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Particle analyzer, constant-temperature reaction system and constant-temperature reaction method

A reaction system and constant temperature technology, applied in the field of particle analyzers, can solve the problem that the accuracy of test results needs to be improved, and achieve the effect of prolonging heating or cooling time, reducing influence, and improving accuracy and stability

Active Publication Date: 2010-08-11
SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD +1
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  • Abstract
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Problems solved by technology

Although there is constant temperature control in the reaction pool for fluorescent dyes and blood cells in the prior art, the final test results still need to be improved in terms of accuracy.

Method used

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  • Particle analyzer, constant-temperature reaction system and constant-temperature reaction method
  • Particle analyzer, constant-temperature reaction system and constant-temperature reaction method
  • Particle analyzer, constant-temperature reaction system and constant-temperature reaction method

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Embodiment Construction

[0016] Hereinafter, the present invention will be further described in detail through specific embodiments in conjunction with the drawings.

[0017] In an embodiment, the constant temperature reaction system includes a reaction tank, a dye tube, and a constant temperature control device. The reaction tank provides a constant temperature reaction place for reactants (such as reagents and blood cells), and generally includes a main board and an incubation tank. The incubation tank is located inside the main board. For example, an independent incubation tank is installed in the cavity of the main board or the main board cavity is directly used as an incubation tank. There may be one or more incubation tanks, and the incubation tank may be columnar, spherical or ellipsoidal. The main board is mainly used to provide a constant temperature environment for the reaction of the reactants, and the incubation tank provides a reaction place for the reactants; the dye tube is used to transpor...

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Abstract

The invention discloses a constant-temperature reaction system. The constant-temperature reaction system comprises a reaction tank, a dye pipe and a constant-temperature control device, wherein the reaction tank is used for providing a reaction place for a reactant; the dye pipe is used for delivering a fluorescent dye; one end of the dye pipe is communicated with the reaction tank; and the constant-temperature control device, the reaction tank and the dye pipe are arranged in such a manner that the constant-temperature control device controls the temperatures of the reaction tank and the dyepipe at a set temperature. Constant-temperature control is performed on the fluorescent dye according to the set temperature before the fluorescent dye enters the reaction tank, so heating or coolingtime of the dye is prolonged, the temperature of the dye is closer to the set temperature, the effect of ambient temperature on the dye is reduced, and the correctness and the stability of a measuring result are finally enhanced.

Description

【Technical Field】 [0001] The invention relates to a particle analyzer, in particular to a constant temperature reaction system and method for reagents of the particle analyzer. 【Background technique】 [0002] At present, common particle analyzers (such as cell analyzers) are based on flow cytometry technology to classify and count particles. Take the blood cell analyzer as an example. In this blood cell analyzer, the blood enters the flow chamber through the flow Before cell technology detection, it is necessary to react with reagents under constant temperature conditions. One of the reagents is a fluorescent dye, which is used to stain blood cells. In the detection, the fluorescent signal is detected by an optical detection system to determine the amount of cell nucleic acid. However, this kind of fluorescent dye is relatively sensitive to temperature. Generally, as the temperature decreases, the fluorescence efficiency of the solution of fluorescent substance increases, and the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48G01N21/64
Inventor 闫宝华楚建军郭文恒
Owner SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
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