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Highly charged microcapsules

A technology of microcapsules and gels, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulations, etc.

Inactive Publication Date: 2010-06-09
AQUEA SCI CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although attempts have been made to combine sunscreens and soaps (i.e., surfactants), none have provided the ideal combination of high sun protection factor (SPF) and long-lasting benefits in an integrity-preserving composition

Method used

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  • Highly charged microcapsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0293] Sunscreen additives for addition to body washes were prepared by adding 1 g Polyquaternium-4 (CELQUAT-200), 1.5 gm MOISTUREGUARD and 12 g UV PEARLS to 13.7 g water. The mixture was stirred until homogeneous to obtain Phase I. Separately, 1 g of PARSOL 1789 was added to 4 g of octocrylene while heating, stirring until homogeneous to obtain phase II. Combine Phase I and Phase II with gentle agitation until homogeneous to obtain Phase III sunscreen additive.

[0294] Add phase III sunscreen additives to 64.5g SUAVE Bodywash and stir until homogeneous. Finally, 2.3 g of titanium dioxide were added with stirring. The final composition is a sunscreen / body wash.

Embodiment 2

[0296] The SPF capability of the sunscreen / body lotion of Example 1 was tested as follows: 50 cm of water was wetted with 10 ml of water delivered via a syringe. 2 the test site. Apply the test sample to the area in accordance with FDA monograph C.F.R. 21. The subject was rubbed for 3 minutes to allow the product to absorb into the skin. After a further two minutes the area was rinsed with 20ml of water and the area was then patted dry per FDA monograph and left for 15 minutes before being irradiated. The skin was exposed to UV radiation and the MED was recorded and compared to the MED of untreated skin. The results are shown in the table below.

[0297] surface

[0298] (how to apply *)

[0299]

[0300] MED: minimum erythematous dose

[0301] I: light source intensity

[0302] This example demonstrates that the sunscreen / body wash improves sun protection by an average SPF of over 18 compared to untreated skin, as measured by this method.

Embodiment 3

[0304] A sunscreen / body lotion is prepared by mixing the following ingredients: 0.1 to 7.5 parts by weight octyl methoxycinnamate, 0.1 to 6 parts by weight octyl salicylate, 0.1 to 5 parts by weight oxybenzone, 1 to 10 parts by weight The cationic surfactant in parts by weight, the quaternary ammonium compound in 0.01 to 1 part by weight and the preservative in 0.01 to 1 parts by weight.

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PUM

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Abstract

The invention encompasses compositions containing sol-gel microcapsules that are highly positively charged. The sol-gel capsules generally contain additives. The invention also encompasses methods for producing highly charged microcapsules using cationic additives which can include cationic polymers. The methods allow for the encapsulation of polar or non-polar active ingredients.

Description

[0001] cross reference [0002] This application claims priority to US Provisional Application No. 60 / 939,318, filed May 21, 2007, which is hereby incorporated by reference in its entirety. Background technique [0003] Exposure to UV light (primarily through the sun's rays) can have many harmful effects, including premature aging of the skin, loss of elasticity, wrinkling, dryness, and an increased risk of skin cancer. There are many sunscreen products on the market today to combat these harmful effects. All of these products contain substances known to filter out some of the sun's harmful rays and are added to creams, ointments, lotions, solutions or suspensions. Such products are usually applied just before anticipated sun exposure to provide short-term protection and are then removed by bathing, washing, or normal desquamation of the skin. Soap in body wash form has been used for many years to remove grease due to its surfactant content and associated charge. Ordinary ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/00A61K8/18A01M29/12A01M29/28
CPCA61K8/11A61K2800/5426A61K8/062A61Q17/04A61Q19/10A61K2800/412D06M23/12
Inventor D·H·特拉伊诺尔H·G·特拉伊诺尔S·M·玛尔科维茨D·L·科姆普顿
Owner AQUEA SCI CORP