Veterinary compound acanthopanax granules with immunopotentiation and preparation method thereof

An immune-enhancing, Acanthopanax technology, applied in the preparation of the granule, compound Acanthopanax granules for veterinary use, can solve the problem of increased susceptibility to viruses, bacterial diseases, parasitic diseases, decreased immune function of livestock and poultry, and vaccination reactions Enhancement and other issues, to achieve the effect of enhancing the body's immunity, enhancing the body's disease resistance, and enhancing the immune effect

Active Publication Date: 2009-10-21
HENAN XINZHENGHAO BIO ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to prevent and control diseases, the traditional method is to use a large number of drugs. For example, the use of antibiotics as drug additives results in an increasing number of drug-resistant strains, which makes it difficult to control diseases and sharply reduces the immune function of livestock and poultry.
The growth of livestock and poultry is hindered, especially the immune cells such as lymphocytes and macrophages are in a depressed or suppressed state for a long time, which increases the susceptibility to viruses, bacterial diseases, mycoplasma, and parasitic diseases, and can make low pathogenicity pathogens Causes the occurrence of multiple disease syndromes, even to the extent that it is difficult to control, and also leads to enhanced vaccination response, increased side effects or failure of immunization

Method used

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  • Veterinary compound acanthopanax granules with immunopotentiation and preparation method thereof
  • Veterinary compound acanthopanax granules with immunopotentiation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1: Chinese medicine raw materials used: 70kg Acanthopanax and 30kg Astragalus, and 100kg of finished granules were prepared.

[0067] The preparation method comprises the following steps:

[0068] (1) Weigh 70kg of Acanthopanax and 30kg of Radix Astragali, remove impurities, mix them and place them in a multi-functional extraction and concentration unit for two extractions, the first time use 10 times the amount of water of the two medicinal materials for dynamic extraction at 70°C under vacuum Concentrate, decoct for 4 hours, collect the concentrate; secondly, use 8 times the amount of water of the two medicinal materials to conduct low-temperature vacuum dynamic extraction and concentration at 70°C, decoct for 3 hours, mix the two concentrates, and concentrate the mixed liquid to 70°C The clear ointment with a relative density of 1.15 by thermal measurement, the clear ointment is subjected to alcohol precipitation, filtered until clarified, and the ethanol is ...

Embodiment 2

[0070] Example 2: Chinese medicine raw materials used: 60kg Acanthopanax and 40kg Astragalus, and 100kg of finished granules were prepared.

[0071] The preparation method comprises the following steps:

[0072] (1) Weigh 60kg of Acanthopanax and 40kg of Radix Astragali, remove impurities, mix them and place them in a multi-functional extraction and concentration unit for two extractions, the first time use 7 times the amount of water of the two medicinal materials for dynamic extraction at 70°C under vacuum Concentrate, decoct for 2 hours, collect the concentrated liquid; for the second time, use 5 times the amount of water of the two medicinal materials to conduct low-temperature vacuum dynamic extraction and concentration at 70°C, decoct for 1.5 hours, mix the two concentrated liquids, and concentrate the mixed liquid to 70°C The clear ointment with a relative density of 1.20 by heat measurement, the clear ointment is subjected to alcohol precipitation, filtered until clari...

Embodiment 3

[0074] Example 3: Chinese medicine raw materials used: 65kg Acanthopanax and 35kg Astragalus, and 100kg of finished granules were prepared.

[0075] The preparation method comprises the following steps:

[0076] (1) Weigh 65kg of Acanthopanax and 35kg of Radix Astragali, remove impurities, mix them and place them in a multi-functional extraction and concentration unit for two extractions, the first time with 8 times the amount of water of the two medicinal materials for dynamic extraction at 70°C in vacuum Concentrate, decoct for 3 hours, collect the concentrate; secondly, use 6 times the amount of water of the two medicinal materials to conduct low-temperature vacuum dynamic extraction and concentration at 70°C, decoct for 2 hours, mix the two concentrates, and concentrate the mixed liquid to 70°C The clear ointment with a thermal measurement relative density of 1.18, the clear ointment is alcohol-precipitated, filtered until clarified, and the ethanol is recovered from the f...

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Abstract

The invention provides veterinary compound acanthopanax granules with immunopotentiation, which is prepared from the following Chinese medicament raw materials by weight percentage: 70 to 60 percent of acanthopanax and the balance of astragalus root, wherein 100 grams of granules contain 100 grams of crud drugs. The compound acanthopanax granules produced by the method have good stability and safety, are mainly applied to strengthening the immunological effect of a vaccine and strengthening the immunity of organisms and the anti-stress efficacy clinically, and is applied to treating various immunosuppressive diseases of chickens and other animals and birds, strengthening the immunological effect, and treating symptoms of hypoimmunity, inappetence and the like caused by transportations, groups changes, abrupt climate changes and the like.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and relates to a veterinary compound Acanthopanax granule with immune enhancing effect, and also relates to a preparation method of the granule. Background technique [0002] The rapid development of the breeding industry is largely due to the progress of science and technology, but it also brings hidden dangers. The advancement of science and technology has led to the intensive and industrialized development of the breeding industry. The susceptibility of livestock and poultry to pathogenic microorganisms has increased, and diseases have occurred frequently, causing great economic losses. In order to prevent and treat diseases, the traditional method is to use a large number of drugs. For example, the use of antibiotics as drug additives results in an increasing number of drug-resistant strains, which makes it difficult to control diseases and sharply reduces the immune function of l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K9/16A61P37/04
Inventor 王祝义焦黎赵晓峰
Owner HENAN XINZHENGHAO BIO ENG
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