Preparation method for increasing content of total saponin, low polarity saponin and argininyl fructosy glucose in red ginseng

A technology of arginine disoside and total saponin, which is applied to the processing of small polar saponins and arginine disoside content, increases the field of total saponins in red ginseng, and can solve the problem that ginsenosides are easily lost, lost, and the yield of AFG decreases. And other issues

Active Publication Date: 2009-09-23
CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

[0004] The traditional red ginseng processing method is generally to wash fresh ginseng and put it directly into a pot or drawer. During the heating process, ginseng is directly exposed to water vapor. Heng, Zhang Lichen, etc. Determination of ginsenoside content in steamed ginseng water concentrate. Ginseng Research. 2003, 15(1): 33); at the same time, it is also easy to make the Maillard reaction between maltose and arginine in the opposite direction that is The direction of AFG decomposition is carried out, resulting in a decrease in AFG yield (Zheng Yinan, Meng Xiangying, etc. Research on the formation mechanism and conditions of the new compound arginine glycosides in red ginseng. Chinese Journal of Medicinal Chemistry. 1997, 7(3): 217- 220)

Method used

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  • Preparation method for increasing content of total saponin, low polarity saponin and argininyl fructosy glucose in red ginseng
  • Preparation method for increasing content of total saponin, low polarity saponin and argininyl fructosy glucose in red ginseng
  • Preparation method for increasing content of total saponin, low polarity saponin and argininyl fructosy glucose in red ginseng

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Processing method

[0021] Select 6-8 fresh ginseng, clean them, seal some of them, put them in the steamer box, and steam them at 100°C for 3 hours. When the steaming time is over, let the ginseng cool in the steamer box to 60°C naturally. Then take them out and put them into an oven to dry at 50° C. for 5 days to obtain red ginseng with increased content of total saponins, small polar saponins and arginine diglucoside.

[0022] A part of the above-mentioned washed fresh ginseng was directly put into the above-mentioned drawer as a control group, steamed and dried according to the same conditions, and the red ginseng processed by the traditional method was obtained.

[0023] (2) Sample solution preparation

[0024] Take 1g powder of the red ginseng obtained by the method provided by the present invention and the red ginseng reference standard obtained by the traditional method, add 20ml of methanol, ultrasonically extract at 40°C for 1h, filter, evaporate the meth...

Embodiment 2

[0029] Select 6-8 fresh ginseng, clean them, seal some of them, put them in the steamer box, and steam them at 110°C for 1.5 hours. When the steaming time is over, let the ginseng cool naturally in the steamer box to 60°C, and then take them out. Finally, put them into an oven and dry them at 50°C for 5 days to obtain red ginseng with increased contents of total saponins, small polar saponins and arginine diglucoside.

[0030] A part of the above-mentioned washed fresh ginseng was directly put into the above-mentioned drawer as a control group, steamed and dried according to the same conditions, and the red ginseng processed by the traditional method was obtained.

[0031] Sample solution preparation and sample detection are the same as in Example 1.

[0032] As a result, the content of total saponins of red ginseng obtained by the method provided by the invention increased by 21.73%, the content of small polar saponins increased by 25.41%, and the content of AFG increased by ...

Embodiment 3

[0034] Select 6-8 fresh ginseng, clean them, seal some of them and put them in the steamer of the ginseng box, and steam them at 110°C for 3 hours. When the steaming time is over, let the ginseng cool naturally in the steamer box to 60°C, and then take it out Then put them into an oven and dry them at 50° C. for about 5 days to obtain red ginseng with increased content of total saponins, small polar saponins and arginine diglucoside.

[0035] A part of the above-mentioned washed fresh ginseng was directly put into the above-mentioned drawer as a control group, steamed and dried according to the same conditions, and the red ginseng processed by the traditional method was obtained.

[0036] Sample solution preparation and sample detection are the same as in Example 1.

[0037] As a result, the content of total saponins of red ginseng obtained by the method provided by the invention increased by 51.22%, the content of small polar saponins increased by 83.48%, and the content of AFG...

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Abstract

The invention provides a preparation method for increasing the content of total saponin, low polarity saponins and argininyl fructosy glucose in red ginseng. Fresh ginseng is cleaned and sealed in a food steamer of a ginseng steaming box to be steamed for 1.5-9h within the temperature range of 100-120 DEG C; after being steamed, the ginseng is naturally cooled in the ginseng steaming box to be 60 DEG C, and then is taken out and put into a baking box to be dried at 50 DEG C for 4-5 days, so that the red ginseng is obtained. High pressure liquid chromatographic detection proves that the content of the total saponin of the red ginseng is improved by 6.00-238.15% compared with the traditional method; the content of the low polarity saponins Rk5, Rg6, Rk1, Rh4, Rg3 and Rs3 can be remarkably increased; when mass spectrum is used for semiquantitative analysis, the content of the argininyl fructosy glucose is higher than that of the generally processed red ginseng by 7.14-311.6%.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a processing method for increasing the content of total saponins, small polar saponins and arginine diglycosides in red ginseng. Background technique [0002] Ginseng is the dried root of Araliaceae plant ginseng (Panax ginseng C.A.Meyer). The fresh ginseng that is washed and dried directly is called "raw sun-dried ginseng", and the one that is steamed and dried is called "red ginseng". Among them, white ginseng is cold in medicinal properties and is suitable for deficiency of Qi and Yin; red ginseng is warm in nature and is suitable for people with deficiency of Qi and Yang. Long-term consumption of red ginseng can improve human immunity, anti-fatigue, anti-radiation, inhibit tumors, and adjust the human endocrine system. [0003] Ginseng contains a variety of chemical components, and ginsenoside is the most important type of active component, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61P37/04A61P35/00A61P39/00A61P39/06A61P31/12A61K125/00
Inventor 刘淑莹杜芹芹邢俊鹏宋凤瑞刘志强
Owner CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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