The invention discloses a novel quick-cooling chemical ice bag and a preparation method of the novel quick-cooling chemical ice bag. The novel quick-cooling chemical ice bag is prepared from the following components in parts by weight: 20 to 30 parts of ammonium chloride, 50 to 60 parts of barium hydroxide, 30 to 40 parts of ammonium nitrate, 2 to 6 parts of polyvinyl alcohol, 10 to 20 parts of ferric chloride and 15 to 20 parts of sodium chloride. The preparation method of the novel quick-cooling chemical ice bag comprises the steps of accurately weighing according to the weight ratio of each component, adding the weighed polyvinyl alcohol into the barium hydroxide and stirring, wherein the stirring speed is 150 to 250 r/min, and the temperature can be heated up to be 70 to 80 DEG C; stopping heating after the solution becomes transparent, enabling the solution to be naturally cooled to room temperature, and obtaining solution A; sequentially adding the ammonium chloride, the ammonium nitrate and the ferric chloride in the solution A under a stirring state, and obtaining solution B by uniformly stirring the mixed solution; adding the sodium chloride in the solution B, and sealing and packaging the obtained solution in a bag when the mixed solution is uniformly stirred and becomes transparent. According to the novel quick-cooling chemical ice bag disclosed by the invention, the refrigerating speed is fast, and the refrigerating temperature is low.