N-substituent thiazolone derivative and preparation method and applications thereof

Abstract

The invention relates to an N-substituent thiazolone derivative. The chemical structure of the thiazolone derivative is described as the following formula (I) or formula (II), wherein R1, R2, R3, R4, X and Y groups are detailed in the specification. The N-substituent thiazolone derivative synthetized by the invention has bactericidal activity on sclerotium sclerotiorum, blumeria graminis and the like, has antibacterial activity on staphylococcus aureus, colon bacillus, hay bacillus and the like, and has higher activities than the corresponding thiazolone compound.

Description

technical field The invention relates to an N-substituent thiazolone derivative, in particular to an N-substituent thiazolone derivative with bactericidal effect, and belongs to the technical field of organic chemistry. Background technique Agricultural fungicides refer to chemical agents that can directly kill the spores and mycelium of fungi or bacteria, or inhibit the growth and development of pathogens. The principle of sterilization is to give priority to prevention, supplemented by prevention and control, that is, active prevention and control should be carried out before or at the early stage of harm caused by germs. If the disease has been harmed or caused harm, and then prevent and control, even if the best fungicide is used, the effect will not be satisfactory. Sometimes it even reaches a level that is difficult to control, resulting in reduced or no harvest in agricultural production. The international fungicide market has grown rapidly, with an average annual g...

AI Technical Summary

Problems solved by technology

If the disease has been harmed or caused harm, and then prevent and control, even if the best fungicide is used, the effect will not be satisfactory

Sometimes it even reaches the level of difficult and easy to control, resulting in reduced or no harvest in agricultural production.

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