 6.0 for the first decoction, add 10 times the amount of water, carry out reflux extraction, and filter for 1.5 hours each time; For water with a pH value of 6.5, add 8 times the amount of water for reflux extraction, 1.5 hours each time, and filter; add water with a pH value of 8.5 for the third decoction, add 8 times the amount of water, and perform reflux extraction for 0.5 hours each time , filtered, and the filtrates were combined.

[0030] 2. Concentrate the combined filtrate under reduced pressure at 40°C (-0.085Mpa) to a relative density of 1.05 to 1.15, add ethanol to make the alcohol content 75%, let it stand for 12 hours, filter, and then filter the filtrate at 60°C (-0.085Mpa) ) concen...

Embodiment 3

[0033] Embodiment 3, a kind of whole herb extract of Tribulus terrestris rich in furostanol saponins, prepared by the following method, the method comprises the following steps in turn:

[0034] 1. Take the whole Tribulus terrestris, cut it into short sections (0.5-1cm), add water with a pH value of 4.5 for the first decoction, add 7 times the amount of water, and carry out reflux extraction, 3 hours each time, filter; For water with a pH value of 5.5, add 7 times the amount of water for reflux extraction, 0.5 hours each time, and filter; add water with a pH value of 8.0 for the third decoction, add 7 times the amount of water, and perform reflux extraction for 1.5 hours each time , filtered, and the filtrates were combined.

[0035] 2. Concentrate the combined filtrate under reduced pressure at 60°C (-0.085Mpa) to a relative density of 1.05 to 1.15, add ethanol to make the alcohol content 60%, let stand for 24 hours, filter, and then filter the filtrate at 40°C (-0.085Mpa) )...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of raw materials extracted from plants, in particular to a whole herb extract of Tribulus terrestris and a preparation method thereof. The purpose of the present invention is to provide a whole herb extract of Tribulus terrestris rich in furostanol saponins and a preparation method thereof, so as to overcome the problem of low furostanol saponin content in the extract in the prior art. A whole herb extract of Tribulus terrestris rich in furostanol saponins is prepared by the following method, which comprises the following steps in turn: 1. Take the whole herb of Tribulus terrestris, cut it into short sections, first decoct it with water, and carry out reflux extraction, Filtration; add water to the second decoction, perform reflux extraction, and filter; add water to the third decoction, perform reflux extraction, filter, and combine the filtrates; 3. Elute the effluent with water until the effluent is colorless through the treated adsorption resin; product.

Description

Technical field: [0001] The invention relates to the technical field of raw materials extracted from plants, in particular to a whole herb extract of Tribulus terrestris and a preparation method thereof. technical background: [0002] Tribulus terrestris is also known as white tribulus, tribulus terrestris, and hard tribulus terrestris. Pungent in nature and flavor, bitter, slightly warm, slightly poisonous, enters the liver and lung meridians, has the effects of dispersing wind, improving eyesight, lowering qi, promoting blood circulation, tonifying kidney and replenishing essence. The traditional medicinal part of Tribulus terrestris is its fruit, which mainly contains steroidal saponins, flavonoids, polysaccharides and alkaloids. The total saponins extracted from Tribulus terrestris mainly include spirostanol (spirostanol) and furostanol (furostanol). The content of saponin is low, the water solubility is large, and it is not easy to crystallize. It has been proved by p...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61P9/00
Inventor 刘建申
Owner 陕西步长高新制药有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com