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Enzyme composition and use thereof

An enzyme composition, biological technology, applied in the direction of drug combination, enzyme, application, etc., can solve the problems of worsening symptoms, accompanied by diarrhea, feeling of fullness, etc.

Inactive Publication Date: 2009-12-02
AMANO ENZYME INC +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, in the case of taking the necessary amount at one time, it is accompanied by diarrhea and a feeling of fullness, and it is considered that there is a risk of worsening the symptoms of IBD

Method used

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  • Enzyme composition and use thereof
  • Enzyme composition and use thereof
  • Enzyme composition and use thereof

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Embodiment Construction

[0033] The first aspect of the present invention relates to an enzyme composition for treating or preventing inflammatory bowel disease (IBD). The enzyme composition of the present invention is characterized by containing an enzyme capable of producing oligosaccharides in vivo (hereinafter also referred to as "oligosaccharide producing enzyme"). Enzymes that act in vivo to generate oligosaccharides are used using ingested food components as substrates. The type of enzyme to be used is not particularly limited as long as it has such properties. Also, the source of the enzyme is not limited, and enzymes derived from bacteria, fungi, yeast, actinomycetes, basidiomycetes, plants, or animals can be used. However, the enzyme composition of the present invention exerts its effect in the living body, so an enzyme that acts in the environment of the living body is used. It is particularly preferable to use an enzyme that is stable and works well even in the stomach (that is, an enzym...

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Abstract

Disclosed is a means effective for the treatment or prevention of inflammatory bowel disease. Specifically disclosed is an enzyme composition for the treatment or prevention of inflammatory bowel disease, which utilizes an enzyme capable of producing an oligosaccharide in vivo.

Description

technical field [0001] The present invention relates to enzyme compositions and uses thereof. Specifically, it relates to an enzyme composition used in the treatment or prevention of inflammatory bowel disease, a treatment method using the composition, and the like. Background technique [0002] Inflammatory bowel disease (IBD: Inflamatory Bowel Disease) refers to an inflammatory disease of the digestive tract (mainly the small intestine and large intestine) of unknown cause, specifically ulcerative colitis (UC: Ulcerative Colitis) and Crohn's disease (CD: Crohn's Disease). UC is limited to the large intestine and is a disease in which superficial ulceration and inflammation occur in the mucosa, and there is a continuous lesion from the rectum to the oral side. Symptoms include diarrhea, bloody stools with mucus, abdominal pain, and fever. On the other hand, CD is characterized by noncaseating granulomas with deep longitudinal ulcers and full-thickness inflammation with a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/45A23L1/305A61P1/00A61P29/00C12N9/98
CPCA23V2002/00C12N9/1055C12N9/1048A23L1/30A23L1/034A61K38/45C12N9/00A23L29/06A23L33/10A61P1/00A61P1/04A61P29/00A23V2200/32A23V2250/28
Inventor 城卓志佐佐木诚人小池田聪
Owner AMANO ENZYME INC