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Application of Chinese yam polysaccharide in preparation of medicament for treating obesity

A technology for yam polysaccharide and obesity, which is applied in the directions of drug combination, drug delivery, and pharmaceutical formulation to achieve the effects of improving immunity, sufficient drug sources, and reducing hyperglycemia.

Inactive Publication Date: 2012-01-04
新疆帕米尔维吾尔药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Has a significant weight loss effect, so far, no relevant reports

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Use the dried rhizome of the original Chinese yam as a raw material, remove plant impurities, weigh 1000g and pulverize it, add 2 times the amount of water to heat, the temperature is 50°C, reflux extraction twice for 2 hours, filter, combine the filtrates, and concentrate to 50% ;

[0022] Add 95% ethanol to the extraction concentrated solution to make the alcohol content of the concentrated solution reach 70%. After the precipitate appears, let it stand for 3 hours, and after the precipitate is fully precipitated, remove the supernatant to collect the precipitate;

[0023] Dry the precipitate to off-white powder to obtain the crude yam polysaccharide, which has a polysaccharide content of 54%, a protein content of 28%, and a starch content of 14%;

[0024] Add the thick yam polysaccharide into distilled water at a ratio of 1:10 by weight, mix well, add protease to act for 1 hour, then add chloroform and isoamyl alcohol at a weight ratio of 5:1, there will be a gel-lik...

Embodiment 2

[0026] Use the dried rhizome of the original Chinese yam as a raw material, remove plant impurities, weigh 1500g and pulverize it, add 5 times the amount of water to heat, the temperature is 100°C, reflux extraction 3 times for 3 hours, filter, combine the filtrates, and concentrate to 50% ;

[0027] Add 95% ethanol to the extraction concentrated solution to make the alcohol content of the concentrated solution reach 70%. After the precipitate appears, let it stand for 6 hours, and after the precipitate is fully precipitated, remove the supernatant to collect the precipitate;

[0028] Dry the precipitate to off-white powder to obtain the crude yam polysaccharide, which has a polysaccharide content of 54%, a protein content of 28%, and a starch content of 14%;

[0029] Add the thick yam polysaccharide into distilled water at a ratio of 1:10 by weight, mix well, add protease to act for 1 hour, then add chloroform and isoamyl alcohol at a weight ratio of 5:1, there will be a gel-...

Embodiment 3

[0031] Use the dried rhizome of the original Chinese yam as a raw material, remove plant impurities, weigh 1300g and pulverize it, add 4 times the amount of water to heat, the temperature is 80°C, reflux extraction twice for 2.5 hours, filter, combine the filtrates, and concentrate to 50% ;

[0032] Add 95% ethanol to the extraction concentrate to make the alcohol content of the concentrate reach 70%, let stand for 5 hours after the precipitate appears, and after the precipitate is fully precipitated, remove the supernatant to collect the precipitate;

[0033] Dry the precipitate to off-white powder to obtain the crude yam polysaccharide, which has a polysaccharide content of 54%, a protein content of 28%, and a starch content of 14%;

[0034] Add the thick yam polysaccharide into distilled water at a ratio of 1:10 by weight, mix well, add protease to act for 1 hour, then add chloroform and isoamyl alcohol at a weight ratio of 5:1, there will be a gel-like precipitate, remove ...

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PUM

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Abstract

The invention relates to an application of Chinese yam polysaccharide in the preparation of a medicament for treating obesity. The Chinese yam polysaccharide is an active ingredient which is extracted and separated from dry rhizomes of Chinese yam, and the extracted and separated Chinese yam polysaccharide and pharmaceutically acceptable carriers or auxiliary ingredients are prepared into a pharmaceutical preparation such as capsules, granules, tablets, pulvis, oral liquid or syrups. A great number of clinical observations and animal experiments show that the Chinese yam polysaccharide has good weight-reducing effect, can be used for curing and improving obesity, effectively reduces the weight of the salad dodger, and is especially applicable to patients with obesity, who also suffer fromhyperglycemia, lower immune response and premature senility.

Description

technical field [0001] The invention relates to a new application of natural active substance yam polysaccharide, in particular to the application of yam polysaccharide in preparing medicine for treating obesity. Background technique [0002] Obesity, the most common metabolic imbalance, is becoming more common around the world, not only in Western societies, but also in developing countries as people become wealthier. In my country, obese patients are increasing year by year, especially in large and medium-sized cities. According to national estimates, obese patients have exceeded 70 million, accounting for 8% of the total population and 17% of the urban population. [0003] Because obesity often induces hypertension, coronary heart disease, hyperlipidemia, fatty liver, cholecystitis, cholelithiasis, diabetes, impaired glucose tolerance, pulmonary insufficiency, obesity can also weaken the body's resistance and make the immune function Decline and abnormal blood rheology c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K9/48A61K9/16A61K9/20A61K9/14A61K9/00A61P3/04A61K36/8945
Inventor 多力坤·马木特
Owner 新疆帕米尔维吾尔药业有限公司