Application of penehyclidine hydrochloride oral cavity partial drug administration as dental surgery medicine
A technology of penehyclidine hydrochloride and topical administration, which is applied in the application field of dental surgery drugs, and can solve problems such as patient distress and inconvenient treatment
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0007] Embodiment 1 Pharmacodynamics test
[0008] 1. Test material
[0009] 1.1 Test drug: Penehyclidine hydrochloride, prepared into 8 μg / ml, 16 μg / ml, 32 μg / ml colorless transparent liquid with sterile water for injection, batch number: 090601, provided by Chengdu Lisite Pharmaceutical Co., Ltd.
[0010] 1.2 Positive control drug: penehyclidine hydrochloride injection, specification: 1ml: 1mg, batch number: 081101, prepared into a 16 μg / ml solution with sterile water for injection, provided by Chengdu Lisite Pharmaceutical Co., Ltd.
[0011] 1.3 Main reagents: phenol red, sodium bicarbonate, and normal saline are commercially available.
[0012] 1.4 Experimental animals Class ICR mice, weighing 18-22 g, half male and half male, were provided by Jiancheng Bill Animal Farm in Jianyang City.
[0013] 1.5 Main instruments Electronic balance, BASIC semi-automatic biochemical analyzer.
[0014] 1.6 Experimental environment The room temperature is 18-24°C and the humidity is 40...
Embodiment 2
[0028] Embodiment 2 Adopt the spray preparation method of oral cavity topical administration mode
[0029] Take an appropriate amount of penehyclidine hydrochloride, add appropriate amount of water to make a solution containing 0.01-10 mg per 1 ml, and put it into a bottle with a spray device.
[0030] A Take 4g of penehyclidine hydrochloride, add 1000ml of water and stir to dissolve, add 1.5g of sodium benzoate, stir and dissolve, then divide into spray bottles, 1ml per bottle.
[0031] B. Add 2 g of penehyclidine hydrochloride, add 1000 ml of water and stir to dissolve, add 1.5 g of sodium benzoate, stir and dissolve, then divide into spray bottles, 1 ml per bottle.
Embodiment 3
[0032] Embodiment 3 Adopt the solution preparation method of local oral administration mode
[0033] Take an appropriate amount of penehyclidine hydrochloride, add appropriate amount of water to make a solution containing 0.01-10 mg per 1 ml, put it into a plastic bottle or a glass bottle, and obtain the product.
[0034] A: Take 1 g of penehyclidine hydrochloride, add 1000 ml of water and stir to dissolve, stir and mix well to dissolve, then pack into vials, 1 ml per bottle, sterilize at 121°C for 10 minutes, and then pack.
[0035] B: Take 2 g of penehyclidine hydrochloride, add 1000 ml of water and stir to dissolve, stir and mix well to dissolve, then dispense into vials, 1 ml per bottle, sterilize at 121°C for 10 minutes, and dispense to obtain the product.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com