Chinese medicinal preparation for preventing and curing bronchial asthma and method for preparing same

A technology for bronchial asthma and traditional Chinese medicine preparations, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., and can solve problems such as lack of effective treatment methods for systemic regulation.

Inactive Publication Date: 2009-09-23
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, from the perspective of asthma treatment research, the main focus is on local treatment, so there is still a lack of effective treatment methods for systemic regulation, which is an urgent need to strengthen exploration and research.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0051] Astragalus 15kg, Angelica 15kg, Ligustrum lucidum 10kg, Epimedium 10kg, Gonggong leaf 20kg

[0052] Mix 15kg of Astragalus, 15kg of Angelica, 10kg of Ligustrum lucidum, 10kg of Epimedium, and 20kg of Gonggong leaves, add 560kg of water to soak for 30 minutes, decoct 3 times, 1 hour each time. Combine the three decoctions and concentrate to a relative density of 1.10-1.25 at 80°C; add 100 kg of 95% ethanol to make the alcohol content reach 50%. Let stand overnight, filter out the precipitate, recover ethanol, concentrate to a relative density of 1.20-1.30 (measured at 80°C) extract, dry under reduced pressure, and pulverize into fine powder. Mix 10kg of extract powder with dextrin (15kg) at a ratio of 1:1.5 to make a soft material, sieve to make granules, and dry at 65°C under normal pressure for 4 hours. Packed in bags of 5g per pack.

example 2

[0054] Astragalus 20kg, Angelica 20kg, Ligustrum lucidum 20kg, Epimedium 20kg, Gonggong leaf 10kg

[0055] Mix 20kg of Astragalus, 20kg of Angelica, 20kg of Ligustrum lucidum, 20kg of Epimedium, and 10kg of Gonggong leaves, add 720kg of water to soak for 30 minutes, decoct twice, 1.5 hours each time. Combine the two decoctions and concentrate to an extract with a relative density of 1.15-1.20. Add 110kg of ethanol (95%) to make its alcohol content reach 60%. Let it stand overnight, filter off the precipitate, and recover ethanol. Add 170kg of ethanol (95%) again to make its alcohol content be 70%. After 24 hours, the precipitate was filtered off, and the ethanol was recovered and concentrated to an extract with a relative density of 1.30. The extract (10.8kg) and dextrin (21.6kg) were mixed according to the ratio of 1:2 to make a soft material, sieved to make granules, and dried under normal pressure at 70°C for 4 hours. Packed in bags of 10g per bag.

example 3

[0057] Astragalus 30kg, Angelica 10kg, Ligustrum lucidum 15kg, Epimedium 15kg, Gonggong leaf 30kg

[0058] Mix 30kg of Astragalus, 10kg of Angelica, 15kg of Ligustrum lucidum, 15kg of Epimedium, and 30kg of Gonggong leaves, add 12 times the amount of water to soak for 30 minutes, decoct twice, 2 hours each time. Combine the two decoctions and concentrate to an extract with a relative density of 1.15-1.20. Add 220kg of ethanol (95%) to make its alcohol content reach 70%. Stand still for 48 hours, filter off the precipitate, and recover ethanol. Add 140kg of ethanol (95%) again to make its alcohol content be 70%. After 24 hours, the precipitate was filtered off, ethanol was recovered, concentrated under reduced pressure, dried, and pulverized. Mix 10kg of extract powder with dextrin (30kg) in a ratio of 1:3 to make a soft material, pass through a 12-mesh sieve to make granules, granulate (12-mesh sieve, 60-mesh sieve), and dry at 70°C under normal pressure for 4 hours. Packe...

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PUM

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Abstract

The invention relates to a Chinese medicinal preparation for preventing and curing bronchial asthma. The preparation is prepared from radix astragalus, Chinese angelica, glossy privet fruit, epimedium herb, mahonia leaf and other Chinese medicine herbs; animal tests prove that the preparation can reduce the number of acidophil in a bronchoalveolar lavage fluid and blood, improves the pathological changes of inflammation of lung and bronchia and the like. The method uses the strengthening of body resistance and the curing of root causes as principles, starts from the regulation of qi and blood and yin and yang, effectively increases the immunologic function of patients, improves the degree of asthma attack and gradually relieves and even prevents the recurrent attacks of asthma. The Chinese medicinal preparation for preventing and curing bronchial asthma provides an effective Chinese medicinal preparation for preventing and curing asthma for the patients with asthma and has good application prospect.

Description

Technical field: [0001] The invention relates to traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for preventing and treating bronchial asthma and a preparation method thereof. Background technique: [0002] Bronchial asthma (abbreviated as asthma, asthma) is a common chronic disease that threatens public health worldwide, and the prevalence rate varies from 0.13% to 17% in various countries. And its morbidity and mortality are gradually increasing. According to the statistics of the Global Initiative for Asthma (GINA), 160 million people worldwide suffer from this disease, and the incidence of asthma has doubled within 10 to 20 years in many areas. In many countries, the economic burden of asthma treatment is quite heavy both in terms of direct medical consumption and indirect medical consumption, which makes asthma prevention and treatment a priority in the government's health development strategy. The serious harm caused by asth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K9/20A61K9/16A61K9/48A61K9/10A61P11/06
Inventor 郭忻魏莉周吉燕袁颖
Owner SHANGHAI UNIV OF T C M
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