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Poplar flower effervescent granules for treating avian colibacillosis and preparation method thereof

A technology of poultry colibacillosis and effervescent granules, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and medical formulas. Prepare simple effects

Inactive Publication Date: 2010-03-10
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the dosage forms of Poplar Flos mainly include dosage forms such as tablets and oral liquids, and it has not been found that Poplar Flos is applied to the same technical field of the present invention.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 (by every part of 10g)

[0030] A poplar flower effervescent granule for treating poultry colibacillosis, characterized in that it is made of the following raw materials in parts by weight: 80 g poplar flower extract, extract content ≥ 60%, 20 g berberine sulfate, 400 g anhydrous sugar, water-soluble Starch 280g, methyl starch sodium 20g, citric acid 110g, sodium bicarbonate 90g, isomaltooligosaccharide syrup 250g.

[0031] The preparation steps are as follows:

[0032] (1) Preparation of acid granules:

[0033] Grind citric acid into fine powder, pass through 40 meshes, and dry at 50-60°C for 2-3 hours for later use; weigh 80g poplar flower extract, extract content ≥ 60%, 20g berberine sulfate, anhydrous Mix 400g of sugar, 280g of water-soluble starch, and 20g of methyl starch sodium, and take 1 / 2 of the weight of the mixed raw materials; weigh 110g of citric acid, and mix the above raw materials evenly; add 1 / 2 of 250g (125g ) isomaltooligosaccharide s...

Embodiment 2

[0038] Embodiment 2 (by every part of 10g)

[0039] A poplar flower effervescent granule for treating poultry colibacillosis, characterized in that it is made of the following raw materials in parts by weight: 30 g of poplar flower extract, 20 g of berberine sulfate, 300 g of anhydrous sugar, 200 g of water-soluble starch, and methylated starch Sodium 20g, citric acid 80g, sodium bicarbonate 70g, isomaltooligosaccharide syrup 280g.

[0040] The preparation steps are as follows:

[0041] (1) Preparation of acid granules:

[0042] Grind citric acid into fine powder, pass through 40 mesh, and dry at 50-60°C for 2-3 hours for later use; weigh 30g poplar flower extract, 20g berberine sulfate, 300g anhydrous sugar, and 200g water-soluble starch according to the ratio , sodium starch glycolate 20g and mix evenly, get 1 / 2 of the weight of its mixed raw materials; weigh 80g of citric acid again, mix the above raw materials evenly; add 1 / 2 of 280g isomaltooligosaccharide syrup, press ...

Embodiment 3

[0048] Embodiment 3 (by every part of 10g)

[0049]A poplar flower effervescent granule for treating poultry colibacillosis, characterized in that it is made of the following raw materials in parts by weight: 75g of poplar flower extract, 30g of berberine sulfate, 270g of water-soluble starch, 40g of sodium starch methylate, citron 150g acid, 100g sodium bicarbonate, 300g isomaltooligosaccharide syrup.

[0050] The preparation steps are as follows:

[0051] (1) Preparation of acid granules:

[0052] Grind citric acid into fine powder, pass through 40 meshes, and dry at 50-60°C for 2-3 hours for later use; weigh poplar flower extract 75g, berberine sulfate 30g, water-soluble starch 270g, methylated starch Mix 40g of sodium evenly, and take 1 / 2 of the weight of the mixed raw materials; then weigh 150g of citric acid, and mix the above raw materials evenly; add 1 / 2 of 300g of isomaltooligosaccharide syrup, and make it into soft material, granulated, dried at 60°C for 4 hours, ...

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PUM

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Abstract

The invention relates to poplar flower effervescent granules for treating avian colibacillosis and a preparation method thereof. The poplar flower effervescent granules are made from the following rawmaterials in parts by weight: 3-8 parts of poplar flower extract, 2-3 parts of berberine sulphate, 30-40 parts of anhydrous sugar, 20-30 parts of water-soluble starch, 2-4 parts of sodium carboxymethyl starch, 8-15 parts of citric acid, 7-10 parts of sodium bicarbonate and 25-30 parts of isomaltooligosaccharide syrup. The preparation method comprises the following preparation steps: (1) preparation of acid granules: respectively weighing and evenly mixing the poplar flower extract, the berberine sulphate, the anhydrous sugar, the water-soluble starch and the sodium carboxymethyl starch according to proportion, and then taking one second of the mixture; later weighing and evenly mixing 8-15 parts of citric acid, adding one second of 25-30 parts of isomaltooligosaccharide syrup to make themixture into soft materials and granules routinely, and drying for 3-4 hours at 50-60 DEG C for standby; (2) preparation of basic granules: evenly mixing the balance of main raw materials, then evenlymixing the mixture with 7-10 parts of sodium bicarbonate, and later making granules routinely; and (3) respectively packing the acid granules and the basic granules. The poplar flower effervescent granules for treating avian colibacillosis have the advantages of simple preparation, convenient use and remarkable effect.

Description

technical field [0001] The invention relates to an effervescent granule and a preparation method thereof, in particular to a poplar flower effervescent granule for treating poultry colibacillosis and a preparation method thereof. Background technique [0002] Effervescent technology has entered our country as early as the 1980s, and it is a relatively new pharmaceutical dosage form. At present, effervescent technology is getting more applications in the production of medicines and health care products, and is concerned by many manufacturers and consumers. According to my country's relevant drug laws and regulations, changing the dosage form has become a new drug research direction. At present, the dosage forms of Poplar Flos mainly include dosage forms such as tablets and oral liquids, and it has not been found that Poplar Flos is applied to the same technical field of the present invention. [0003] Therefore, it will be one of the current urgent problems to be solved by ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/46A61K47/36A61P31/04A61K31/4375A61K133/00
Inventor 伦艳霞
Owner TIANJIN SHENGJI GRP CO LTD